2024
Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the AURORA study
Hyatt C, Reddi P, Sharpe B, Michopoulos V, van Rooij S, House S, Beaudoin F, An X, Stevens J, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Pascual J, Seamon M, Harris E, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, McLean S, Kessler R, Ressler K, Koenen K, Maples-Keller J. Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the AURORA study. Journal Of Research In Personality 2024, 112: 104524. DOI: 10.1016/j.jrp.2024.104524.Peer-Reviewed Original ResearchImpulsive personality traitsPTSD symptomsPersonality traitsOne-year post-traumaSevere PTSD symptomsPost-traumaFactor modelNegative urgencyLow agreeablenessLow conscientiousnessTrauma exposurePersonality assessmentPTSD riskProspective linksSymptom TotalPTSDLongitudinal associationsAURORA studyIncremental predictorNeuroticismTime pointsSymptomsTraitsAgreeablenessConscientiousnessRandomized controlled trial of two internet-based written therapies for world trade center workers and survivors with persistent PTSD symptoms
Feder A, Kowalchyk M, Brinkman H, Cahn L, Aaronson C, Böttche M, Presseau C, Fred-Torres S, Markowitz J, Litz B, Yehuda R, Knaevelsrud C, Pietrzak R. Randomized controlled trial of two internet-based written therapies for world trade center workers and survivors with persistent PTSD symptoms. Psychiatry Research 2024, 336: 115885. PMID: 38603979, DOI: 10.1016/j.psychres.2024.115885.Peer-Reviewed Original ResearchPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersWTC-related PTSD symptomsMental health-related functioningPTSD symptomsSymptom clustersHealth-related functioningPosttraumatic stress disorder's avoidancePosttraumatic stress disorder symptomsPosttraumatic Stress Disorder ChecklistPresent-centered therapyAssociated with significantly greater reductionsPersistent PTSD symptomsActive control interventionModerate-to-largeQuality of lifeSignificant main effectTreatment-by-time interactionWorld Trade Center survivorDSM-5PCL-5Stress disorderDepressive/anxiety symptomsWorld Trade CenterDepressive symptoms
2023
Evaluating a novel 8-factor dimensional model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Stiltner B, Fischer I, Duek O, Polimanti R, Harpaz-Rotem I, Pietrzak R. Evaluating a novel 8-factor dimensional model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Journal Of Affective Disorders 2023, 346: 303-307. PMID: 37979626, DOI: 10.1016/j.jad.2023.11.041.Peer-Reviewed Original ResearchConceptsIndex traumaPTSD symptomsNational HealthPosttraumatic stress disorder (PTSD) symptomsVeterans StudyMilitary veteransTrauma-exposed populationsClinician-administered interviewU.S. military veteransConfirmatory factor analysisDSM-5 modelStrong significant associationTrauma exposureIntrusive symptomsDisorder symptomsCombat exposureHigh riskU.S. veteransDSM-5Significant associationSymptomsInterpersonal violenceFactor analysisPTSDScarce researchPosttraumatic Growth in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study
Kang H, Fischer I, Dickinson S, Na P, Tsai J, Tedeschi R, Pietrzak R. Posttraumatic Growth in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study. Psychiatric Quarterly 2023, 95: 17-32. PMID: 37938492, DOI: 10.1007/s11126-023-10061-8.Peer-Reviewed Original ResearchPosttraumatic growthU.S. military veteransPTSD symptomsTraumatic eventsPosttraumatic stress disorder (PTSD) symptomsPositive psychological changesVeterans StudyMilitary veteransGreater posttraumatic growthTrauma-exposed veteransIntrinsic religiosityPTSD symptom severitySevere PTSD symptomsHigh-risk sampleIntrusive symptomsDisorder symptomsPsychological changesPTG levelsTraumatic experiencesPTSD ChecklistVeteran samplePsychosocial characteristicsSymptom clustersDSM-5Symptom severityClinical significance of novel 8-factor model of DSM-5 PTSD in national VA PTSD residential treatment data: Internally- v. externally-cued intrusions
Gross G, Spiller T, Duek O, Pietrzak R, Harpaz-Rotem I. Clinical significance of novel 8-factor model of DSM-5 PTSD in national VA PTSD residential treatment data: Internally- v. externally-cued intrusions. Journal Of Affective Disorders 2023, 328: 255-260. PMID: 36806596, DOI: 10.1016/j.jad.2023.02.046.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPTSD symptomsDysphoric arousalDSM-5 posttraumatic stress disorderDSM-5 PTSD symptomsDistinct underlying processesSelf-report measuresGeneralized anxiety symptomsSuperior model fitPhysical health functioningCore defining featuresStructural equation modelingWorse emotional functioningAnxious arousalSymptoms of depressionNegative affectIntrusion symptomsGreater avoidanceEmotional functioningStress disorderAnxiety symptomsPTSD ChecklistIntrusion factorCross-sectional designGeneralized anxietyStructural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Harnett N, Fani N, Carter S, Sanchez L, Rowland G, Davie W, Guzman C, Lebois L, Ely T, van Rooij S, Seligowski A, Winters S, Grasser L, Musey P, Seamon M, House S, Beaudoin F, An X, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Swor R, Hudak L, Pascual J, Harris E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Kessler R, Koenen K, McLean S, Jovanovic T, Stevens J, Ressler K. Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure. Molecular Psychiatry 2023, 28: 2975-2984. PMID: 36725899, PMCID: PMC10615735, DOI: 10.1038/s41380-023-01971-x.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderAmygdala connectivityAmygdala reactivityTrauma exposurePrefrontal cortexPTSD symptomsDorsal anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingGreater amygdala connectivityDorsolateral prefrontal cortexSymptoms 3Trauma outcomesSkin conductance levelCingulate cortexEthnic groupsEthnic disparitiesResonance imagingMultisite longitudinal studyStress disorderTwo weeksEthnic variabilityWhite individualsBlack participants
2021
Internet-based cognitive behavioral therapy versus internet-based modified present-centered therapy for world trade center responders and survivors with posttraumatic stress disorder: rationale and design of a randomized controlled trial
Brinkman H, Kowalchyk M, Cahn L, Aaronson C, Böttche M, Presseau C, Markowitz J, Litz B, Huckins L, Yehuda R, Knaevelsrud C, Pietrzak R, Feder A. Internet-based cognitive behavioral therapy versus internet-based modified present-centered therapy for world trade center responders and survivors with posttraumatic stress disorder: rationale and design of a randomized controlled trial. International Journal Of Clinical Trials 2021, 8: 202-210. DOI: 10.18203/2349-3259.ijct20212843.Peer-Reviewed Original ResearchInternet-based cognitive behavioral therapyCognitive behavioral therapyBehavioral therapyActive comparison treatmentsWorld Trade Center respondersPosttraumatic stress disorder (PTSD) symptomsEvidence-based treatmentsDesign of trialsQuality of lifeTrauma-affected populationsPost-traumatic growthPosttraumatic stress disorderWTC rescueThird variable explanationsActive treatmentWTC workersComorbid depressiveWTC respondersTreatment responseCBT trialsCBT interventionTherapyPTSD symptomsRecovery workersCBT studies60558 Non-Suicidal Self Injury in Military Veterans with PTSD: An Ecological Momentary Assessment Study
Kachadourian L, Sullivan T, Pietrzak R. 60558 Non-Suicidal Self Injury in Military Veterans with PTSD: An Ecological Momentary Assessment Study. Journal Of Clinical And Translational Science 2021, 5: 139-140. PMCID: PMC8828001, DOI: 10.1017/cts.2021.757.Peer-Reviewed Original ResearchPost-traumatic stress disorderEcological momentary assessmentPTSD symptomsMilitary veteransStress disorderNon-Suicidal Self-InjuryPost-traumatic stress disorder symptomsNumber of symptomsCurrent pilot studySurvey completion rateMomentary assessmentNSSI urgesEligible participantsSpecific symptomsEcological momentary assessment studySymptomsMilitary populationMomentary assessment studySelf-InjuryPilot studyTreatment effortsStudy periodLarge-scale studiesSurvey completionDisorder symptoms
2020
Beyond stigma: Understanding the “inclined abstainers” in military behavioral health-care utilization
Aikins D, Pietrzak R, Geraci J, Benham T, Morrissey P, Southwick S. Beyond stigma: Understanding the “inclined abstainers” in military behavioral health-care utilization. Military Psychology 2020, 32: 419-427. PMID: 38536308, PMCID: PMC10013392, DOI: 10.1080/08995605.2020.1784822.Peer-Reviewed Original ResearchPosttraumatic stress disorderPTSD symptomsInclined abstainersNegative beliefsActive duty soldiersCombat-related posttraumatic stress disorderLow treatment utilizationMeasures of stigmaDuty soldiersMental health-related problemsTreatment utilizationInclined actorsStress disorderTreatment beliefsTreatment modelBehavioral health care utilizationBeliefsArmy postPsychotherapyHealth-related problemsGreater severityEngagementResilienceTreatment intentionStigma
2018
Sex Differences in Correlates of Risk and Resilience Associated with Military Sexual Trauma
Averill L, Smith N, Holens P, Sippel L, Bellmore A, Mota N, Sareen J, Southwick S, Pietrzak R. Sex Differences in Correlates of Risk and Resilience Associated with Military Sexual Trauma. Journal Of Aggression Maltreatment & Trauma 2018, 28: 1199-1215. DOI: 10.1080/10926771.2018.1522408.Peer-Reviewed Original ResearchMilitary sexual traumaMST survivorsDrug use disordersPTSD symptomsSexual traumaHistory of MSTUse disordersMental health treatment utilizationPTSD symptom severityLifetime traumatic eventsLifetime PTSD symptomsPhysical health outcomesPotential sex-based differencesSuicidal ideation/attemptsSex differencesRepresentative National HealthCorrelates of riskTraumatic eventsSex-based differencesResilience factorsPsychosocial correlatesUnderstanding of outcomesResilience AssociatedNational HealthTreatment utilization
2017
Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Mota NP, Han S, Harpaz‐Rotem I, Maruff P, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH. Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Depression And Anxiety 2017, 35: 168-177. PMID: 29172227, PMCID: PMC5794529, DOI: 10.1002/da.22698.Peer-Reviewed Original ResearchConceptsΕ4 allele carriersApolipoprotein E gene polymorphismE gene polymorphismTrauma burdenU.S. military veteransAllele carriersPosttraumatic stress disorderPTSD symptomsNational HealthGreater social supportGene polymorphismsGreater severityMilitary veteransVeterans StudyAPOE ε4 carrier statusSocial supportΕ4 carrier statusAPOE genotypeΕ4 noncarriersPosttraumatic stress symptomsIndependent replication sampleSymptomsPTSD riskStress disorderCarrier status
2014
Functional significance of a novel 7-factor model of DSM-5 PTSD symptoms: Results from the National Health and Resilience in Veterans Study
Pietrzak RH, Tsai J, Armour C, Mota N, Harpaz-Rotem I, Southwick SM. Functional significance of a novel 7-factor model of DSM-5 PTSD symptoms: Results from the National Health and Resilience in Veterans Study. Journal Of Affective Disorders 2014, 174: 522-526. PMID: 25556669, DOI: 10.1016/j.jad.2014.12.007.Peer-Reviewed Original ResearchConceptsQuality of lifePosttraumatic stress disorderDSM-5 PTSD symptomsPTSD symptomsNational HealthU.S. veteransSuicidal ideationVeterans StudySymptom clustersDysphoric arousal symptomsCross-sectional designFunctional outcomePsychiatric comorbidityClinical significancePTSD symptom clustersCurrent depressionDSM-5 PTSD symptom clustersPTSD phenotypeMental disordersSymptomsComorbid psychopathologyStress disorderFunctional correlatesStatistical ManualTreatment efforts
2011
Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: A confirmatory factor analytic study
Pietrzak RH, Tsai J, Harpaz-Rotem I, Whealin JM, Southwick SM. Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: A confirmatory factor analytic study. Journal Of Psychiatric Research 2011, 46: 317-322. PMID: 22154134, DOI: 10.1016/j.jpsychires.2011.11.013.Peer-Reviewed Original ResearchConceptsIraq/Afghanistan veteransHyperarousal symptom clustersConfirmatory factor analytic studyFactor analytic studiesAfghanistan veteransDysphoric arousalPTSD symptomsArousal clustersCommunity samplePosttraumatic stress disorder (PTSD) symptomsEmotional numbing modelSymptom clustersTreatment-seeking samplePosttraumatic stress symptomsDSM-IV modelIndependent samplesFive-factor modelConfirmatory factor analysisAnxious arousalEmotional numbingNumbing modelPTSD symptomatologyDisorder symptomsStress symptomsPTSD Checklist