Publications
- The temporal effects of topical NF-κB inhibition, in the in vivo prevention of bile-related oncogenic mRNA and miRNA phenotypes in murine hypopharyngeal mucosa: a preclinical model.Vageli DP, Kasle D, Doukas SG, Doukas PG, Sasaki CT. Oncotarget. 2020 Sep 1; 2020 Sep 1. PMID: 32934775.
- The in vivo preventive and therapeutic properties of curcumin in bile reflux-related oncogenesis of the hypopharynx.Doukas SG, Doukas PG, Sasaki CT, Vageli D. J Cell Mol Med. 2020 Sep; 2020 Jul 21. PMID: 32691972.
- The role of bile reflux and its related NF-κB activated pathway in progression of hypopharyngeal squamous cell cancer.Sasaki CT, Hajek M, Doukas SG, Vageli DP. Oral Oncol. 2020 Jun; 2020 Apr 2. PMID: 32247988.
- The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights.Sasaki CT, Doukas SG, Costa J, Vageli DP. Cancers (Basel). 2020 Apr 25; 2020 Apr 25. PMID: 32344873.
- The Effect of NNK, A Tobacco Smoke Carcinogen, on the miRNA and Mismatch DNA Repair Expression Profiles in Lung and Head and Neck Squamous Cancer Cells.Doukas SG, Vageli DP, Lazopoulos G, Spandidos DA, Sasaki CT, Tsatsakis A. Cells. 2020 Apr 21; 2020 Apr 21. PMID: 32326378.
- Biliary reflux as a causal factor in hypopharyngeal carcinoma: New clinical evidence and implications.Sasaki CT, Doukas SG, Costa J, Vageli DP. Cancer. 2019 Oct 15; 2019 Jul 16. PMID: 31310330.
- Hypopharyngeal Diverticulum: Toward a Unified Understanding of Its Etiopathogenesis.Kasle DA, Torabi SJ, Boey H, Sasaki CT. Dysphagia. 2019 Oct; 2019 Jun 22. PMID: 31230142.
- Biliary tumorigenic effect on hypopharyngeal cells is significantly enhanced by pH reduction.Doukas SG, Cardoso B, Tower JI, Vageli DP, Sasaki CT. Cancer Med. 2019 Aug; 2019 Jun 7. PMID: 31173474.
- Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells.Doukas PG, Vageli DP, Doukas SG, Sasaki CT. Oncotarget. 2019 May 21; 2019 May 21. PMID: 31164956.
- Curcumin prevents the bile reflux-induced NF-κB-related mRNA oncogenic phenotype, in human hypopharyngeal cells.Vageli DP, Doukas SG, Spock T, Sasaki CT. J Cell Mol Med. 2018 Sep; 2018 Jun 17. PMID: 29911313.
- In search of a longitudinal animal model of evoked swallow function.Langerman J, Doukas SG, Hasegawa H, Goodrich J, Lerner M, Sasaki C. Laryngoscope Investig Otolaryngol. 2018 Jun; 2018 May 14. PMID: 30062134.
- NF-κB inhibition reverses acidic bile-induced miR-21, miR-155, miR-192, miR-34a, miR-375 and miR-451a deregulations in human hypopharyngeal cells.Doukas SG, Vageli DP, Sasaki CT. J Cell Mol Med. 2018 May; 2018 Mar 8. PMID: 29516639.
- In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile-Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa.Sasaki CT, Doukas SG, Vageli DP. Neoplasia. 2018 Apr; 2018 Mar 9. PMID: 29529473.
- Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells.Vageli DP, Doukas SG, Sasaki CT. Oncotarget. 2018 Jan 19; 2017 Dec 12. PMID: 29464041.
- HPV-Positive Oropharyngeal Cancer Via p16 Immunohistochemistry in Japan.Toman J, Von Larson S, Umeno H, Kurita T, Furusaka T, Hasegawa H, Prasad ML, Sasaki CT. Ann Otol Rhinol Laryngol. 2017 Feb. PMID: 27913709.
- The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells.Sasaki CT, Toman J, Vageli D. PLoS One. 2016; 2016 Dec 14. PMID: 27973541.
- miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo.Sasaki CT, Vageli DP. Neoplasia. 2016 Jun; 2016 May 25. PMID: 27292022.
- In vitro model for gastroduodenal reflux-induced nuclear factor-kappaB activation and its role in hypopharyngeal carcinogenesis.Sasaki CT, Issaeva N, Vageli DP. Head Neck. 2016 Apr; 2015 Nov 11. PMID: 26559497.
- Gastro-duodenal fluid induced nuclear factor-κappaB activation and early pre-malignant alterations in murine hypopharyngeal mucosa.Vageli DP, Prasad ML, Sasaki CT. Oncotarget. 2016 Feb 2. PMID: 26745676.
- Evaluation of PD-L1 Expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma.Vassilakopoulou M, Avgeris M, Velcheti V, Kotoula V, Rampias T, Chatzopoulos K, Perisanidis C, Kontos CK, Giotakis AI, Scorilas A, Rimm D, Sasaki C, Fountzilas G, Psyrri A. Clin Cancer Res. 2016 Feb 1; 2015 Sep 25. PMID: 26408403.
- Is the External Branch of the Superior Laryngeal Nerve Dispensable in Thyroid Surgery?Folk D, Wahba B, Sasaki CT. Thyroid. 2016 Jan; 2015 Nov 23. PMID: 26528734.
- Thyroarytenoid cross-innervation by the external branch of the superior laryngeal nerve in the porcine model.Paskhover B, Wadie M, Sasaki CT. Laryngoscope. 2015 Jan; 2014 Aug 14. PMID: 25131261.
- The pharyngeal plexus-mediated glottic closure response and associated neural connections of the plexus.Paskhover B, Wadie M, Sasaki CT. JAMA Otolaryngol Head Neck Surg. 2014 Nov. PMID: 25321610.
- Hajek revisited: a histological examination of the quadrangular membrane.Young N, Abdelmessih MW, Sasaki C. Ann Otol Rhinol Laryngol. 2014 Nov; 2014 Jun 19. PMID: 24947408.
- RAS/PI3K crosstalk and cetuximab resistance in head and neck squamous cell carcinoma.Rampias T, Giagini A, Siolos S, Matsuzaki H, Sasaki C, Scorilas A, Psyrri A. Clin Cancer Res. 2014 Jun 1; 2014 Apr 2. PMID: 24696319.
- Molecular mechanisms of HPV induced carcinogenesis in head and neck.Rampias T, Sasaki C, Psyrri A. Oral Oncol. 2014 May; 2013 Aug 13. PMID: 23953776.
- Markers of epithelial to mesenchymal transition in association with survival in head and neck squamous cell carcinoma (HNSCC).Pectasides E, Rampias T, Sasaki C, Perisanidis C, Kouloulias V, Burtness B, Zaramboukas T, Rimm D, Fountzilas G, Psyrri A. PLoS One. 2014; 2014 Apr 10. PMID: 24722213.
- Contribution of the pharyngeal plexus to vocal cord adduction.Matsuzaki H, Paskhover B, Sasaki CT. Laryngoscope. 2014 Feb; 2013 Sep 19. PMID: 23929757.
- Molecular profile of head and neck squamous cell carcinomas bearing p16 high phenotype.Rampias T, Pectasides E, Prasad M, Sasaki C, Gouveris P, Dimou A, Kountourakis P, Perisanidis C, Burtness B, Zaramboukas T, Rimm D, Fountzilas G, Psyrri A. Ann Oncol. 2013 Aug; 2013 Feb 13. PMID: 23406730.
- Multidrug resistance in mucoepidermoid carcinoma of the parotid gland--immunohistochemical investigations of P-glycoprotein expression.Furusaka T, Sasaki CT, Matsuda A, Susaki Y, Matsuda H, Ikeda M. Acta Otolaryngol. 2013 May; 2013 Jan 28. PMID: 23350593.
- Future directions in research, treatment and prevention of HPV-related squamous cell carcinoma of the head and neck.Psyrri A, Sasaki C, Vassilakopoulou M, Dimitriadis G, Rampias T. Head Neck Pathol. 2012 Jul; 2012 Jul 3. PMID: 22782231.
- Neuromuscular basis for ventricular fold function.Young N, Wadie M, Sasaki CT. Ann Otol Rhinol Laryngol. 2012 May. PMID: 22724277.
- Comparative prognostic value of epidermal growth factor quantitative protein expression compared with FISH for head and neck squamous cell carcinoma.Pectasides E, Rampias T, Kountourakis P, Sasaki C, Kowalski D, Fountzilas G, Zaramboukas T, Rimm D, Burtness B, Psyrri A. Clin Cancer Res. 2011 May 1; 2011 Feb 25. PMID: 21355076.
Other Publications
Sasaki CT: 2nd Edition: Laryngeal Physiology for the Surgeon and Clinician, San Diego, CA, Plural Publishing, Inc, 2015.
Sasaki CT: Chapter: “Laryngeal Disorders” The Merck Manual, 18th and 19th Editions, West Point, PA, Merck and Co., Inc., 2006, 2014.
Larson S, Deshpande H, Sasaki CT: Laryngeal Cancer, Brit. Med. J., (accepted 2014).
Lerner M, Sasaki CT: “Physiology and Phylogeny of the Larynx and Trachea,” in Laryngeal and Tracheobronchial Stenosis, Plural Publ., San Diego, CA, 2013.
Sasaki CT, Young N, Matsuzaki H, Paskhover B: “Development, Anatomy and Physiology of the Larynx” in Ballenger’s Otorhinolaryngology Head and Neck Surgery 18th Ed., People’s Medical Publ., 2013.
Wadie M, Adam S, Sasaki CT: “Development, Anatomy and Physiology of the Larynx” in Shaker et al, Principles of Deglutition, Springer Science and Business Media, New York, NY, 2013.
Young N, Matsuzaki H, Sasaki CT: “Physiology of the Larynx” in Fried M, Tan. Geller M: Clinical Laryngology Thieme Publ, New York, NY, 2013.
Sasaki CT, Young N, Matsuzaki H, Paskhover B: “Anatomy of the Human Larynx” in Diagnosis and Treatment of Voice Disorders, 4th Ed., San Diego, CA, Plural Publ., 2013.
Deshpande H, Sasaki CT: Laryngeal Cancer, Best Practice/Point of Care Update 2012, British Medical Journal, 2012.