2023
Psychedelics, With a Focus on Psilocybin: Issues for the Clinician
Garakani A, Alexander J, Sumner C, Pine J, Gross L, Raison C, Aaronson S, Baron D. Psychedelics, With a Focus on Psilocybin: Issues for the Clinician. Journal Of Psychiatric Practice 2023, 29: 345-353. PMID: 37678363, DOI: 10.1097/pra.0000000000000729.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCommentary: Mania in Medically Ill Patients
Garakani A. Commentary: Mania in Medically Ill Patients. Journal Of Psychiatric Practice 2023, 29: 426-427. PMID: 37678372, DOI: 10.1097/pra.0000000000000731.Commentaries, Editorials and LettersConceptsBipolar disorderBehçet's diseasePatient's symptomsManic symptomsMedical settingsMedically Ill PatientsComprehensive medical evaluationPrimary bipolar disorderSecondary maniaIll patientsMedical illnessMedical floorPsychiatric providersCase reportThorough historyEmergency roomEmergency settingMedical evaluationPsychiatric consultationPsychiatric treatmentPatientsFrontal lobeSymptomsDiseaseDisordersImpact of Substance Use Disorders on Employment for Veterans
Sprong ME, Hollender H, Paul E, Gilbert J, Weber K, Garakani A, Buono FD. Impact of Substance Use Disorders on Employment for Veterans. Psychological Services 2023, 20: 222-231. PMID: 35849362, DOI: 10.1037/ser0000690.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersImpact of SUDMental health conditionsSerious mental health conditionsVocational rehabilitation programCommunity-based employmentMedical conditionsRehabilitation programAlcohol useHealth conditionsVeteransIllicit drugsVR programClosure statusDisordersPresent studyFindingsTransitional work
2022
Commentary: Psychiatric Symptoms Related to Somatic Illness
Garakani A. Commentary: Psychiatric Symptoms Related to Somatic Illness. Journal Of Psychiatric Practice 2022, 28: 514-515. PMID: 36355593, DOI: 10.1097/pra.0000000000000674.Commentaries, Editorials and LettersConceptsAuditory hallucinationsVisual hallucinationsPsychiatric historySomatic illnessPatient's psychiatric historySemicircular canal dehiscencePsychosis presentPsychiatric consultation serviceCharles Bonnet syndromeCanal dehiscenceHypertensive episodesCases of hallucinationsPsychiatric symptomsPsychotic symptomsPsychotic disordersProper diagnosisMedical providersPatientsMedical teamSymptomsConsultation serviceHallucinationsThought disorderIllnessDisordersCommentary: Futility in Psychiatry
Garakani A. Commentary: Futility in Psychiatry. Journal Of Psychiatric Practice 2022, 28: 349-350. PMID: 35797694, DOI: 10.1097/pra.0000000000000649.Commentaries, Editorials and LettersAn umbrella review on the use of antipsychotics in anxiety disorders: A registered report protocol
Garakani A, Freire RC, Buono FD, Thom RP, Larkin K, Funaro MC, Salehi M, Perez-Rodriguez MM. An umbrella review on the use of antipsychotics in anxiety disorders: A registered report protocol. PLOS ONE 2022, 17: e0269772. PMID: 35709149, PMCID: PMC9202921, DOI: 10.1371/journal.pone.0269772.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSelective serotonin reuptake inhibitorsSerotonin-norepinephrine reuptake inhibitorsUse of antipsychoticsLong-term riskAnxiety disordersReuptake inhibitorsUmbrella reviewSide effectsPanic disorderSystematic reviewNon-antipsychotic medicationsUse of quetiapineFirst-line treatmentSerotonin reuptake inhibitorsNorepinephrine reuptake inhibitorsEvidence of efficacyCommon psychiatric disordersTraditional pharmacologic treatmentTreatment of anxietyAdjunctive treatmentPharmacologic treatmentTricyclic antidepressantsAntipsychoticsPsychiatric disordersSocial anxiety disorderCommentary: Diagnostic Challenges
Garakani A. Commentary: Diagnostic Challenges. Journal Of Psychiatric Practice 2022, 28: 270-271. PMID: 35511106, DOI: 10.1097/pra.0000000000000630.Commentaries, Editorials and LettersAn exploratory study of anxiety-motivated gambling in adolescents: Associations with minority status and gambling, health and functioning measures
Cardwell E, Hoff RA, Garakani A, Krishnan-Sarin S, Potenza MN, Zhai ZW. An exploratory study of anxiety-motivated gambling in adolescents: Associations with minority status and gambling, health and functioning measures. Journal Of Psychiatric Research 2022, 151: 445-453. PMID: 35598502, PMCID: PMC9204846, DOI: 10.1016/j.jpsychires.2022.03.052.Peer-Reviewed Original ResearchConceptsProblem gamblingGambling-related measuresRisk/problem gamblingNon-strategic gamblingEmotion dysregulationEmotional dysregulationHealth/functioningHigh school studentsBehavioral correlatesGroup differencesConnecticut high school studentsGamblingRisky behaviorsAnxietyAdolescentsPermissive attitudesFeeling pressureGambling perceptionsMinority statusMotivationExploratory studyDrug useSpecific factorsMinority groupsMeasuresDevelopment and validation of a new scale to measure chronic suicidal ideation: The Chronic Suicidal Ideation Inventory-5 (CSI-5)
Garakani A, Buono FD, Larkin K, Polonsky M, Goldberg JF. Development and validation of a new scale to measure chronic suicidal ideation: The Chronic Suicidal Ideation Inventory-5 (CSI-5). Journal Of Psychiatric Research 2022, 150: 160-164. PMID: 35385817, DOI: 10.1016/j.jpsychires.2022.03.021.Peer-Reviewed Original ResearchConceptsChronic suicidal ideationSuicidal ideationSuicidal thoughtsMood disordersNovel self-report instrumentCronbach's alphaDepression severity scoresYale-Brown ObsessiveIndex hospitalizationInpatient cohortMcDonald's omegaPast suicide attemptsSeverity scoreActivity interferenceSuicide attemptsSuicidal thinkingCompulsive ScaleSelf-report instrumentOne-factor solutionIdeationSignificant Pearson correlationScoresCohortInternal consistencyAlpha
2021
Commentary: Treatment-resistant Depression: Considerations Related to ECT and Ketamine
Garakani A. Commentary: Treatment-resistant Depression: Considerations Related to ECT and Ketamine. Journal Of Psychiatric Practice 2021, 27: 496-497. PMID: 34768276, DOI: 10.1097/pra.0000000000000593.Commentaries, Editorials and LettersConceptsTreatment-resistant depressionElectroconvulsive therapyLiver transplantationChronic treatment-resistant depressionUse of ECTMaintenance electroconvulsive therapyMajor depressive episodeBitemporal treatmentsIntranasal formsIntranasal ketaminePartial responsePrescribed antipsychoticsAdjunctive treatmentAntirejection medicationsChronic migraineMigraine medicationsECT treatmentComorbid migraineDepressive episodePsychotic featuresOrgan transplantationKetamine abuseBrain stimulationClinical considerationsPatientsSelective Serotonin Reuptake Inhibitors: How Long Is Long Enough?
Thom RP, Alexander JL, Baron D, Garakani A, Gross L, Pine JH, Radhakrishnan R, Slaby A, Sumner CR. Selective Serotonin Reuptake Inhibitors: How Long Is Long Enough? Journal Of Psychiatric Practice 2021, 27: 361-371. PMID: 34529602, DOI: 10.1097/pra.0000000000000578.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSelective serotonin reuptake inhibitorsLong-term SSRI useSSRI useEase of titrationFirst-line medicationSerotonin reuptake inhibitorsRisk-benefit ratioMajor depressive disorderGeneral health risksShort-term useClinical practice considerationsDiscontinuation syndromeReuptake inhibitorsSafety profileDepressive disorderPatientsPsychiatric conditionsRelapse preventionMedicationsPossible adverse consequencesSpecial populationsAnxiety disordersTolerabilityPrescribersAdverse consequencesCommentary: Psychiatric Presentations of Nonpsychiatric Illness or Treatment
Garakani A. Commentary: Psychiatric Presentations of Nonpsychiatric Illness or Treatment. Journal Of Psychiatric Practice 2021, 27: 404-405. PMID: 34529609, DOI: 10.1097/pra.0000000000000577.Commentaries, Editorials and LettersConceptsManic symptomsPsychiatric historyPerinatal brain injuryOff-label useExamples of patientsPsychogenic nauseaRefractory nauseaGastroesophageal refluxAtypical presentationMood stabilizersSubdural hematomaCertain patientsMedical historyPsychiatric presentationsBrain injuryVisual hallucinationsMedical disordersPsychiatric symptomsPatientsNonpsychiatric illnessCognitive deficitsSuicidal thinkingSymptomsTraditional treatmentBrain imagingImpact of Childhood Trauma Histories Versus Recent Trauma Symptoms on Affective Lability in Adult Bipolar Disorder.
Garakani A, Buono FD, Larkin K, Goldberg JF. Impact of Childhood Trauma Histories Versus Recent Trauma Symptoms on Affective Lability in Adult Bipolar Disorder. The Journal Of Clinical Psychiatry 2021, 82 PMID: 34406718, DOI: 10.4088/jcp.21br13912.Peer-Reviewed Original ResearchClinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial
Amanat M, Majmaa A, Zarrabi M, Nouri M, Akbari MG, Moaiedi AR, Ghaemi O, Zamani F, Najafi S, Badv RS, Vosough M, Hamidieh AA, Salehi M, Montazerlotfelahi H, Tavasoli AR, Heidari M, Mohebi H, Fatemi A, Garakani A, Ashrafi MR. Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial. Stem Cell Research & Therapy 2021, 12: 439. PMID: 34362453, PMCID: PMC8343813, DOI: 10.1186/s13287-021-02513-4.Peer-Reviewed Original ResearchConceptsModified Ashworth ScaleCerebral palsyMean changeTissue mesenchymal stem cellsPosterior thalamic radiationDiffusion tensor imagingIntrathecal injectionFractional anisotropyCorticospinal tractDouble-blind sham-controlled clinical trialControl groupMesenchymal stem cellsMean GMFM-66 scoresGross Motor Function MeasureSham-controlled clinical trialSham control armSpastic cerebral palsyMotor Function MeasureGMFM-66 scoresTrial registrationThe studyMonths of interventionExperimental groupWhite matter integrityStem cellsCP-QOLCommentary: Diagnostic and Treatment Issues in Psychosis
Garakani A. Commentary: Diagnostic and Treatment Issues in Psychosis. Journal Of Psychiatric Practice 2021, 27: 338-339. PMID: 34398586, DOI: 10.1097/pra.0000000000000562.Commentaries, Editorials and LettersConceptsPsychotic symptomsUse of intranasalWide differential diagnosisFirst-episode schizophreniaMore common conditionsRare presentationPostpartum periodDifferential diagnosisPsychotic episodeCommon conditionSymptomsTreatment issuesPeriodic catatoniaPatientsFirst caseThird caseDiagnosisTreatmentBroad spectrumGaming to relieve tension or anxiety and associations with health functioning, substance use and physical violence in high school students
Garakani A, Zhai ZW, Hoff RA, Krishnan-Sarin S, Potenza MN. Gaming to relieve tension or anxiety and associations with health functioning, substance use and physical violence in high school students. Journal Of Psychiatric Research 2021, 140: 461-467. PMID: 34147933, DOI: 10.1016/j.jpsychires.2021.05.055.Peer-Reviewed Original ResearchConceptsHigh school studentsAcademic performanceSubstance useNegative emotional statesMeasures of demographicsPoor academic performanceProblematic Internet useEmotional statesGaming disorderExtracurricular involvementHealth functioningConnecticut high school studentsDepression symptomsAsian adolescentsAnxietyAdolescentsIntervention strategiesSchool studentsExtracurricular activitiesViolent behaviorGamingPhysical violenceDrug usePhysical fightsAdditional researchThe mediating effects of quality of life, depression, and generalized anxiety on perceived barriers to employment success for people diagnosed with Neurofibromatosis Type 1
Buono FD, Sprong ME, Paul E, Martin S, Larkin K, Garakani A. The mediating effects of quality of life, depression, and generalized anxiety on perceived barriers to employment success for people diagnosed with Neurofibromatosis Type 1. Orphanet Journal Of Rare Diseases 2021, 16: 234. PMID: 34020694, PMCID: PMC8138923, DOI: 10.1186/s13023-021-01866-6.Peer-Reviewed Original ResearchCommentary: Diagnostic Challenges in Evaluating Adolescents
Garakani A. Commentary: Diagnostic Challenges in Evaluating Adolescents. Journal Of Psychiatric Practice 2021, 27: 239-240. PMID: 33939380, DOI: 10.1097/pra.0000000000000553.Commentaries, Editorials and LettersConceptsDiagnostic challengeConstellation of symptomsProminent mood symptomsPosttraumatic stress disorderFemale patientsTrauma-related symptomsMedication treatmentAntipsychotic medicationAdolescent patientsUnnecessary treatmentVisual hallucinationsDifferential diagnosisPatient reportsTerms of stigmaMood symptomsDepressive symptomsPsychotic symptomsSide effectsPatientsPsychotic disordersSuicidal ideasFull differential diagnosisAuditory hallucinationsCotard's syndromeIncorrect diagnosisNeurological manifestations as the predictors of severity and mortality in hospitalized individuals with COVID-19: a multicenter prospective clinical study
Amanat M, Rezaei N, Roozbeh M, Shojaei M, Tafakhori A, Zoghi A, Darazam IA, Salehi M, Karimialavijeh E, Lima BS, Garakani A, Vaccaro A, Ramezani M. Neurological manifestations as the predictors of severity and mortality in hospitalized individuals with COVID-19: a multicenter prospective clinical study. BMC Neurology 2021, 21: 116. PMID: 33726699, PMCID: PMC7960879, DOI: 10.1186/s12883-021-02152-5.Peer-Reviewed Original ResearchConceptsShortness of breathPredictors of severityTaste dysfunctionNeurological manifestationsNeurological symptomsSevere casesCOVID-19Multicenter prospective clinical studyMulti-center prospective studyHyposmia/anosmiaGuillain-Barré syndromeWeeks of dischargeProspective clinical studyCommon neurological symptomsTime of admissionNon-neurological manifestationsCoronavirus disease 2019COVID-19 diseaseCerebrovascular eventsChest tightnessStatus epilepticusEligible casesNeurological findingsProspective studyMild headacheCommentary on 2 Cases of Neuropsychiatric Symptoms Occurring in Association With COVID-19
Garakani A. Commentary on 2 Cases of Neuropsychiatric Symptoms Occurring in Association With COVID-19. Journal Of Psychiatric Practice 2021, 27: 145-146. PMID: 33656822, DOI: 10.1097/pra.0000000000000527.Commentaries, Editorials and LettersConceptsPositive COVID-19 testCOVID-19 infectionNeuropsychiatric symptomsPsychotic symptomsSuicide attemptsCoronavirus disease 2019 (COVID-19) infectionCOVID-19Recent respiratory illnessDisease 2019 infectionAcute psychotic symptomsHistory of depressionInpatient psychiatric unitMiddle-age menSerious suicide attemptsCOVID-19 testPatient's symptomsNeuropsychiatric sequelaeRespiratory illnessAntipsychotic medicationPatient's psychosisPsychotic episodeMood symptomsNeurological etiologyPsychiatric historyPsychiatric unit