2014
Early Life Stress Inhibits Expression of Ribosomal RNA in the Developing Hippocampus
Wei L, Hao J, Kaffman A. Early Life Stress Inhibits Expression of Ribosomal RNA in the Developing Hippocampus. PLOS ONE 2014, 9: e115283. PMID: 25517398, PMCID: PMC4269428, DOI: 10.1371/journal.pone.0115283.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDNA MethylationDNA, RibosomalFemaleHippocampusMaleMaternal DeprivationMiceMice, Inbred BALB CPromoter Regions, GeneticReal-Time Polymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionRNA, MessengerRNA, RibosomalStress, PsychologicalConceptsEarly life stressSecond weekHippocampal growthAbnormal hippocampal functionNormal hippocampal developmentNormal mouse hippocampusLife stressMaternal separationMouse hippocampusMouse modelHippocampal developmentHippocampal functionHippocampus developmentNovel molecular mechanismDaily separationHippocampusWeeksDNA methylationInhibits expressionAdulthoodExposureMolecular mechanismsRNA contentGradual declineNormal growth
2010
Early life stress increases anxiety-like behavior in Balbc mice despite a compensatory increase in levels of postnatal maternal care
Wei L, David A, Duman RS, Anisman H, Kaffman A. Early life stress increases anxiety-like behavior in Balbc mice despite a compensatory increase in levels of postnatal maternal care. Hormones And Behavior 2010, 57: 396-404. PMID: 20096699, PMCID: PMC2849915, DOI: 10.1016/j.yhbeh.2010.01.007.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAnxietyAnxiety, SeparationCorticosteroneDNAFemaleGroomingHippocampusMaleMaternal BehaviorMaternal DeprivationMiceMice, Inbred BALB CMice, Inbred C57BLMotor ActivityReverse Transcriptase Polymerase Chain ReactionRNAStress, PsychologicalTriiodothyronine