Nihar Desai, MD, MPH
Associate Professor of Medicine (Cardiovascular Medicine)Cards
About
Titles
Associate Professor of Medicine (Cardiovascular Medicine)
Biography
Nihar R. Desai, MD, MPH is an Associate Professor of Medicine and Vice Chief of the Section of Cardiovascular Medicine at Yale University School of Medicine, an Investigator at the Center for Outcomes Research and Evaluation, and Executive Director for Bundled Payments and Clinical Service Line Operations at the Yale New Haven Health System. His interests focus on cardiovascular health services and comparative effectiveness research, examining patterns of care, identifying opportunities to improve clinical outcomes, and evaluating the impact of novel care delivery systems on cost and quality. In addition, he serves as a clinical consultant on the CMS acute myocardial infarction, heart failure, and coronary artery bypass graft surgery readmission and mortality measures. He graduated with highest honors from Lehigh University before completing an internship in the Clinton White House. He then attended the University of Connecticut School of Medicine where he received his Doctorate in Medicine and the Harvard School of Public Health where he received his Master’s in Public Health. Dr. Desai completed his residency training in Internal Medicine as well as his clinical fellowship in Cardiovascular Medicine at Brigham and Women’s Hospital and Harvard Medical School. He then completed a research fellowship at the TIMI Study Group with Dr. Eugene Braunwald. His scholarly work has been published in New England Journal of Medicine, Journal of the American Medical Association, Circulation, and the Journal of the American College of Cardiology.
Appointments
Cardiovascular Medicine
Associate Professor on TermPrimary
Other Departments & Organizations
- Cardiovascular Medicine
- Center for Outcomes Research & Evaluation (CORE)
- Clinical and Translational Research Accelerator (CTRA)
- Internal Medicine
- Yale Medicine
- Yale New Haven Health System
- Yale Ventures
- Yale-BI Biomedical Data Science Fellowship
Education & Training
- Fellowship
- Brigham & Women's Hospital (2013)
- Residency
- Brigham & Women's Hospital (2009)
- MD
- University of Connecticut School of Medicine (2006)
- MPH
- Harvard School of Public Health (2005)
Research
Publications
2026
Timing of Mechanical Circulatory Support and In-Hospital Mortality in Patients With Cardiogenic Shock
Garimella S, Caraballo C, Victoria-Castro A, Safiriyu I, Banna S, Mullan C, El Zarif T, Callegari S, Abushouk A, Jacobs M, Elliott A, Katz J, Gage A, Desai N, Ali T, Miller P. Timing of Mechanical Circulatory Support and In-Hospital Mortality in Patients With Cardiogenic Shock. Mayo Clinic Proceedings 2026 PMID: 42484571, DOI: 10.1016/j.mayocp.2026.02.017.Peer-Reviewed Original ResearchA Decade of the YODA Project: Advancing Clinical Trial Data Sharing through Transparency, Independence, and Collaboration
Taherifard E, Ritchie J, Willeford M, Bamford S, Berlin J, Childers K, Desai N, Gross C, Hewens D, Lehman R, Lins P, Morris S, Sargood T, Wallach J, Waldstreicher J, Krumholz H, Ross J. A Decade of the YODA Project: Advancing Clinical Trial Data Sharing through Transparency, Independence, and Collaboration. Scientific Data 2026 PMID: 42436174, DOI: 10.1038/s41597-026-07854-4.Peer-Reviewed Original ResearchLow‐Density Lipoprotein Cholesterol Lowering With Inclisiran Plus Usual Care in Recent Acute Coronary Syndrome: VICTORION‐INCEPTION, a Randomized, Controlled, Open‐Label Trial
Knowlton K, Navar A, Anderson J, Brown A, Muhlestein J, Kleeman K, Sarwat S, Abbas C, Ramirez M, Grines C, Abo‐Auda W, Desai N. Low‐Density Lipoprotein Cholesterol Lowering With Inclisiran Plus Usual Care in Recent Acute Coronary Syndrome: VICTORION‐INCEPTION, a Randomized, Controlled, Open‐Label Trial. Journal Of The American Heart Association 2026, 15: e043655. PMID: 42132192, PMCID: PMC13279551, DOI: 10.1161/jaha.125.043655.Peer-Reviewed Original ResearchPodcast Episode 1: A Pragmatic Overview of Heart Failure in Patients with Diabetes for Endocrinologists, Primary Care Physicians and Noncardiologist Clinicians
Desai N, Inzucchi S, Wright E. Podcast Episode 1: A Pragmatic Overview of Heart Failure in Patients with Diabetes for Endocrinologists, Primary Care Physicians and Noncardiologist Clinicians. Diabetes Therapy 2026, 17: 799-806. PMID: 41984374, PMCID: PMC13253936, DOI: 10.1007/s13300-026-01855-7.Commentaries, Editorials and LettersPodcast Episode 3: How Can Physicians Work Collaboratively to Improve Cardiovascular Outcomes in Patients with Type 2 Diabetes?
Desai N, Inzucchi S, Wright E. Podcast Episode 3: How Can Physicians Work Collaboratively to Improve Cardiovascular Outcomes in Patients with Type 2 Diabetes? Diabetes Therapy 2026, 17: 815-822. PMID: 41984375, PMCID: PMC13253934, DOI: 10.1007/s13300-026-01857-5.Commentaries, Editorials and LettersPodcast Episode 2: Heart Failure Management in Patients with Diabetes for Endocrinologists, Primary Care Physicians, and Noncardiologist Clinicians: Focus on SGLT2 Inhibitors
Desai N, Inzucchi S, Wright E. Podcast Episode 2: Heart Failure Management in Patients with Diabetes for Endocrinologists, Primary Care Physicians, and Noncardiologist Clinicians: Focus on SGLT2 Inhibitors. Diabetes Therapy 2026, 17: 807-814. PMID: 41984371, PMCID: PMC13253893, DOI: 10.1007/s13300-026-01856-6.Commentaries, Editorials and LettersHospitalization and Emergency Department Costs in Patiromer and Sodium Zirconium Cyclosilicate Users.
Desai N, Thakar C, Desai T, Soro M, Budden J, Kleinman N. Hospitalization and Emergency Department Costs in Patiromer and Sodium Zirconium Cyclosilicate Users. Kidney360 2026 PMID: 41920707, DOI: 10.34067/kid.0000001195.Peer-Reviewed Original ResearchDo myelodysplasia-related gene mutations alter transplant decisions in NPM1-mutated acute myeloid leukemia? Comment on: "Prognostic implications of myelodysplasiarelated gene mutations in NPM1-mutated acute myeloid leukemia: a systematic review and meta-analysis".
Desai N, Mattsson J. Do myelodysplasia-related gene mutations alter transplant decisions in NPM1-mutated acute myeloid leukemia? Comment on: "Prognostic implications of myelodysplasiarelated gene mutations in NPM1-mutated acute myeloid leukemia: a systematic review and meta-analysis". Haematologica 2026 PMID: 41885021, DOI: 10.3324/haematol.2026.300857.Peer-Reviewed Original ResearchPatiromer for Patients with Heart Failure at Risk of Hyperkalemia: CARE-HK in HF Registry
Cantu-Martinez O, Greene S, Chinnakondepalli K, Anker S, Bozkurt B, Butler J, Cleland J, Desai N, Grobbee D, Kelepouris E, Rosano G, Kempf T, Schulz M, Brandes C, Donachie V, Sauer A. Patiromer for Patients with Heart Failure at Risk of Hyperkalemia: CARE-HK in HF Registry. Journal Of Cardiac Failure 2026 PMID: 41903909, DOI: 10.1016/j.cardfail.2026.03.025.Peer-Reviewed Original ResearchResidual Risk of Hyperkalemia Among Patients with Heart Failure Treated with Both SGLT2i and ARNI
Greene S, Patel S, Chinnakondepalli K, Anker S, Böhm M, Bozkurt B, Butler J, Cleland J, Coats A, Desai N, Donachie V, Kelepouris E, Rosano G, Brandes C, Sauer A. Residual Risk of Hyperkalemia Among Patients with Heart Failure Treated with Both SGLT2i and ARNI. Journal Of Cardiac Failure 2026 PMID: 41895677, DOI: 10.1016/j.cardfail.2026.03.018.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Pragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor Antagonists (PROMPT-MRA)
IRB ID2000030513RoleSub InvestigatorPrimary Completion Date12/01/2023Recruiting ParticipantsGenderBothAge18+ years
Clinical Care
Overview
Nihar Desai, MD, MPH, is a cardiovascular medicine specialist, treating patients with complex cardiovascular conditions, including acute coronary syndromes, heart failure, valvular heart disease, and arrhythmias.
Dr. Desai’s research explores opportunities to improve the quality of care, the impact of decision support tools on care patterns, and how different models of care affect quality, outcomes, and cost of care. He leads clinical trials and real world studies using administrative and clinical datasets to conduct hypothesis driven research of importance to patients, providers, payers, and policymakers.
Dr. Desai is an associate professor of medicine at Yale School of Medicine.
Clinical Specialties
News
News
- October 24, 2024
New Analytics Center for Cardiovascular Medicine
- July 24, 2024
Yale Department of Internal Medicine Faculty Promotions and Appointments (July 2024)
- April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions
- March 29, 2024Source: The New York Times
Heart Pump Is Linked to 49 Deaths, the F.D.A. Warns
Get In Touch
Contacts
Cardiovascular Medicine
15 York Street, PO Box 208017
New Haven, CT 06520-8017
United States
Administrative Support
Locations
Patient Care Locations
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