Aydin Arici, MD
Professor of Obstetrics, Gynecology, and Reproductive SciencesCards
About
Research
Overview
Medical Research Interests
Chemokines; Cytokines; Endometriosis; Gynecology; Infertility; Obstetrics; Peritoneal Cavity; Reproductive Techniques
Publications
2019
Long‐term GnRH agonist therapy before in vitro fertilization (IVF) for improving fertility outcomes in women with endometriosis
Jaafar S, Sallam H, Arici A, Garcia‐Velasco J, Abou‐Setta A. Long‐term GnRH agonist therapy before in vitro fertilization (IVF) for improving fertility outcomes in women with endometriosis. Cochrane Database Of Systematic Reviews 2019, 2019 PMCID: PMC6353287, DOI: 10.1002/14651858.cd013240.Peer-Reviewed Original Research
2018
EndoART: A proposed randomized controlled trial on endometriomas in assisted reproductive technologies, comparing the effect of no intervention, surgery, and prolonged GnRH downregulation on pregnancy rates
Tomassetti C, Adamson D, Arici A, Canis M, Hompes P, Hummelshoj L, Mol B, Nardo L, Rombauts L, D’Hooghe T. EndoART: A proposed randomized controlled trial on endometriomas in assisted reproductive technologies, comparing the effect of no intervention, surgery, and prolonged GnRH downregulation on pregnancy rates. Journal Of Endometriosis And Pelvic Pain Disorders 2018, 10: 158-173. DOI: 10.1177/2284026518784236.Peer-Reviewed Original ResearchClinical pregnancy rateLive birth ratePregnancy rateART pregnancy rateFresh ART cyclesOvarian surgeryART cyclesOutcome measuresCumulative clinical pregnancy rateSecondary outcome measuresPrimary outcome measureMulti-center trialReproductive technologiesHigher pregnancy rateBirth rateQuality of lifeDifferent treatment groupsPelvic painOvarian reserveHormonal suppressionClinical managementTreatment groupsMatter of debateSurgeryGnRHTumor necrosis factor alfa and interleukin 1 alfa induced phosphorylation and degradation of inhibitory kappa B alpha are regulated by estradiol in endometrial cells
Arlıer S, Kayışlı Ü, Arıcı A. Tumor necrosis factor alfa and interleukin 1 alfa induced phosphorylation and degradation of inhibitory kappa B alpha are regulated by estradiol in endometrial cells. Journal Of Turkish Society Of Obstetric And Gynecology 2018, 15: 50-59. PMID: 29662717, PMCID: PMC5894537, DOI: 10.4274/tjod.47700.Peer-Reviewed Original ResearchEndometrial cellsNormal endometriumEctopic endometriumInhibitory kappa B-alphaTranscription factor nuclear factor kappa BInhibitory kappa B (IκBα) proteinMonocyte chemoattractant protein-1Ectopic endometrial cellsHomologous eutopic endometriumNuclear factor kappa BCultured endometrial cellsEffects of estradiolNecrosis factor alfaChemoattractant protein-1Human endometrial cellsRegulation of chemokinesTumor necrosis factorFactor kappa BKappa B alphaUterine endometrial cellsEutopic endometriumInflammatory responseNecrosis factorEndometriumKappa B
2012
High rate of allergies among women with endometriosis
Matalliotakis I, Cakmak H, Matalliotakis M, Kappou D, Arici A. High rate of allergies among women with endometriosis. Journal Of Obstetrics And Gynaecology 2012, 32: 291-293. PMID: 22369407, DOI: 10.3109/01443615.2011.644358.Peer-Reviewed Original ResearchConceptsAllergic rhinitisFamily historyYale University HospitalPerennial allergic rhinitisAutoimmune inflammatory diseaseStage of endometriosisPrevalence of allergyMain outcome measuresPositive family historyEndometriosis stageAllergic diseasesAutoimmune disordersMedical filesUniversity HospitalInflammatory diseasesPositive historyOutcome measuresEndometriosisAllergyControl groupAsthmaOverall riskWomenRhinitisMedications18 Women's Health
Rackow B, Arici A, Martin V, Reid R, Lewis J, Borgen P, Herndon E, Harnisch D, Silasi D, Azodi M, Olive D, Williams S, Burd I, Scheib S, Boyle K, Rose P, Bagley A, Trent M, Freeman E, Aeby T, Dantas S, Davidson S, Hudak C. 18 Women's Health. 2012, 981-1028. DOI: 10.1016/b978-1-4557-0738-6.00018-8.Peer-Reviewed Original Research
2011
Endoplasmic reticulum homeostasis is crucial for in vitro blastocyst development
Bozkurt I, Basar M, Tekmen I, Arici A, Kayisli U. Endoplasmic reticulum homeostasis is crucial for in vitro blastocyst development. Fertility And Sterility 2011, 96: s80. DOI: 10.1016/j.fertnstert.2011.07.310.Peer-Reviewed Original ResearchEndoplasmic reticulum (ER) homeostasis is cycle-dependent and the inflammatory cytokines TNF-α and ILI-1β induce er stress by regulating BIP expression in human endometrial ENDOTHELIAL CELLS
Ocak N, Guzel E, Bozkurt I, Bagriyanik A, Arici A, Kayisli U. Endoplasmic reticulum (ER) homeostasis is cycle-dependent and the inflammatory cytokines TNF-α and ILI-1β induce er stress by regulating BIP expression in human endometrial ENDOTHELIAL CELLS. Fertility And Sterility 2011, 96: s27. DOI: 10.1016/j.fertnstert.2011.07.110.Peer-Reviewed Original ResearchImplantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility
Matalliotakis I, Sakkas D, Illuzzi J, Matalliotaki C, Arici A. Implantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility. Journal Of Endometriosis And Pelvic Pain Disorders 2011, 3: 86-92. DOI: 10.5301/je.2011.8528.Peer-Reviewed Original ResearchTubal factor infertilityMale infertilityTubal infertilityInfertility groupEndometriosis groupFactor infertilityImplantation rateAge-matched control groupMale infertility groupTubal infertility groupICSI treatment cyclesReduced pregnancy rateMethods Five hundredDelivery rateNumber of embryosConsecutive IVFIVF treatmentIVF programPregnancy rateUterine receptivityEndometriosisTreatment cyclesControl groupInfertilityPatientsEndometriosis: Pathogenesis and Management of Pain
Kulp J, Arici A. Endometriosis: Pathogenesis and Management of Pain. 2011, 40-49. DOI: 10.1002/9781444391855.ch4.Peer-Reviewed Original ResearchNonsteroidal anti-inflammatory medicationsGonadotropin-releasing hormone agonistAnti-inflammatory medicationsChronic pelvic painDysfunctional immune responseManagement of painOral contraceptive pillsSymptoms of endometriosisTime of laparoscopyEtiology of endometriosisSymptomatic endometriomasPelvic painSurgical treatmentHormone agonistMedical managementRetrograde menstruationContraceptive pillsLikely multifactorialImmune responseCommon conditionEndometriosisGenetic predispositionPainStem cellsPopulation of lesions
2010
Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results
Kutlu P, Atvar O, Vanlioglu O, Kutlu U, Arici A, Yilmaz S, Yilmaz E, Delikara N, Bener F, Kamar A, Alpak O, Ozekici U. Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results. Reproductive BioMedicine Online 2010, 22: 208-214. PMID: 21195669, DOI: 10.1016/j.rbmo.2010.10.007.Peer-Reviewed Original ResearchConceptsMultiple pregnancy ratePregnancy rateAge groupsSingle embryo transfer policyOverall populationClinical pregnancy rateSecond treatment cycleAssisted reproduction outcomesYears of ageNumber of embryosDifferent age groupsClinical pregnancyMulticentre studyMultiple pregnanciesReproduction treatmentTreatment cyclesReproduction outcomesOlder agePregnancyOutcomesFurther investigationSignificant declineFurther cyclesAgeGroup
Clinical Trials
Current Trials
Fibroids and Unexplained Infertility Treatment with Epigallocatechin Gallate; A Natural CompounD in Green Tea (FRIEND)
HIC ID2000032075RoleSub InvestigatorPrimary Completion Date05/31/2025Recruiting ParticipantsPre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis (PREGnant)
HIC ID2000027121RoleSub InvestigatorPrimary Completion Date09/30/2024Recruiting ParticipantsGenderFemaleAge18 years - 38 years
Clinical Care
Overview
Aydin Arici, MD, is a reproductive endocrinologist and focuses on a variety of health areas, including in vitro fertilization (IVF), infertility, endometriosis, implantation, myomas, and uterine anomalies.
Dr. Arici is a professor of obstetrics, gynecology, and reproductive sciences at Yale School of Medicine. His research interests encompass a broad range of topics, including chemokines, cytokines, and their roles in gynecology and infertility. He is focused on understanding the complexities of endometriosis and its impact on reproductive health, as well as exploring innovative reproductive techniques.
Dr. Arici earned his medical degree from Istanbul Medical School in Turkey. He completed his residency in obstetrics and gynecology at Columbia University, College of Physicians and Surgeons in New York City, and further specialized with a fellowship in reproductive endocrinology and infertility at the University of Texas Southwestern Medical Center in Dallas.
Clinical Specialties
Obstetrics, Gynecology & Reproductive Sciences; Reproductive Endocrinology & Infertility
Fact Sheets
Surrogacy
Learn More on Yale MedicineIn Vitro Fertilization (IVF)
Learn More on Yale MedicinePolycystic Ovary Syndrome (PCOS)
Learn More on Yale MedicinePediatric Chemotherapy
Learn More on Yale Medicine
Board Certifications
Reproductive Endocrinology & Infertility
- Certification Organization
- AB of Obstetrics & Gynecology
- Latest Certification Date
- 2020
- Original Certification Date
- 1994
Obstetrics & Gynecology
- Certification Organization
- AB of Obstetrics & Gynecology
- Latest Certification Date
- 2020
- Original Certification Date
- 1988
Yale Medicine News
News
News
- October 14, 2024
Yale Ob/Gyn Participates in Fertility Preservation Conference
- October 14, 2024
Preserving Hope: Fertility Care for Patients with Cancer and Hematological Disorders
- June 14, 2019
Over 200 Yale Medicine Physicians Make 2019 ‘Best Doctors’ List
- April 15, 2009
Non-Invasive Management of Gynecologic Disorders
Get In Touch
Contacts
Email
Appointment Number
Clinic Fax Number
Mailing Address
Obstetrics, Gynecology & Reproductive Sciences
PO Box 208063
New Haven, CT 06520-8063
United States
Locations
Yale Obstetrics, Gynecology & Reproductive Services
Academic Office
Farnam Memorial Building
310 Cedar Street, Ste FMB 329K
New Haven, CT 06510
Patient Care Locations
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