Selected Publications
2024
Shu S, Tsutsui Y, Nathawat R, Mi W. Dual function of LapB (YciM) in regulating Escherichia coli lipopolysaccharide synthesis. Proc Natl Acad Sci U S A 2024, 121: e2321510121. PMID: 38635633, DOI: 10.1073/pnas.2321510121.
2023
Krimmer SG, Bertoletti N, Suzuki Y, Katic L, Mohanty J, Shu S, Lee S, Lax I, Mi W, Schlessinger J. Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2300054120. doi: 10.1073/pnas.2300054120. Epub 2023 Mar 21. PubMed PMID: 36943885; PubMed Central PMCID: PMC10068818.
Shu S, Mi W. Separating Inner and Outer Membranes of Escherichia coli by EDTA-free Sucrose Gradient Centrifugation. Bio Protoc. 2023 Mar 20;13(6):e4638. doi: 10.21769/BioProtoc.4638. eCollection 2023 Mar 20. PubMed PMID: 36968434; PubMed Central PMCID: PMC10031520.
2022
Shu S, Mi W. Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli. Nat Commun. 2022 Aug 5;13(1):4576. doi: 10.1038/s41467-022-32277-1. PubMed PMID: 35931690; PubMed Central PMCID: PMC9356133.
2020
Wu X, Siggel M, Ovchinnikov S, Mi W, Svetlov V, Nudler E, Liao M, Hummer G, Rapoport TA. Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science. 2020 Apr 24;368(6489). doi: 10.1126/science.aaz2449. PubMed PMID: 32327568; PubMed Central PMCID: PMC7380553.
2019 and earlier
Ru H, Mi W, Zhang P, Alt FW, Schatz DG, Liao M, Wu H. DNA melting initiates the RAG catalytic pathway. Nat Struct Mol Biol. 2018 Aug;25(8):732-742. doi: 10.1038/s41594-018-0098-5. Epub 2018 Jul 30. PubMed PMID: 30061602; PubMed Central PMCID: PMC6080600.
Mi W, Li Y, Yoon SH, Ernst RK, Walz T, Liao M. Structural basis of MsbA-mediated lipopolysaccharide transport. Nature. 2017 Sep 14;549(7671):233-237. doi: 10.1038/nature23649. Epub 2017 Sep 6. PubMed PMID: 28869968; PubMed Central PMCID: PMC5759761.
Schoebel S*, Mi W*, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M. Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature. 2017 Aug 17;548(7667):352-355. doi: 10.1038/nature23314. Epub 2017 Jul 6. PubMed PMID: 28682307; PubMed Central PMCID: PMC5736104. * contribute equally.
Mi W, Li L, Su XD. 5,5'-Dithio-bis(2-nitrobenzoic acid) modification of cysteine improves the crystal quality of human chloride intracellular channel protein 2. Biochem Biophys Res Commun. 2008 Apr 18;368(4):919-22. doi: 10.1016/j.bbrc.2008.02.021. Epub 2008 Feb 14. PubMed PMID: 18280248.
Mi W, Liang YH, Li L, Su XD. The crystal structure of human chloride intracellular channel protein 2: a disulfide bond with functional implications. Proteins. 2008 Apr;71(1):509-13. doi: 10.1002/prot.21922. PubMed PMID: 18186468.