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Pierce Lab

Understanding blood vessel function in critical illness

Our passion is to understand blood vessel dysfunction in the setting of critical illness. Blood vessels, and the endothelial cells that line them, extend to within micron of all the cells in the human body. Blood vessels regulate blood volume, flow and fluidity as well as immune and platelet activation. To understand how these processes break down in the setting of critical illness we must understand the fundamental biology of endothelial cells and care for the sickest patients.