2024
Identifying Factors Linked to Current Patterns of Alcohol Consumption in U.S. Veterans with a History of Alcohol Use Disorder
Jalilian-Khave L, Stefanovics E, Potenza M, Pietrzak R. Identifying Factors Linked to Current Patterns of Alcohol Consumption in U.S. Veterans with a History of Alcohol Use Disorder. International Journal Of Mental Health And Addiction 2024, 1-18. DOI: 10.1007/s11469-024-01412-y.Peer-Reviewed Original ResearchHistory of alcohol use disorderAlcohol use disorderUse disorderU.S. veteransHazardous drinkingNational Health and ResilienceLifetime history of alcohol use disorderLifetime alcohol use disorderAlcohol use problemsDrug use disordersPatterns of alcohol consumptionAlcohol use patternsHigher education levelNationally representative sampleMultinomial logistic regression analysisVeterans StudyLifetime historyLifetime traumaAlcohol consumption patternsQuality of lifeNon-veteransLogistic regression analysisPsychosocial traitsTreatment effortsPsychosocial factorsReply to Pomara et al: A potential role for sTREM2 in PTSD?
Bonomi R, Pietrzak R, Cosgrove K. Reply to Pomara et al: A potential role for sTREM2 in PTSD? Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2418104121. PMID: 39536072, DOI: 10.1073/pnas.2418104121.Peer-Reviewed Original ResearchUnveiling the Structure in Mental Disorder Presentations
Spiller T, Duek O, Helmer M, Murray J, Fielstein E, Pietrzak R, von Känel R, Harpaz-Rotem I. Unveiling the Structure in Mental Disorder Presentations. JAMA Psychiatry 2024, 81: 1101-1107. PMID: 39110437, PMCID: PMC11307158, DOI: 10.1001/jamapsychiatry.2024.2047.Peer-Reviewed Original ResearchSymptom combinationsNational Institute of Mental Health Data ArchivePosttraumatic stress disorderDiagnostic criteriaHeterogeneity of symptomsSecondary data analysisCross-sectional studyRevision of diagnostic criteriaSymptom-based definitionsDSM criteriaStress disorderSymptom heterogeneityDisorder presentationsClinical populationsMain OutcomesAssess symptomsGroup of individualsParticipantsSymptomsNational InstituteDisordersIndividualsSchizophreniaAnxietyIndividual frequenciesTrauma-Related Nightmares Among U.S. Veterans: Findings from a Nationally Representative Study
Worley C, Meshberg-Cohen S, Fischer I, Pietrzak R. Trauma-Related Nightmares Among U.S. Veterans: Findings from a Nationally Representative Study. Sleep Medicine 2024 DOI: 10.1016/j.sleep.2024.11.031.Peer-Reviewed Original ResearchTrauma-related nightmaresNationally representative sampleSuicidal ideationTreatment of trauma-related nightmaresRepresentative sampleAssociated with adverse mental healthExposure to adverse childhood eventsTrauma-exposed veteransAssociated with elevated oddsAdverse mental healthIncreased suicide riskNationally representative studyAdverse childhood eventsUS military veteransTransdiagnostic assessmentNightmare severityTrauma exposureHealth historySociodemographic factorsMental healthSuicide riskTrauma typesPsychiatric conditionsSociodemographic characteristicsPsychosocial functioningPosttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans
Fischer I, Na P, Nagamatsu S, Jeste D, Cabrera-Mendoza B, Montalvo-Ortiz J, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans. JAMA Psychiatry 2024, 81 PMID: 39476130, PMCID: PMC11581715, DOI: 10.1001/jamapsychiatry.2024.3403.Peer-Reviewed Original ResearchPrevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans.
Fischer I, Na P, Harpaz-Rotem I, Marx B, Pietrzak R. Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans. The Journal Of Clinical Psychiatry 2024, 85 PMID: 39480145, DOI: 10.4088/jcp.24m15465.Peer-Reviewed Original ResearchConceptsSubthreshold posttraumatic stress disorderPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersLifetime psychiatric disordersUS veteransUS military veteransSymptom-related distressStress disorderPsychiatric disordersSymptom clustersTreating veteransCriterion AMilitary veteransTraumatic eventsCognitive functionWorking case definitionMental healthCriterion FFunctional impairmentVeteransNationally representative sampleFunctional correlatesDisordersElevated oddsGreater oddsPsychological Resilience of Mental Health Workers During the Russia-Ukraine War: Implications for Clinical Interventions.
Kang H, Fischer I, Vus V, Kolyshkina A, Ponomarenko L, Chobanian A, Esterlis I, Pietrzak R. Psychological Resilience of Mental Health Workers During the Russia-Ukraine War: Implications for Clinical Interventions. The Primary Care Companion For CNS Disorders 2024, 26 PMID: 39441963, DOI: 10.4088/pcc.24m03761.Peer-Reviewed Original ResearchConceptsMental health workersPsychological resilienceHealth workersDistress scoresClinical interventionsMental health symptomsGreater resilienceAssociated with greater resilienceWar-related exposuresWork-related stressorsConvenience samplePsychosocial characteristicsHealth symptomsMeaning in lifeOccupational stressorsPresence of meaning in lifeOccupational stressSocial connectednessPromote resiliencePsychiatric resilienceGreater levelsInterventionScoresSocial relationshipsAuthor affiliationGenes in context: path to more precise risk prediction in psychiatry?
Na P, Pietrzak R, Gelernter J. Genes in context: path to more precise risk prediction in psychiatry? The British Journal Of Psychiatry 2024, 1-2. PMID: 39422146, DOI: 10.1192/bjp.2024.151.Peer-Reviewed Original ResearchLoneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors
Ong A, Cintron D, Rottenberg J, Panaite V, Fischer I, Na P, Jeste D, Pietrzak R. Loneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors. The Journals Of Gerontology Series B 2024, gbae171. PMID: 39390809, DOI: 10.1093/geronb/gbae171.Peer-Reviewed Original ResearchGrowth mixture modelingU.S. military veteransLoneliness trajectoriesMilitary veteransLongitudinal Study of RiskNational Health and ResilienceEarly life adversitySelf-report ratingsProtective factorsWorse cognitive functionMental health concernsPhysical health outcomesHealth concernAdverse childhood experiencesRisk factorsLongitudinal cohort studyStudy of riskNationally representative samplePotential psychosocial riskPromote social connectednessSignificant public health concernVeterans StudyLife adversityThree-step regression analysisCognitive functionLongitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the AURORA study
Hyatt C, Reddi P, Sharpe B, Michopoulos V, van Rooij S, House S, Beaudoin F, An X, Stevens J, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Pascual J, Seamon M, Harris E, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, McLean S, Kessler R, Ressler K, Koenen K, Maples-Keller J. Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the AURORA study. Journal Of Research In Personality 2024, 112: 104524. DOI: 10.1016/j.jrp.2024.104524.Peer-Reviewed Original ResearchImpulsive personality traitsPTSD symptomsPersonality traitsOne-year post-traumaSevere PTSD symptomsPost-traumaFactor modelNegative urgencyLow agreeablenessLow conscientiousnessTrauma exposurePersonality assessmentPTSD riskProspective linksSymptom TotalPTSDLongitudinal associationsAURORA studyIncremental predictorNeuroticismTime pointsSymptomsTraitsAgreeablenessConscientiousnessAssociation of Psychological Safety with Burnout and Intent to Leave Among Physician Faculty in New York City
de Guillebon E, He C, Akhtar S, Pietrzak R, Ripp J, Peccoralo L. Association of Psychological Safety with Burnout and Intent to Leave Among Physician Faculty in New York City. Journal Of General Internal Medicine 2024, 1-7. PMID: 39354250, DOI: 10.1007/s11606-024-09034-9.Peer-Reviewed Original ResearchPhysician facultyAssociated with lower oddsAssociated with lower scoresAmbulatory care departmentPrevalence of PSClinical faculty membersStandard deviation unit increasePsychologically safe environmentMultivariate logistic regression analysisFaculty physiciansLogistic regression analysisHealth systemSeven-itemInstitution-wide surveyLower oddsConclusionsA majorityCare departmentNew York CityBurnoutPhysiciansSafe environmentFemale genderOrganization QuestionnaireLower scoresOccupational characteristicsSexual Orientation Moderates the Association Between Health Care Utilization-Related Factors and Mental Health Service Nonutilization Among United States Military Veterans
Chang C, Fischer I, Harper K, Livingston N, Depp C, Norman S, Pietrzak R. Sexual Orientation Moderates the Association Between Health Care Utilization-Related Factors and Mental Health Service Nonutilization Among United States Military Veterans. Psychological Services 2024 PMID: 39347751, DOI: 10.1037/ser0000907.Peer-Reviewed Original ResearchHeterosexual veteransSexual minority veteransHealth careMinority veteransMilitary veteransPsychiatric needsMental health treatment utilizationNational Health and ResilienceSource of health careSexual minoritiesVA health careUnited States military veteransU.S. military veteransMental health problemsNationally representative sampleSexual orientationNon-VADifficulties ScheduleVeterans StudyTreatment utilizationInfluence utilizationRepresentative sampleHealth problemsVeteransMental treatmentGambling and Substance Use Disorders in U.S. Military Veterans: Prevalence, Clinical Characteristics, and Suicide Risk
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Gambling and Substance Use Disorders in U.S. Military Veterans: Prevalence, Clinical Characteristics, and Suicide Risk. Journal Of Gambling Studies 2024, 40: 2119-2139. PMID: 39342537, DOI: 10.1007/s10899-024-10359-7.Peer-Reviewed Original ResearchSubstance use disordersU.S. military veteransMental health treatmentGambling groupSUD-onlySuicide riskHealth treatmentMilitary veteransNon-suicidal self-injuryLifetime substance use disorderNational Health and ResilienceRisk of substance use disordersSUD-only groupSelf-report measuresMental health difficultiesAdverse childhood experiencesMental health burdenPast-year gamblingSelf-injurySuicidality/self-harmVeterans StudyUse disorderNicotine dependenceTrauma variablesBehavioral correlatesMulti-modal risk factors differentiate suicide attempters from ideators in military veterans with major depressive disorder
Goldstein K, Pietrzak R, Challman K, Chu K, Beck K, Brenner L, Interian A, Myers C, Shafritz K, Szeszko P, Goodman M, Haznedar M, Hazlett E. Multi-modal risk factors differentiate suicide attempters from ideators in military veterans with major depressive disorder. Journal Of Affective Disorders 2024, 369: 588-598. PMID: 39341292, DOI: 10.1016/j.jad.2024.09.149.Peer-Reviewed Original ResearchSuicide attemptsDepressive disorderGo/No-GoMilitary veteransSeverity of suicidal behaviorFractional anisotropyDecreased attentional controlUnited States military veteransDiagnosis of MDDDSM-5 diagnosisMagnetic-resonance-imagingSuicide prevention effortsDifferentiate veteransDSM-5Attentional controlSuicide attempt/sSuicidal behaviorSuicidal ideationMDDNeurocognitive assessmentHealthy control groupNeuroimaging variablesPrevention effortsIdeationSuicideThe association of perceived social support, resilience, and posttraumatic stress symptoms among coronavirus disease patients in the United States
Li J, Wisnivesky J, Gonzalez A, Feder A, Pietrzak R, Chanumolu D, Hu L, Kale M. The association of perceived social support, resilience, and posttraumatic stress symptoms among coronavirus disease patients in the United States. Journal Of Affective Disorders 2024, 368: 390-397. PMID: 39293600, DOI: 10.1016/j.jad.2024.09.091.Peer-Reviewed Original ResearchCOVID-19-related posttraumatic stress disorderPosttraumatic stress disorderPre-existing mental disordersSocial supportMental disordersPosttraumatic Stress Disorder ChecklistPosttraumatic stress disorder symptomsRisk of posttraumatic stress disorderCD-RISCPosttraumatic stress symptomsAcute careAssociation of perceived social supportMedical Outcomes Study Social Support SurveyTargeting of preventive interventionsConnor-Davidson Resilience ScalePsychological consequences of COVID-19Low social supportSocial Support SurveyMeasures of resilienceDSM-5Associated with lower oddsStress disorderStress symptomsCross-sectional designPsychological resilienceAmygdala Cannabinoid 1 Receptor, Pain Response, and Emotional Numbing in Trauma-Exposed Individuals
Korem N, Hillmer A, D’Souza D, Nia A, Levy I, Pietrzak R, Harpaz-Rotem I. Amygdala Cannabinoid 1 Receptor, Pain Response, and Emotional Numbing in Trauma-Exposed Individuals. JAMA Network Open 2024, 7: e2432387. PMID: 39250156, PMCID: PMC11385051, DOI: 10.1001/jamanetworkopen.2024.32387.Peer-Reviewed Original ResearchAssociation patterns of antisocial personality disorder across substance use disorders
Low A, Stiltner B, Nunez Y, Adhikari K, Deak J, Pietrzak R, Kranzler H, Gelernter J, Polimanti R. Association patterns of antisocial personality disorder across substance use disorders. Translational Psychiatry 2024, 14: 346. PMID: 39198385, PMCID: PMC11358160, DOI: 10.1038/s41398-024-03054-z.Peer-Reviewed Original ResearchConceptsAntisocial personality disorderSubstance use disordersPersonality disorderUse disorderAssociation of antisocial personality disorderPresence of antisocial personality disorderPrevalence of antisocial personality disorderHazardous useDSM-5 SUD diagnosesSubstance use disorder severityDiagnostic criteriaInteraction effects with sexTobacco use disorderDSM-5Association of alcoholSUD diagnosisDisordersCocaineRacial/ethnic backgroundsIndividualsCocUDSeverityCannabisAssociation patternsAssociationMild Traumatic Brain Injury in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study
Meshberg-Cohen S, Cook J, Fischer I, Pietrzak R. Mild Traumatic Brain Injury in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study. Psychiatry 2024, 87: 314-328. PMID: 39186319, DOI: 10.1080/00332747.2024.2392226.Peer-Reviewed Original ResearchMild traumatic brain injuryNational Health and ResilienceU.S. military veteransPsychosocial functioningTraumatic brain injuryVeterans StudyMilitary veteransCurrent posttraumatic stress disorderOutcomes of mild traumatic brain injuryLifetime psychiatric conditionsGeneralized anxiety disorderComorbid psychiatric diagnosesPosttraumatic stress disorderPoor psychosocial functioningMild traumatic brain injury eventDrug use disordersBrain injuryPrevention of disabilityAssociated with increased oddsAnxiety disordersDepressive disorderStress disorderPsychiatric diagnosisMTBI symptomsPsychiatric characteristicsMicroglia-mediated neuroimmune suppression in PTSD is associated with anhedonia
Bonomi R, Hillmer A, Woodcock E, Bhatt S, Rusowicz A, Angarita G, Carson R, Davis M, Esterlis I, Nabulsi N, Huang Y, Krystal J, Pietrzak R, Cosgrove K. Microglia-mediated neuroimmune suppression in PTSD is associated with anhedonia. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2406005121. PMID: 39172786, PMCID: PMC11363315, DOI: 10.1073/pnas.2406005121.Peer-Reviewed Original ResearchConceptsPTSD groupPrefrontal-limbic circuitsNeuroimmune responseAssociated with anhedoniaPosttraumatic stress disorderPositron emission tomography brain imagingTranslocator protein availabilityBrain immune functionAnhedonic symptomsStress disorderPeripheral immune dysfunctionPTSDGroup differencesSeverity of symptomsPsychiatric diseasesTranslocator proteinBrain imagingAdministration of lipopolysaccharideSymptomsMicroglial markersLPS-induced increaseCompared to controlsImmune functionSickness symptomsAnhedoniaPersistent distress related to systemic racism among black veterans in the United States
Whealin J, Jegede O, Na P, Haeny A, Pietrzak R. Persistent distress related to systemic racism among black veterans in the United States. Journal Of Affective Disorders 2024, 365: 375-378. PMID: 39147153, DOI: 10.1016/j.jad.2024.08.052.Peer-Reviewed Original ResearchAdverse mental health sequelaeRisk of mental health problemsMilitary veteransIncreased risk of mental health problemsEthnic minority veteransSystemic racismMental health sequelaeMental health problemsUse of self-reportsEthnic minority populationsNationally representative sampleUS military veteransMultinomial logistic regression analysisSignificant emotional burdenStudy periodNon-veteransLogistic regression analysisEmotional burdenMinority veteransBlack veteransUS veteransHealth sequelaeBaseline assessmentHealthcare systemUS population