Publications

2026

Brief Report: Is once daily enough? Assessing the impact of timing of methadone dose on pain sensitivity via quantitative sensory testing in persons with opioid use disorder
Costa G, Riggione C, Meyerovich J, Barry D, De Aquino J. Brief Report: Is once daily enough? Assessing the impact of timing of methadone dose on pain sensitivity via quantitative sensory testing in persons with opioid use disorder. American Journal On Addictions 2026 PMID: 42046174, PMCID: PMC13132031, DOI: 10.1111/ajad.70162.
Peer-Reviewed Original Research
Concepts
Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies
Costa G, Cerezo-Matias M, Funaro M, Bagdas D, Kaye A, Krystal J, Petrakis I, De Aquino J. Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies. Molecular Psychiatry 2026, 31: 3849-3871. PMID: 41760917, PMCID: PMC13269127, DOI: 10.1038/s41380-026-03523-5.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
This study investigates targeting the endocannabinoid system for alcohol use disorder, finding promising preclinical results for cannabidiol and CB1 receptor modulators, but inconsistent human trial outcomes highlight the need for better-designed clinical studies.
Full Summary
Psychedelic‐assisted therapy for substance use disorders: Between urgency and uncertainty
De Aquino J. Psychedelic‐assisted therapy for substance use disorders: Between urgency and uncertainty. American Journal On Addictions 2026, 35: 317-318. PMID: 41742736, DOI: 10.1111/ajad.70128.
Peer-Reviewed Original Research
Characteristics of United States Food and Drug Administration Drug Recalls Involving Opioid Medications, 2002–2025
Nunes J, Costa G, De Aquino J. Characteristics of United States Food and Drug Administration Drug Recalls Involving Opioid Medications, 2002–2025. Pharmacoepidemiology And Drug Safety 2026, 35: e70341. PMID: 41725568, DOI: 10.1002/pds.70341.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Addiction research and national resilience: Protecting surveillance, treatment development, and integrated care
Nunes J, De Aquino J. Addiction research and national resilience: Protecting surveillance, treatment development, and integrated care. Drug And Alcohol Dependence 2026, 279: 113002. DOI: 10.1016/j.drugalcdep.2025.113002.
Peer-Reviewed Original Research
Concepts

2025

2024

See All Publications

Publications

2026

Brief Report: Is once daily enough? Assessing the impact of timing of methadone dose on pain sensitivity via quantitative sensory testing in persons with opioid use disorder

Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies

Psychedelic‐assisted therapy for substance use disorders: Between urgency and uncertainty

Characteristics of United States Food and Drug Administration Drug Recalls Involving Opioid Medications, 2002–2025

Addiction research and national resilience: Protecting surveillance, treatment development, and integrated care

2025

Exploring the effects of cannabidiol on pain sensitivity using quantitative sensory testing among individuals receiving methadone or buprenorphine for opioid use disorder: an open-label, proof-of-concept study

Differences in diagnosis and treatment across racial–ethnic groups with co-occurring chronic pain and opioid use disorder: a scoping review

Expanding Access to Buprenorphine and Methadone: Global Perspectives and Policy Recommendations

Tobacco use Disorder and Chronic Pain: a Narrative Review of Integrated Treatment Approaches, Underlying Mechanisms, and Future Research Directions

Tobacco–cannabis co‐use in adults ≥50: Trends, medical marijuana laws, and cessation implications—Letter to the Editor

Quantitative sensory testing of pain in persons with opioid use disorder on opioid agonist treatment: a scoping review

Cannabis use frequency is associated with emotion dysregulation among persons receiving long-term opioid therapy for chronic pain: A psychophysiological study

The Role of Childhood Trauma in Chronic Pain and Substance Use Among Individuals Receiving Methadone Treatment for Opioid Use Disorder

Psychedelic drugs for the treatment of substance use disorders

Pain interference, alcohol use, and metabolic health: Insights from a nationally representative study

Letter to the Editor: Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-Blind Randomized Controlled Trial

Exploring the Addictive Potential of Tranylcypromine

Response to the letter to the editor

The bidirectional relationship between pain and tobacco use: Insights from the longitudinal Population Assessment of Tobacco and Health (PATH) study

Buprenorphine versus full agonist opioids for acute postoperative pain management: an infographic

Buprenorphine versus full agonist opioids for acute postoperative pain management: a systematic review and meta-analysis of randomized controlled trials

2024

Navigating new norms: Addiction specialists' perspectives on opioid use disorder treatments and policy challenges in the fentanyl era

Editorial for the themed issue: Addressing the dual challenges of opioid use disorder and chronic pain in the context of the opioid crisis

The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review

We Need to Rethink Our Strategy on Cannabis in the Overdose Crisis