2021
Optimal Management for Residual Disease Following Neoadjuvant Systemic Therapy
Foldi J, Rozenblit M, Park TS, Knowlton CA, Golshan M, Moran M, Pusztai L. Optimal Management for Residual Disease Following Neoadjuvant Systemic Therapy. Current Treatment Options In Oncology 2021, 22: 79. PMID: 34213636, DOI: 10.1007/s11864-021-00879-4.Peer-Reviewed Original ResearchConceptsPathologic complete responseResidual cancerClinical trialsAdjuvant therapyExcellent long-term disease-free survivalLong-term disease-free survivalAxillary lymph node dissectionHuman epidermal growth factor receptor 2Early-stage breast cancerEpidermal growth factor receptor 2Post-mastectomy breastSystemic adjuvant therapyInternal mammary nodesLymph node dissectionNeoadjuvant systemic therapyDisease-free survivalGrowth factor receptor 2Minimal residual disease monitoringRecurrence-free survivalType of surgeryPivotal clinical trialsOngoing clinical trialsFactor receptor 2Residual disease monitoringAccurate prognostic estimates
2011
Surgical Margins and the Risk of Local-Regional Recurrence (LRR) following Mastectomy for Early-stage Breast Cancer
Childs S, Chen Y, Golshan M, Duggan M, Pochebit S, Wong J, Harris J, Bellon J. Surgical Margins and the Risk of Local-Regional Recurrence (LRR) following Mastectomy for Early-stage Breast Cancer. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s233-s234. DOI: 10.1016/j.ijrobp.2011.06.436.Peer-Reviewed Original ResearchSurgical margins and the risk of local-regional recurrence (LRR) following mastectomy for early-stage breast cancer.
Childs S, Chen Y, Pochebit S, Golshan M, Duggan M, Wong J, Harris J, Bellon J. Surgical margins and the risk of local-regional recurrence (LRR) following mastectomy for early-stage breast cancer. Journal Of Clinical Oncology 2011, 29: 95-95. DOI: 10.1200/jco.2011.29.27_suppl.95.Peer-Reviewed Original ResearchLocal-regional recurrenceRisk of LRRInvasive diseaseSurgical marginsSuperficial marginsDeep marginBreast cancerEarly-stage breast cancerPositive axillary nodesClose surgical marginsDistant metastasis rateKaplan-Meier methodPost-mastectomy radiationDeep surgical marginsInvasive breast cancerLRR ratePositive nodesAxillary nodesFirst recurrenceLymphovascular invasionPure DCIST3 tumorsConsecutive womenMedian ageMetastasis rate
2009
Factors affecting surgical decision-making in patients undergoing BRCA1/2 testing at breast cancer diagnosis.
Stadler Z, Stoeckert K, Perez A, Regan M, Golshan M, Garber J. Factors affecting surgical decision-making in patients undergoing BRCA1/2 testing at breast cancer diagnosis. Cancer Research 2009, 69: 1095. DOI: 10.1158/0008-5472.sabcs-1095.Peer-Reviewed Original ResearchBilateral mastectomyFamily cancer historyPre-test probabilityBC patientsBRCA1/2 mutationsBreast MRIBreast conservationIndependent predictorsSurgical treatmentCancer historyBC diagnosisBreast cancerEarly-stage breast cancerDana-Farber Cancer InstituteLogistic regressionPositive genetic test resultAbnormal MRI resultsDeleterious BRCA1/2 mutationsAbnormal MRI findingsDefinitive surgical treatmentBRCA1/2 germline mutationsTest-negative patientsTime of diagnosisStage breast cancerStrong independent predictor