ACVR1/ALK2-p21 signaling axis modulates proliferation of the venous endothelium in the retinal vasculature
Pak B, Kim M, Han O, Lee H, Dubrac A, Choi W, Yang J, Boyé K, Cho H, Citrin K, Kim I, Eichmann A, Bautch V, Jin S. ACVR1/ALK2-p21 signaling axis modulates proliferation of the venous endothelium in the retinal vasculature. Angiogenesis 2024, 27: 765-777. PMID: 38955953, DOI: 10.1007/s10456-024-09936-6.Peer-Reviewed Original ResearchBone morphogenetic proteinVenous endotheliumProliferation of endotheliumBone morphogenetic protein signalingRetinal vesselsActivin A type I receptorExpression of CDKN1A/p21Bone morphogenetic protein receptorProliferation of endothelial cellsCell cycle progressionRetinal vasculatureEndothelial proliferationACVR1/ALK2I receptorEndotheliumEndothelial cellsCycle progressionModulate angiogenesisActive proliferationMorphogenetic proteinsProliferationContext of angiogenesisAngiogenesisVasculatureCDKN1A/p21