Research/Projects

Some of the ongoing projects and topics of interest are:

• Fundamental studies in neuroinflammatory responses, with a broad interest in inflammatory responses across different types of cerebrovascular disease
• Macrophages and microglial responses, including similarities and differences across phases of injury and recovery
• Developing methods for making in vitro culture systems and stimulations that more accurately model the complex stimuli cells experience in the brain
• Investigations into morbidities, including aging and sex differences, diabetes, and infections, and how these affect immune responses to brain injury
• Metabolic pathways and the determination and manipulation of leukocyte inflammatory states
• Testing of potential therapeutics for the treatment of stroke and intracerebral hemorrhage
• Translational studies using clinical trial data, patient samples, biorepositories, and ex vivo analyses of patient samples that guide in vitro and experimental modeling of leukocyte responses in human cellular assays.