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Welcome to the Montalvo-Ortiz Lab!

Montalvo-Ortiz Lab

Our group is focused on the understanding of genetic and epigenetic architecture of psychiatric disorders. We use cutting-edge approaches to dissect the genomic and epigenomic landscape of psychiatric disorders in human peripheral and postmortem brain tissue. We focused on the study of substance use disorders, trauma (child abuse and post-traumatic stress disorder), and major depression. Multi-omics datasets (genomics, methylomics, transcriptomics, proteomics) are investigated to understand better the underlying mechanisms and identify predictors or biomarkers for these disorders.

We also seek to advance psychiatric genomics in LatinX populations based on our work in the Latin American Genomics Consortium (LAGC) and Psychiatric Genomics Consortium (PGC). The LAGC is comprised by ~60 investigators representing several Latin American countries, including Mexico, Costa Rica, Colombia, Argentina, Chile, as well as the United States and Puerto Rico. The main goals include:

  1. Increasing sample size of genomic studies by meta-analysis
  2. Recruitment and genotyping of new samples
  3. Methods development
  4. Education and training

We are hiring!

Postdoc and postgrads positions are available. To apply, please email a cover letter, and up-to-date CV to janitza.montalvo-ortiz@yale.edu. Include the names and contact information for two references.

Our work is funded by the National Institute of Health and the Department of Veteran’s Affairs.