2011
Integration of tight junctions and claudins with the barrier functions of the retinal pigment epithelium
Rizzolo LJ, Peng S, Luo Y, Xiao W. Integration of tight junctions and claudins with the barrier functions of the retinal pigment epithelium. Progress In Retinal And Eye Research 2011, 30: 296-323. PMID: 21704180, DOI: 10.1016/j.preteyeres.2011.06.002.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumOuter retinaPigment epitheliumTight junctionsBarrier functionOuter blood-retinal barrierBlood-retinal barrierHuman retinal pigment epitheliumBlood-tissue barriersTight junctional proteinsPhotoreceptor layerNeural retinaMetabolic alterationsRetinaEpitheliumClaudin compositionTransepithelial diffusionStem cellsJunctional proteinsClaudins
2007
Development and Role of Tight Junctions in the Retinal Pigment Epithelium
Rizzolo LJ. Development and Role of Tight Junctions in the Retinal Pigment Epithelium. International Review Of Cytology 2007, 258: 195-234. PMID: 17338922, DOI: 10.1016/s0074-7696(07)58004-6.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsHumansMembrane ProteinsMolecular Sequence DataPigment Epithelium of EyeTight JunctionsConceptsRetinal pigment epitheliumPigment epitheliumNeural retinaTight junctionsOuter blood-retinal barrierBlood-retinal barrierSlower time courseEpitheliumCell proliferationTissue-specific propertiesTransepithelial diffusionTime courseRetinaParacellular diffusionPhysiological roleEpithelial monolayersSolid tissuesParacellular spaceApical surfaceCulture system
2002
Claudin 5 Is Transiently Expressed During the Development of the Retinal Pigment Epithelium
Kojima S, Rahner C, Peng S, Rizzolo L. Claudin 5 Is Transiently Expressed During the Development of the Retinal Pigment Epithelium. The Journal Of Membrane Biology 2002, 186: 81-88. PMID: 11944085, DOI: 10.1007/s00232-001-0137-7.Peer-Reviewed Original ResearchConceptsReverse transcriptase-polymerase chain reactionRetinal pigment epitheliumClaudin-5Chick retinal pigment epitheliumPigment epitheliumTranscriptase-polymerase chain reactionEmbryonic day 14Tight junctionsSemiquantitative RT-PCRExpression of claudinsEmbryonic day 10Northern blottingNeural retinaDay 14Semi-quantitative RT-PCRDay 10Claudin-3RPE developmentPeak levelsDay 7 embryosChoroid layerPrimary culturesChain reactionEpitheliumBlotting
1998
Protein-Binding Domains of the Tight Junction Protein, ZO-2, Are Highly Conserved between Avian and Mammalian Species
Collins J, Rizzolo L. Protein-Binding Domains of the Tight Junction Protein, ZO-2, Are Highly Conserved between Avian and Mammalian Species. Biochemical And Biophysical Research Communications 1998, 252: 617-622. PMID: 9837755, DOI: 10.1006/bbrc.1998.9710.Peer-Reviewed Original ResearchConceptsProtein-binding domainsSrc homology 3ZO-2ZO-3Homologous domainsMAGUK protein familyDistinct PDZ domainsProtein binding domainsZO-1Apical junctional complexHomology 3PDZ domainProtein familySH3 domainAcidic domainEvolutionary pressureMammalian speciesJunctional complexesEmbryonic chicken retinaJunction proteinsTight junctionsDifferent functionsProteinTight junction proteinsSequence