2020
Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency
Bai H, Sadaghianloo N, Gorecka J, Liu S, Ono S, Ramachandra AB, Bonnet S, Mazure NM, Declemy S, Humphrey JD, Dardik A. Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. Science Translational Medicine 2020, 12 PMID: 32817365, PMCID: PMC7705473, DOI: 10.1126/scitranslmed.aax7613.Peer-Reviewed Original ResearchConceptsArteriovenous fistulaHemodialysis accessNeointimal hyperplasiaEndothelial nitric oxide synthaseDurable surgical optionUremic male ratsRadial-cephalic arteriovenous fistulaKruppel-like factor 2Nitric oxide synthasePeak systolic velocityLong-term patencyReintervention rateSecondary patencyImproved hemodynamicsFemale patientsReimplantation techniqueSurgical optionsSystolic velocityMale ratsOxide synthaseFistula modelPatencyHemodynamicsDifferent hemodynamicsFemale animals
1998
Shear stress and the endothelium.
Ballermann B, Dardik A, Eng E, Liu A. Shear stress and the endothelium. Kidney International Supplement 1998, 67: s100-8. PMID: 9736263, DOI: 10.1046/j.1523-1755.1998.06720.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEndothelial nitric oxide synthaseChronic shear stressEndothelial cellsBlood flowGrowth factorWall distentionNitric oxide synthaseTranscription factor nuclear factorPlatelet-derived growth factorVascular endothelial cellsAcute shear stressInflammatory cytokinesMCP-1Oxide synthaseICAM-1Cyclooxygenase IIAcute releaseStructural remodelingTissue factorNitric oxideNuclear factorTransmural pressureC-fosVascular prosthesesEvidence of differentiationShear stress and the endothelium
Ballermann B, Dardik A, Eng E, Liu A. Shear stress and the endothelium. Kidney International 1998, 54: s100-s108. DOI: 10.1046/j.1523-1755.1998.06720.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEndothelial nitric oxide synthaseChronic shear stressEndothelial cellsBlood flowGrowth factorWall distentionTranscription factor nuclear factorNitric oxide synthasePlatelet-derived growth factorVascular endothelial cellsAcute shear stressInflammatory cytokinesMCP-1Oxide synthaseICAM-1Cyclooxygenase IIAcute releaseStructural remodelingTissue factorNitric oxideNuclear factorTransmural pressureC-fosRapid cytoskeletal remodelingVascular prostheses