2021
The mutational landscape of human somatic and germline cells
Moore L, Cagan A, Coorens T, Neville M, Sanghvi R, Sanders M, Oliver T, Leongamornlert D, Ellis P, Noorani A, Mitchell T, Butler T, Hooks Y, Warren A, Jorgensen M, Dawson K, Menzies A, O’Neill L, Latimer C, Teng M, van Boxtel R, Iacobuzio-Donahue C, Martincorena I, Heer R, Campbell P, Fitzgerald R, Stratton M, Rahbari R. The mutational landscape of human somatic and germline cells. Nature 2021, 597: 381-386. PMID: 34433962, DOI: 10.1038/s41586-021-03822-7.Peer-Reviewed Original ResearchConceptsCell typesMutational landscapeRate of mutationLow rate of cell divisionRate of cell divisionBasal spermatogoniaGermline cellsGenetic variationCell divisionHuman cellsMutational signaturesGermlineAcquired mutationsMutationsSpermatogoniaHuman populationCellsIndividual's lifetimeSBS5/40SpermSBS18Stem cellsSBS1LandscapeType
2000
Residents’ medical information needs in clinic: are they being met?
Green M, Ciampi M, Ellis P. Residents’ medical information needs in clinic: are they being met? The American Journal Of Medicine 2000, 109: 218-223. PMID: 10974185, DOI: 10.1016/s0002-9343(00)00458-7.Peer-Reviewed Original ResearchConceptsClinical questionsPatient encountersUnanswered clinical questionsEvidence-based medicineNew clinical questionsInternal medicine programsMultivariable analysisOutpatient clinicMedical informationFrequent reasonTeaching clinicClinic sessionsLack of timeLevel of agreementClinicCommon typeMalpractice exposureMedicine programsPatientsMissed opportunityOriginal articlesSeries of statementsResidentsTherapyPhysicians