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Groundbreaking Study Highlights Critical Gap in Global Mental Health Research

A landmark study led by the Latin American Genomics Consortium (LAGC), a pioneering collaborative network co-founded and co-led by Janitza Montalvo-Ortiz, PhD, assistant professor of psychiatry, reveals a significant disparity in psychiatric genomics research, with over 85% of participants in genome-wide association studies being of European ancestry.

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  • Gelernter, Polimanti New Editors-in-Chief of Complex Psychiatry

    Joel Gelernter, MD, Foundations Fund Professor of Psychiatry and Professor of Genetics and of Neuroscience; and Renato Polimanti, PhD, Assistant Professor of Psychiatry, will co-lead the journal Complex Psychiatry, which recently changed its name from Molecular Neuropsychiatry.

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  • Three Faculty Honored With VA Career Development Award

    Lynnette Averill, PhD, Assistant Professor of Psychiatry; Lorig Kachadourian, PhD, Assistant Professor of Psychiatry; and Janitza Montalvo-Ortiz, PhD, Assistant Professor of Psychiatry, were honored by the U.S. Department of Veterans Affairs with its Career Development Award.

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  • Yale Team Provides Link Between Cannabis and Aggressive Behavior

    In a new study, Yale researchers have pinpointed a specific gene responsible for regulating cannabis-induced aggression, with strong ramifications for the national discussion of cannabis legalization. Led by Janitza Montalvo-Ortiz, Assistant Professor of Psychiatry at the Yale School of Medicine, the research group implicated the serotonin 2B receptor gene (HTR2B) as the mediator between cannabis and aggressive behavior. Variance within the serotonin system, the brain’s emotional regulator, has previously been linked to impulsivity and violent behavior. The researchers scanned millions of nucleotides, the fundamental units of DNA, in a hypothesis-free genome-wide association study (GWAS) of cannabis-related physical aggression. They were surprised when this method specifically identified a result within the serotonin system. The finding, according to Montalvo-Ortiz, confirms the relationship between serotonin signaling and impulsivity.

    Source: Yale Scientific
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