All Publications

• Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity.Han W, Peng BZ, Wang C, Townsend GE 2nd, Barry NA, Peske F, Goodman AL, Liu J, Rodnina MV, Groisman EA. EMBO J. 2023 Jan 16; 2022 Dec 6. PMID: 36472247.
• An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria.Gupta KR, Gwin CM, Rahlwes KC, Biegas KJ, Wang C, Park JH, Liu J, Swarts BM, Morita YS, Rego EH. Elife. 2022 Nov 8; 2022 Nov 8. PMID: 36346214.
• Cryo-EM structures of prefusion SIV envelope trimer.Gorman J, Wang C, Mason RD, Nazzari AF, Welles HC, Zhou T, Bess JW Jr, Bylund T, Lee M, Tsybovsky Y, Verardi R, Wang S, Yang Y, Zhang B, Rawi R, Keele BF, Lifson JD, Liu J, Roederer M, Kwong PD. Nat Struct Mol Biol. 2022 Nov; 2022 Nov 7. PMID: 36344847.
• Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System.Park D, Steiner S, Shao M, Roy CR, Liu J. Infect Immun. 2022 Oct 20; 2022 Oct 3. PMID: 36190257.
• A Tripartite Efflux System Affects Flagellum Stability in Helicobacter pylori.Gibson K, Chu JK, Zhu S, Nguyen D, Mrázek J, Liu J, Hoover TR. Int J Mol Sci. 2022 Oct 1; 2022 Oct 1. PMID: 36232924.
• Editorial: Biological rotary nanomotors.Manson MD, Nan B, Lele PP, Liu J, Duncan TM. Front Microbiol. 2022; 2022 Sep 21. PMID: 36212881.
• Identification and Characterization of the Alternative σ(28) Factor in Treponema denticola.Kurniyati K, Chang Y, Liu J, Li C. J Bacteriol. 2022 Sep 20; 2022 Aug 31. PMID: 36043861.
• Transcriptome of Epibiont Saccharibacteria Nanosynbacter lyticus Strain TM7x During the Establishment of Symbiosis.Hendrickson EL, Bor B, Kerns KA, Lamont EI, Chang Y, Liu J, Cen L, Schulte F, Hardt M, Shi W, He X, McLean JS. J Bacteriol. 2022 Sep 20; 2022 Aug 17. PMID: 35975994.
• Transcriptional and functional characterizations of multiple flagellin genes in spirochetes.Kurniyati K, Chang Y, Liu J, Li C. Mol Microbiol. 2022 Sep; 2022 Jul 18. PMID: 35776658.
• The Bacterial Flagellar Motor: Insights Into Torque Generation, Rotational Switching, and Mechanosensing.Guo S, Liu J. Front Microbiol. 2022; 2022 May 30. PMID: 35711788.
• Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.Wang F, Cvirkaite-Krupovic V, Vos M, Beltran LC, Kreutzberger MAB, Winter JM, Su Z, Liu J, Schouten S, Krupovic M, Egelman EH. Cell. 2022 Apr 14; 2022 Mar 23. PMID: 35325592.
• FliL ring enhances the function of periplasmic flagella.Guo S, Xu H, Chang Y, Motaleb MA, Liu J. Proc Natl Acad Sci U S A. 2022 Mar 15; 2022 Mar 7. PMID: 35254893.
• The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation.Tachiyama S, Chan KL, Liu X, Hathroubi S, Peterson B, Khan MF, Ottemann KM, Liu J, Roujeinikova A. Proc Natl Acad Sci U S A. 2022 Jan 25. PMID: 35046042.
• Characterization of the Flagellar Collar Reveals Structural Plasticity Essential for Spirochete Motility.Chang Y, Xu H, Motaleb MA, Liu J. mBio. 2021 Dec 21; 2021 Nov 23. PMID: 34809456.
• Role of the major determinant of polar flagellation FlhG in the endoflagella-containing spirochete Leptospira.Fule L, Halifa R, Fontana C, Sismeiro O, Legendre R, Varet H, Coppée JY, Murray GL, Adler B, Hendrixson DR, Buschiazzo A, Guo S, Liu J, Picardeau M. Mol Microbiol. 2021 Nov; 2021 Oct 30. PMID: 34657338.
• Structural basis of bacterial flagellar motor rotation and switching.Chang Y, Carroll BL, Liu J. Trends Microbiol. 2021 Nov; 2021 Apr 14. PMID: 33865677.
• BB0259 Encompasses a Peptidoglycan Lytic Enzyme Function for Proper Assembly of Periplasmic Flagella in Borrelia burgdorferi.Xu H, Hu B, Flesher DA, Liu J, Motaleb MA. Front Microbiol. 2021; 2021 Oct 1. PMID: 34659138.
• Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli.Xiang Y, Surovtsev IV, Chang Y, Govers SK, Parry BR, Liu J, Jacobs-Wagner C. Cell. 2021 Jul 8; 2021 Jun 28. PMID: 34186018.
• Composition and Biophysical Properties of the Sorting Platform Pods in the Shigella Type III Secretion System.Tachiyama S, Skaar R, Chang Y, Carroll BL, Muthuramalingam M, Whittier SK, Barta ML, Picking WL, Liu J, Picking WD. Front Cell Infect Microbiol. 2021; 2021 Jun 3. PMID: 34150677.
• The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete.Davis MM, Brock AM, DeHart TG, Boribong BP, Lee K, McClune ME, Chang Y, Cramer N, Liu J, Jones CN, Jutras BL. PLoS Pathog. 2021 May; 2021 May 13. PMID: 33984073.
• Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals.Radhakrishnan A, Li X, Grushin K, Krishnakumar SS, Liu J, Rothman JE. Proc Natl Acad Sci U S A. 2021 Feb 2. PMID: 33468631.
• A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi.Takacs CN, Scott M, Chang Y, Kloos ZA, Irnov I, Rosa PA, Liu J, Jacobs-Wagner C. Appl Environ Microbiol. 2020 Nov 30; 2020 Nov 30. PMID: 33257311.
• Molecular mechanism for rotational switching of the bacterial flagellar motor.Chang Y, Zhang K, Carroll BL, Zhao X, Charon NW, Norris SJ, Motaleb MA, Li C, Liu J. Nat Struct Mol Biol. 2020 Nov; 2020 Sep 7. PMID: 32895555.
• Structural Conservation and Adaptation of the Bacterial Flagella Motor.Carroll BL, Liu J. Biomolecules. 2020 Oct 29; 2020 Oct 29. PMID: 33138111.
• The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching.Carroll BL, Nishikino T, Guo W, Zhu S, Kojima S, Homma M, Liu J. Elife. 2020 Sep 7; 2020 Sep 7. PMID: 32893817.
• Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles.Li Z, Li W, Lu M, Bess J Jr, Chao CW, Gorman J, Terry DS, Zhang B, Zhou T, Blanchard SC, Kwong PD, Lifson JD, Mothes W, Liu J. Nat Struct Mol Biol. 2020 Aug; 2020 Jun 29. PMID: 32601441.
• Seeing a Contractile Bactericidal Nanomachine in Action at Near-Atomic Resolution.Gong Q, Liu J. Biochemistry. 2020 Jun 23; 2020 Jun 9. PMID: 32517471.
• Establishing rod shape from spherical, peptidoglycan-deficient bacterial spores.Zhang H, Mulholland GA, Seef S, Zhu S, Liu J, Mignot T, Nan B. Proc Natl Acad Sci U S A. 2020 Jun 23; 2020 Jun 8. PMID: 32513721.
• FlhF regulates the number and configuration of periplasmic flagella in Borrelia burgdorferi.Zhang K, He J, Cantalano C, Guo Y, Liu J, Li C. Mol Microbiol. 2020 Jun; 2020 Feb 21. PMID: 32039533.
• Applying Live Cell Imaging and Cryo-Electron Tomography to Resolve Spatiotemporal Features of the Legionella pneumophila Dot/Icm Secretion System.Chetrit D, Park D, Hu B, Liu J, Roy CR. J Vis Exp. 2020 Mar 10; 2020 Mar 10. PMID: 32225141.
• Phylogenetic Distribution, Ultrastructure, and Function of Bacterial Flagellar Sheaths.Chu J, Liu J, Hoover TR. Biomolecules. 2020 Feb 27; 2020 Feb 27. PMID: 32120823.
• Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding.Park D, Chetrit D, Hu B, Roy CR, Liu J. mBio. 2020 Feb 18; 2020 Feb 18. PMID: 32071271.
• BB0326 is responsible for the formation of periplasmic flagellar collar and assembly of the stator complex in Borrelia burgdorferi.Xu H, He J, Liu J, Motaleb MA. Mol Microbiol. 2020 Feb; 2019 Dec 8. PMID: 31743518.
• In Situ Structure of the Vibrio Polar Flagellum Reveals a Distinct Outer Membrane Complex and Its Specific Interaction with the Stator.Zhu S, Nishikino T, Takekawa N, Terashima H, Kojima S, Imada K, Homma M, Liu J. J Bacteriol. 2020 Jan 29; 2020 Jan 29. PMID: 31767780.
• The cytoplasmic domain of MxiG interacts with MxiK and directs assembly of the sorting platform in the Shigella type III secretion system.Tachiyama S, Chang Y, Muthuramalingam M, Hu B, Barta ML, Picking WL, Liu J, Picking WD. J Biol Chem. 2019 Dec 13; 2019 Nov 7. PMID: 31699894.
• High-resolution view of the type III secretion export apparatus in situ reveals membrane remodeling and a secretion pathway.Butan C, Lara-Tejero M, Li W, Liu J, Galán JE. Proc Natl Acad Sci U S A. 2019 Dec 3; 2019 Nov 19. PMID: 31744874.
• Loss of a Cardiolipin Synthase in Helicobacter pylori G27 Blocks Flagellum Assembly.Chu JK, Zhu S, Herrera CM, Henderson JC, Liu J, Trent MS, Hoover TR. J Bacteriol. 2019 Nov 1; 2019 Oct 4. PMID: 31427391.
• Structural insights into flagellar stator-rotor interactions.Chang Y, Moon KH, Zhao X, Norris SJ, Motaleb MA, Liu J. Elife. 2019 Jul 17; 2019 Jul 17. PMID: 31313986.
• Architecture and Assembly of Periplasmic Flagellum.Chang Y, Liu J. Microbiol Spectr. 2019 Jul. PMID: 31373267.
• In Situ Structures of Polar and Lateral Flagella Revealed by Cryo-Electron Tomography.Zhu S, Schniederberend M, Zhitnitsky D, Jain R, Galán JE, Kazmierczak BI, Liu J. J Bacteriol. 2019 Jul 1; 2019 Jun 10. PMID: 31010901.
• Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography.Wang C, Tu J, Liu J, Molineux IJ. Nat Microbiol. 2019 Jun; 2019 Mar 18. PMID: 30886360.
• Analysis of a flagellar filament cap mutant reveals that HtrA serine protease degrades unfolded flagellin protein in the periplasm of Borrelia burgdorferi.Zhang K, Qin Z, Chang Y, Liu J, Malkowski MG, Shipa S, Li L, Qiu W, Zhang JR, Li C. Mol Microbiol. 2019 Jun; 2019 Apr 26. PMID: 30883947.
• A pleiotropic role of FlaG in regulating the cell morphogenesis and flagellar homeostasis at the cell poles of Treponema denticola.Kurniyati K, Liu J, Zhang JR, Min Y, Li C. Cell Microbiol. 2019 Feb; 2018 Jul 23. PMID: 29935042.
• Cryo-electron tomography of periplasmic flagella in Borrelia burgdorferi reveals a distinct cytoplasmic ATPase complex.Qin Z, Tu J, Lin T, Norris SJ, Li C, Motaleb MA, Liu J. PLoS Biol. 2018 Nov; 2018 Nov 9. PMID: 30412577.
• A tetratricopeptide repeat domain protein has profound effects on assembly of periplasmic flagella, morphology and motility of the lyme disease spirochete Borrelia burgdorferi.Moon KH, Zhao X, Xu H, Liu J, Motaleb MA. Mol Microbiol. 2018 Nov; 2018 Oct 15. PMID: 30303576.
• The Vibrio H-Ring Facilitates the Outer Membrane Penetration of the Polar Sheathed Flagellum.Zhu S, Nishikino T, Kojima S, Homma M, Liu J. J Bacteriol. 2018 Nov 1; 2018 Oct 10. PMID: 30104237.
• Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography.Park D, Lara-Tejero M, Waxham MN, Li W, Hu B, Galán JE, Liu J. Elife. 2018 Oct 3; 2018 Oct 3. PMID: 30281019.
• A unique cytoplasmic ATPase complex defines the Legionella pneumophila type IV secretion channel.Chetrit D, Hu B, Christie PJ, Roy CR, Liu J. Nat Microbiol. 2018 Jun; 2018 May 21. PMID: 29784975.
• Visualizing Chemoreceptor Arrays in Bacterial Minicells by Cryo-Electron Tomography and Subtomogram Analysis.Qin Z, Hu B, Liu J. Methods Mol Biol. 2018. PMID: 29429093.
• Molecular architecture of the sheathed polar flagellum in Vibrio alginolyticus.Zhu S, Nishikino T, Hu B, Kojima S, Homma M, Liu J. Proc Natl Acad Sci U S A. 2017 Oct 10; 2017 Sep 25. PMID: 28973904.