The effect of doxapram on brain imaging in patients with panic disorder
Garakani A, Buchsbaum MS, Newmark RE, Goodman C, Aaronson CJ, Martinez JM, Torosjan Y, Chu KW, Gorman JM. The effect of doxapram on brain imaging in patients with panic disorder. European Neuropsychopharmacology 2007, 17: 672-686. PMID: 17560768, PMCID: PMC2695988, DOI: 10.1016/j.euroneuro.2007.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceBrainCentral Nervous System StimulantsDoxapramFemaleHumansMagnetic Resonance ImagingMalePanic DisorderPositron-Emission TomographySeverity of Illness IndexSingle-Blind MethodTime FactorsConceptsPanic disorder patientsDisorder patientsPlacebo saline solutionEffects of doxapramNormal control subjectsHeart rate increasePositron emission tomographyGreater heart rate increasePlacebo dayControl subjectsRespiratory stimulantCingulate gyrusDoxapramNormal volunteersPatientsPanic patientsPanic attacksPanic disorderDoxapram hydrochlorideSeparate daysEmission tomographyInhibitory centersFunctional imagingAmygdala activityCounterbalanced order