2024
Substance use patterns, quantities, and associated risk factors in women with polysubstance misuse
Fogelman N, Tate M, Wemm S, Sullivan L, Hart R, Vacey E, Fox H, Sinha R. Substance use patterns, quantities, and associated risk factors in women with polysubstance misuse. Addiction Biology 2024, 29: 10.1111/adb.13390. PMID: 38619491, PMCID: PMC11017971, DOI: 10.1111/adb.13390.Peer-Reviewed Original ResearchConceptsPolysubstance useDepressive symptomsSubstance use patternsDrug cravingRisk factorsPatterns of polysubstance useSingle substance useAssociated with polysubstance usePlacebo-controlled studyHigher cravingGuanfacine treatmentCross-sectional observational studyPolysubstance use patternsCraving managementLife eventsCravingPolysubstance misuseSubstance useOpioid amountsPain ratingsStress/traumaObservational studyAnxietyPainPolysubstance
2021
Alcohol craving and withdrawal at treatment entry prospectively predict alcohol use outcomes during outpatient treatment
Martins JS, Fogelman N, Wemm S, Hwang S, Sinha R. Alcohol craving and withdrawal at treatment entry prospectively predict alcohol use outcomes during outpatient treatment. Drug And Alcohol Dependence 2021, 231: 109253. PMID: 34998258, PMCID: PMC8818273, DOI: 10.1016/j.drugalcdep.2021.109253.Peer-Reviewed Original ResearchConceptsAlcohol use outcomesAlcohol cravingTreatment entryDays/weekSleep difficultiesOutpatient treatmentAbstinence symptomsUse outcomesPre-treatment alcohol useEffects of cravingTreatment-seeking adultsAlcohol useAlcohol use disorder treatmentRelapse prevention counselingDrinking-related outcomesHeavy drinkingDrinking days/weekOutpatient AUD treatmentGreater alcoholChronic alcohol useDistress symptomsUse disorder treatmentAUD treatmentAverage drinksCraving
2019
A day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment
Wemm SE, Larkin C, Hermes G, Tennen H, Sinha R. A day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment. Drug And Alcohol Dependence 2019, 204: 107569. PMID: 31574406, PMCID: PMC6916671, DOI: 10.1016/j.drugalcdep.2019.107569.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlcohol intakeEarly treatmentAlcohol use disorder treatmentStressful eventsNovel treatment approachesAlcohol relapse riskUse disorder treatmentNext dayWeeks of outpatientStress-induced cravingAlcohol use outcomesRelapse riskProspective analysisUse disordersAUD patientsTreatment approachesDisorder treatmentHigher cravingDaily diariesUse outcomesIntakeAUD individualsCravingDrinking amountWeaker Memory Performance Exacerbates Stress-Induced Cannabis Craving in Youths’ Daily Lives
Miranda R, Wemm SE, Padovano H, Carpenter RW, Emery NN, Gray JC, Mereish EH. Weaker Memory Performance Exacerbates Stress-Induced Cannabis Craving in Youths’ Daily Lives. Clinical Psychological Science 2019, 7: 1094-1108. PMID: 31737439, PMCID: PMC6857838, DOI: 10.1177/2167702619841976.Peer-Reviewed Original ResearchCue exposureWeaker memory performanceDrug cue responseEcological momentary assessmentMemory performanceAddiction positCue responsesStressful momentsHigher cravingMomentary assessmentMomentary stressSubstance misuseWMYouthControl capacityReal-world settingDrug useCravingCuesMemoryAdolescentsPositStimuliCannabisAssociation
2018
Stress responding and stress‐related changes in cue reactivity in heavy smokers, problem gamblers, and healthy controls
Wemm SE, Cao Z, Han L, Wulfert E. Stress responding and stress‐related changes in cue reactivity in heavy smokers, problem gamblers, and healthy controls. Addiction Biology 2018, 25: e12687. PMID: 30421575, PMCID: PMC6513727, DOI: 10.1111/adb.12687.Peer-Reviewed Original ResearchConceptsHealthy controlsBlunted cortisol responseMaladaptive stress responsesHigher subjective stressCue-related cravingHeavy smokersStress-related changesControl group responsesSmokersCortisol responseCortisol levelsSubjective stress responsesPsychosocial stressorsSalivary cortisolAcute stressorCue reactivityBehavioral addictionsCravingSubjective cravingSmokingSubstance addictionSubjective responsesCortisolStress responseSubjective stressAppetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment
Mereish EH, Padovano HT, Wemm S, Miranda R. Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment. Psychopharmacology 2018, 235: 1933-1943. PMID: 29623354, PMCID: PMC6015780, DOI: 10.1007/s00213-018-4890-z.Peer-Reviewed Original ResearchConceptsCue-elicited cravingStartle reactivityEcological momentary assessment protocolHuman laboratoryCannabis-related stimuliCannabis-related cuesFrequent cannabis usersCross-level interactionsCannabis cuesResultsMultilevel modelsDrug cuesMotivational processesResponse patternsMotivational systemsPicture cuesPleasant stimuliStartle modulationCannabis usersCannabis useCuesStartle magnitudeCravingReal-world environmentsAge 16Startle reflex