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Digital Therapists Get Stressed Too, Study Finds

A new study in NPJ Digital Medicine found OpenAI’s artificial intelligence tool ChatGPT shows signs of anxiety when its users share “traumatic narratives” about crime, war, or car accidents. And when chatbots get stressed out, they are less likely to be useful in therapeutic settings with people. Ziv Ben-Zion, PhD, postdoctoral fellow, is the study's first author.

Source: The New York Times
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  • To Expose or Not to Expose: A Comprehensive Perspective on Treatment for Posttraumatic Stress Disorder

    Arielle Rubenstein, PhD, clinical psychologist at Yale School of Music, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively, of a review in APA PsycNet that aims to answer the question of whether exposure is necessary to treat posttraumatic stress disorder by integrating clinical and research literature from multiple perspectives.

    Source: APA PsycNet
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  • Harpaz-Rotem to Speak at SOBP Symposium

    Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, has been invited to speak at the Neuroscience for Primetime Symposium at the Society of Biological Psychiatry (SOBP) Annual Meeting in May.

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  • Duek, Harpaz-Rotem Paper Named '2023 Leading Research Achievement' by BBRF

    The paper "In PTSD, Evidence That a Single Ketamine Infusion May Enhance Extinction of Recalled Traumatic Memories" by Or Duek, PhD, assistant professor adjunct in psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, has been named a 2023 Leading Research Achievement by the Brain & Behavior Research Foundation.

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  • Neural Patterns Differentiate Traumatic From Sad Autobiographical Memories in PTSD

    Investigators from Yale and Mount Sinai schools of medicine studied the neural activity of 28 people diagnosed with post-traumatic stress disorder (PTSD). They found that autobiographical memories for sad and neutral memories are processed differently in the brain than for traumatic memories. The findings were published in Nature Neuroscience. The co-senior author is Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology at Yale School of Medicine.

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  • Commentary: Post-Traumatic Stress Disorder: Rethinking Diagnosis

    Ian Fischer, PhD, postdoctoral fellow; Robert Pietrzak, PhD, MPH, professor of psychiatry and public health; and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are co-authors of a commentary in The Lancet Psychiatry that suggests post-traumatic stress disorder should be considered a lifetime diagnosis with remission periods.

    Source: The Lancet Psychiatry
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  • Long term Structural and Functional Neural Changes Following a Single Infusion of Ketamine in PTSD

    Or Duek, PhD, assistant professor adjunct of psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively of a study published in Neuropsychopharmacology that tests the potential of a single infusion of ketamine, followed by brief exposure therapy, to enhance post-retrieval extinction of post-traumatic stress disorder trauma memories.

    Source: Neuropsychopharmacology
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  • Neural Valuation of Rewards and Punishments in Posttraumatic Stress Disorder: A Computational Approach

    A new Yale study sought to unveil the neural mechanism which may govern deficits in decision making under uncertainty in posttraumatic stress disorder (PTSD). Investigators from the Yale PTSD Stress Lab, directed by Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, and the Yale Decision Neuroscience Lab, directed by Ifat Levy, PhD, associate professor and vice chair of diversity, equity and inclusion in comparative medicine, collaborated on the study, published in Translational Psychiatry.

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