2019
Long‐term GnRH agonist therapy before in vitro fertilization (IVF) for improving fertility outcomes in women with endometriosis
Jaafar S, Sallam H, Arici A, Garcia‐Velasco J, Abou‐Setta A. Long‐term GnRH agonist therapy before in vitro fertilization (IVF) for improving fertility outcomes in women with endometriosis. 2019, 2019 PMCID: PMC6353287, DOI: 10.1002/14651858.cd013240.Peer-Reviewed Original Research
2012
High rate of allergies among women with endometriosis
Matalliotakis I, Cakmak H, Matalliotakis M, Kappou D, Arici A. High rate of allergies among women with endometriosis. Journal Of Obstetrics And Gynaecology 2012, 32: 291-293. PMID: 22369407, DOI: 10.3109/01443615.2011.644358.Peer-Reviewed Original ResearchConceptsAllergic rhinitisFamily historyYale University HospitalPerennial allergic rhinitisAutoimmune inflammatory diseaseStage of endometriosisPrevalence of allergyMain outcome measuresPositive family historyEndometriosis stageAllergic diseasesAutoimmune disordersMedical filesUniversity HospitalInflammatory diseasesPositive historyOutcome measuresEndometriosisAllergyControl groupAsthmaOverall riskWomenRhinitisMedications
2011
Implantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility
Matalliotakis I, Sakkas D, Illuzzi J, Matalliotaki C, Arici A. Implantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility. Journal Of Endometriosis And Pelvic Pain Disorders 2011, 3: 86-92. DOI: 10.5301/je.2011.8528.Peer-Reviewed Original ResearchTubal factor infertilityMale infertilityTubal infertilityInfertility groupEndometriosis groupFactor infertilityImplantation rateAge-matched control groupMale infertility groupTubal infertility groupICSI treatment cyclesReduced pregnancy rateMethods Five hundredDelivery rateNumber of embryosConsecutive IVFIVF treatmentIVF programPregnancy rateUterine receptivityEndometriosisTreatment cyclesControl groupInfertilityPatientsEndometriosis: Pathogenesis and Management of Pain
Kulp J, Arici A. Endometriosis: Pathogenesis and Management of Pain. 2011, 40-49. DOI: 10.1002/9781444391855.ch4.Peer-Reviewed Original ResearchNonsteroidal anti-inflammatory medicationsGonadotropin-releasing hormone agonistAnti-inflammatory medicationsChronic pelvic painDysfunctional immune responseManagement of painOral contraceptive pillsSymptoms of endometriosisTime of laparoscopyEtiology of endometriosisSymptomatic endometriomasPelvic painSurgical treatmentHormone agonistMedical managementRetrograde menstruationContraceptive pillsLikely multifactorialImmune responseCommon conditionEndometriosisGenetic predispositionPainStem cellsPopulation of lesions
2010
Uterine Anomalies in Women with Endometriosis
Matalliotakis I, Goumenou A, Matalliotakis M, Arici A. Uterine Anomalies in Women with Endometriosis. Journal Of Endometriosis And Pelvic Pain Disorders 2010, 2: 213-217. DOI: 10.1177/228402651000200406.Peer-Reviewed Original ResearchUterine anomaliesSeptate uterusFamily historyFirst-degree family historyYale University HospitalStage of endometriosisReproductive technology proceduresUnicornuate uterusDidelphic uterusMenstrual characteristicsSevere endometriosisUterine malformationsPremature birthMean ageMedical filesUrinary tractUniversity HospitalSpontaneous abortionMain symptomsFamiliar aggregationEndometriosisCongenital malformationsControl groupCommon malformationsUterusAssessment of Oocyte and Embryo Quality in Women with Endometriosis
Matalliotakis I, Cakmak H, Sakkas D, Matalliotaki C, Arici A. Assessment of Oocyte and Embryo Quality in Women with Endometriosis. Journal Of Endometriosis And Pelvic Pain Disorders 2010, 2: 87-94. DOI: 10.1177/228402651000200206.Peer-Reviewed Original ResearchTubal factor infertilityOocyte corona cumulus complexIntracytoplasmic sperm injectionFactor infertilityEndometriosis groupHigher total gonadotropin requirementsTubal factor groupTwo-pronuclear oocytesReproductive technology cyclesPresence of endometriosisHigher cancellation rateAssessment of oocytesOvarian reserveGonadotropin requirementsIVF treatmentIVF programDelivery rateEmbryo gradeMature folliclesEndometriosisSperm injectionCancellation ratePatientsDay 2Peak E2Endometriosis-associated Lyme
Matalliotakis I, Cakmak H, Ziogos M, Kalogeraki A, Kappou D, Arici A. Endometriosis-associated Lyme. Journal Of Obstetrics And Gynaecology 2010, 30: 184-186. PMID: 20143981, DOI: 10.3109/01443610903470270.Peer-Reviewed Original ResearchConceptsLyme diseaseIVF-ET procedureChronic fatigue syndromeCases of patientsSystemic lupusRheumatoid arthritisSjögren's syndromeFatigue syndromeMultiple sclerosisSerological findingsMedical filesEndocrine diseasesEndometriosisDiseaseSyndromeBorrelia burgdorferiWomenPatientsArthritisComplicationsSclerosisLupusPregnancyFeverMigraine
2009
Impact of endometriosis on IVF outcomes
Gafni-Kane A, Vitiello D, Arici A. Impact of endometriosis on IVF outcomes. Expert Review Of Obstetrics & Gynecology 2009, 4: 125-132. DOI: 10.1586/17474108.4.2.125.Peer-Reviewed Original ResearchEfficacy of IVFReproductive-age womenSuccess of IVFTreatment of infertilityPoor oocyte qualitySpectrum of diseaseImpact of endometriosisIVF outcomesEndometrial receptivityMinimal diseasePelvic adhesionsEndometrial glandsUterine cavityAffected womenSevere diseaseEndometriosisOocyte qualityDiseaseAdverse effectsWomenIVFAberrant growthPurported meansNatural fecundityInfertilityAssociation of endometriosis with family history of non-Hodgkin's lymphoma: presentation of 10 cases.
Matalliotakis I, Cakmak H, Fragouli Y, Zervoudis S, Neonaki M, Arici A. Association of endometriosis with family history of non-Hodgkin's lymphoma: presentation of 10 cases. JBUON 2009, 14: 699-701. PMID: 20148465.Peer-Reviewed Original ResearchConceptsFirst-degree relativesFamily historyHodgkin's lymphomaMean ageHistory of NHLOnset of endometriosisCases of endometriosisStage of endometriosisAssociation of endometriosisPositive family historyEvidence of associationMain complaintMedical recordsEndometriosisStage IIINHLLymphomaStage IIFamilial riskWomenSubsequent developmentAgeFirst-generation womenRiskAssociation
2008
Regulation and activation of ezrin protein in endometriosis
Ornek T, Fadiel A, Tan O, Naftolin F, Arici A. Regulation and activation of ezrin protein in endometriosis. Human Reproduction 2008, 23: 2104-2112. PMID: 18552365, DOI: 10.1093/humrep/den215.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsEctopic endometrial tissuePathogenesis of endometriosisWestern blot analysisEndometrial tissueNormal endometriumEctopic endometrial stromal cellsNormal endometrial stromal cellsEctopic endometrial tissue samplesEndometrial tissue samplesEzrin proteinMembrane invasionBlot analysisExpression of ezrinEndometriosisStromal cellsEutopicPotential markerTissue samplesWomenInvasive characteristicsCell invasionEctopic sitesEndometriumInvasive potentialMedical treatment options for endometriosis
Mahutte N, Arici A. Medical treatment options for endometriosis. 2008, 95-108. DOI: 10.3109/9780203091425-10.Peer-Reviewed Original ResearchReproductive-age womenMedical treatment optionsPrevious surgical incisionPosterior culDeep dyspareuniaPelvic painChocolate cystsEndometrial tissuePelvic sidewallTreatment optionsAge womenRectovaginal septumSurgical incisionUterosacral ligamentsEndometriosisDependent portionWomenDyspareuniaDysmenorrheaPainInfertilityLungUterusPelvisCysts
2005
Immunology of endometriosis.
Ulukus M, Arici A. Immunology of endometriosis. Minerva Obstetrics And Gynecology 2005, 57: 237-48. PMID: 16166933.Peer-Reviewed Original ResearchConceptsPathogenesis of endometriosisEctopic endometrial cellsEndometrial cellsAutoimmune diseasesImmune cellsNatural killer cell cytotoxicityPresence of autoantibodiesKiller cell cytotoxicityReproductive-age womenRetrograde menstruation theoryRetrograde menstruationCellular immunityHumoral immunityUterine cavityEctopic endometriumEndometriotic diseaseAge womenT cellsPeritoneal cavityEnigmatic disorderEndometriosisCell cytotoxicityImpaired capacityPathogenesisStromal cells
2004
Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: A Potential Mechanism for the Pathogenesis of Endometriosis
Luk J, Seval Y, Kayisli UA, Ulukus M, Ulukus CE, Arici A. Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: A Potential Mechanism for the Pathogenesis of Endometriosis. The Journal Of Clinical Endocrinology & Metabolism 2004, 90: 1805-1811. PMID: 15613411, DOI: 10.1210/jc.2004-1813.Peer-Reviewed Original ResearchConceptsHuman endometrial endothelial cellsIL-8 mRNAEndometrial endothelial cellsIL-8 expressionSex steroidsEndothelial cellsEutopic endometriumCultured human endometrial endothelial cellsIL-8 immunoreactivityEffects of estradiolEutopic endometrial tissuesPathogenesis of endometriosisInterleukin-8 expressionMenstrual cycle phaseEndothelium-specific markersEndometriosis implantsInflammatory basisCytokine levelsEndometriotic implantsInflammatory mediatorsChemokine expressionEndometrial tissueInflammatory aspectsIL-8EndometriosisEndometriosis and Inflammation in Infertility
HALIS G, ARICI A. Endometriosis and Inflammation in Infertility. Annals Of The New York Academy Of Sciences 2004, 1034: 300-315. PMID: 15731321, DOI: 10.1196/annals.1335.032.Peer-Reviewed Original ResearchConceptsPeritoneal fluidEndometriosis-associated inflammationTubal factor infertilityRate of womenReproductive failureProinflammatory mediatorsFactor infertilityInflammatory factorsPregnancy rateEndometriosisAdvanced stageAngiogenic factorsConfounding factorsInflammationGrowth factorInfertilityWomenReproductive technologiesRecent dataRecent reportsReproductive organsElevated amountsAspects of reproductionFactorsFailure
2003
Estrogen regulates MCP-1 in endometrial cells differently in women with endometriosis and may involve a non-genomic pathway
Halis G, Taskiran S, Kayisli U, Arici A. Estrogen regulates MCP-1 in endometrial cells differently in women with endometriosis and may involve a non-genomic pathway. Fertility And Sterility 2003, 80: 33. DOI: 10.1016/s0015-0282(03)01888-0.Peer-Reviewed Original ResearchApoptosis and the Pathogenesis of Endometriosis
Garcia-Velasco J, Arici A. Apoptosis and the Pathogenesis of Endometriosis. Seminars In Reproductive Medicine 2003, 21: 165-172. PMID: 12917786, DOI: 10.1055/s-2003-41323.Peer-Reviewed Original ResearchConceptsPathogenesis of endometriosisEndometrial cellsSex steroid modulationDisease-free womenEutopic endometrial cellsBcl-2/BaxEndometriotic implantsSteroid modulationInflammatory environmentInflammatory reactionAbnormal survivalEndometriosisApoptosis-related genesFas ligandPhysiologic processesEarly eventsPathogenesisApoptosis
2001
Estradiol fails to down-regulate monocyte chemotactic protein-1 (MCP-1) expression in endometrial cells of women with endometriosis.
Arici A, Bahtiyar M, Seli E, Senturk L. Estradiol fails to down-regulate monocyte chemotactic protein-1 (MCP-1) expression in endometrial cells of women with endometriosis. Fertility And Sterility 2001, 76: s47. DOI: 10.1016/s0015-0282(01)02155-0.Peer-Reviewed Original ResearchEndometriosis and assisted reproductive technologies: are outcomes affected?
Mahutte N, Arici A. Endometriosis and assisted reproductive technologies: are outcomes affected? Current Opinion In Obstetrics & Gynecology 2001, 13: 275-279. PMID: 11396650, DOI: 10.1097/00001703-200106000-00005.Peer-Reviewed Original Research
2000
Interleukin-8 Increases Endometrial Stromal Cell Metalloproteinase Activity: Possible Role in Endometriosis
Mulayim N, Savlu A, Arici A. Interleukin-8 Increases Endometrial Stromal Cell Metalloproteinase Activity: Possible Role in Endometriosis. Fertility And Sterility 2000, 74: s22. DOI: 10.1016/s0015-0282(00)00784-6.Peer-Reviewed Original ResearchPossible roleEndometriosisImplantation defect in endometriosis: endometrium or peritoneal fluid.
Selam B, Arici A. Implantation defect in endometriosis: endometrium or peritoneal fluid. Society Of Reproduction And Fertility 2000, 55: 121-8. PMID: 10889841.Peer-Reviewed Original ResearchConceptsEndometrial receptivityPeritoneal environmentRole of alterationsCytokine concentrationsPeritoneal fluidCell adhesion moleculeEndometriosisClinical observationsHormone analogueDirect actionAdhesion moleculesIron metabolismBiochemical factorsImplantation defectsImplantationWomenRecent studiesFluid microenvironmentPossible mechanismReceptivityEndometriumGonadotrophinDerangement