Publications
Selected Publications
- Emilia Krypotou 1 2, Guy E Townsend 1 2 3, Xiaohui Gao 1, Shoichi Tachiyama 1 2, Jun Liu 1 2, Nick D Pokorzynski 1, Andrew L Goodman 1 2, Eduardo A Groisman 1 2. Bacteria require phase separation for fitness in the mammalian gut. Science, 2023.
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Kurni Kurniyati, Yunjie Chang, Wangbiao Guo, Jun Liu, Michael G. Malkowski, Chunhao Li. Anti-σ28 Factor FlgM Regulates Flagellin Gene Expression and Flagellar Polarity of Treponema denticola. J Bact, 2023.
- Jason Gorman, Chunyan Wang…Jun Liu, Mario Roederer, Peter D Kwong, et al. Cryo-EM structures of prefusion SIV envelope trimer. Nat Struct Mol Biol, 2022.
- Donghyun Park, Samuel Steiner, Meng Shao, Craig R. Roy, Jun Liu. Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System, Infect Immun, 2022.
- Shuaiqi Guo1,2 and Jun Liu1,2*: The Bacterial Flagellar Motor: Insig hts Into Torque Generation, Rotational Switching, and Mechanosensing, Front Microbiol, 2022.
- Shoichi Tachiyama, Kar L. Chan, Xiaolin Liu, Skander Hathroubi, Wenwei Li, Briana Peterson, Mohammad F. Khan, Karen M. Ottemann, Jun Liu , and Anna Roujeinikova: The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation, PNAS, 2022.
- Shuaiqi Guo, Hui Xu, Yunjie Chang, Md A. Motaleb, and Jun Liu: FliL ring enhances the function of periplasmic flagella, PNAS, 2022. Also highlighted in: How Bacteria Swim: Yale Researchers Discover New Mechanisms
- Yunije Chang, Brittany L. Carroll & Jun Liu: Structural basis of bacterial flagellar motor rotation and switching, Trends in Microbiology, 2021.
- Donghyun Park, David Chetrit, Bo Hu, Craig R Roy, Jun Liu: Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding, mBio, 2020.
- Brittany L. Carroll and Jun Liu: Structural conservation and adaptation of the bacterial flagellar motor, Biomolecules, 2020.
- Yunjie Chang, Kai Zhang, Brittany L. Carroll, Xiaowei Zhao, Nyles W. Charon, Steven J. Norris, Md A. Motaleb, Chunhao Li & Jun Liu: Molecular mechanism for rotational switching of the bacterial flagellar motor, Nat Struct Mol Biol, 2020.
- Ze Li, Wenwei Li, Maolin Lu, Julian Bess Jr, Cara W. Chao, Jason Gorman, Daniel S. Terry, Baoshan Zhang, Tongqing Zhou, Scott C. Blanchard, Peter D. Kwong, Jeffrey D . Lifson, Walther Mothes & Jun Liu: Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles, Nat Struct Mol Biol, 2020.
- Chang Y, Moon KH, Zhao X, Norris SJ, Motaleb MA, Liu J. Structural insights into flagellar stator-rotor interactions, Elife, 2019.
- Wang C, Tu J, Liu J, Molineux IJ. Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography, Nat Microbiol, 2019.
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Park D, Lara-Tejero M, Waxham MN, Li W, Hu B, Galán JE, Liu J. Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography, Elife, 2018.
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Zhu S, Nishikino T, Hu B, Kojima S, Homma M, Liu J: Molecular architecture of the sheathed polar flagellum in Vibrio alginolyticus, Proc Natl Acad Sci U S A, 2017.
- Hu B, Lara-Tejero M, Kong Q, Galán JE, Liu J: In situ molecular architecture of the Salmonella type III secretion machine, Cell, 2017.
- Hu B, Margolin W, Molineux IJ, Liu J, Structural remodeling of bacteriophage T4 and host membranes during infection initiation, Proc Natl Acad Sci U S A, 2015.
- Hu B, Morado DR, Margolin W, Rohde JR, Arizmendi O, Picking WL, Picking WD, Liu J: Visualization of the type III secretion sorting platform of Shigella flexneri. Proc Natl Acad Sci U S A, 2015.
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Zhao X, Zhang K, Boquoi T, Hu B, Motaleb MA, Miller K, James M, Charon NW, Manson MD, Norris SJ, Li C, Liu J: Cryo-Electron Tomography Reveals the Sequential Assembly of Bacterial Flagella in Borrelia burgdorferi, Proc Natl Acad Sci U S A, 2013.
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Hu B, Margolin W, Molineux IJ, Liu J: The Bacteriophage T7 Virion Undergoes Extensive Structural Remodeling during infection, Science, 2013.
- Liu J, Hu B, Morado DR, Jani S, Manson MD, Margolin W: Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells, Proc Natl Acad Sci U S A, 2012.
- Luther PK, Winkler H, Taylor K, Zoghbi ME, Craig R, Padrón R, Squire JM, Liu J: Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle, Proc Natl Acad Sci U S A, 2011.
- Liu J, Lin T, Botkin DJ, McCrum E, Winkler H, Norris SJ: Intact Flagellar Motor of Borrelia burgdorferi Revealed by Cryo-Electron Tomography: Evidence for Stator Ring Curvature and Rotor/C Ring Assembly Flexion, J Bacteriol, 2009.