2024
Health correlates of experiential and behavioral avoidance among trauma-exposed veterans
Schwartz E, Palmisano A, Petrakis I, Pietrzak R, Sofuoglu M. Health correlates of experiential and behavioral avoidance among trauma-exposed veterans. Journal Of Psychiatric Research 2024, 176: 213-217. PMID: 38878649, DOI: 10.1016/j.jpsychires.2024.06.014.Peer-Reviewed Original ResearchTrauma-exposed veteransExperiential avoidanceBehavioral avoidanceAnxiety symptomsDepressive symptomsMental health outcomesCognitive dysfunctionPhysical healthPhysical health outcomesHealth outcomesQuality of lifeHealth-related dysfunctionTrauma historyPsychosocial functioningCognitive functionAvoidance behaviorOutcome measuresHealth-related quality of lifeTreatment targetDistressExploratory analysisVeteransHealth-related qualityAvoidanceAnxietyGeneralized anxiety and mild anxiety symptoms in U.S. military veterans: Prevalence, characteristics, and functioning
Macdonald-Gagnon G, Stefanovics E, Potenza M, Pietrzak R. Generalized anxiety and mild anxiety symptoms in U.S. military veterans: Prevalence, characteristics, and functioning. Journal Of Psychiatric Research 2024, 171: 263-270. PMID: 38325107, DOI: 10.1016/j.jpsychires.2024.02.013.Peer-Reviewed Original ResearchConceptsGeneralized anxiety disorderMild anxiety symptomsAnxiety symptomsMilitary veteransU.S. veteransCorrelates of generalized anxiety disorderCorrelates of anxiety symptomsAnxiety symptom severityU.S. military veteransAnxiety disordersGeneralized anxietyPoor mental healthSuicidal thoughtsSymptom severityMental disordersExcessive anxietyAnxietyMagnitude associationsMental healthFunctional impairmentVeteransFunctional correlatesClinical samplesNationally representative sampleSymptoms
2023
Clinical significance of novel 8-factor model of DSM-5 PTSD in national VA PTSD residential treatment data: Internally- v. externally-cued intrusions
Gross G, Spiller T, Duek O, Pietrzak R, Harpaz-Rotem I. Clinical significance of novel 8-factor model of DSM-5 PTSD in national VA PTSD residential treatment data: Internally- v. externally-cued intrusions. Journal Of Affective Disorders 2023, 328: 255-260. PMID: 36806596, DOI: 10.1016/j.jad.2023.02.046.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPTSD symptomsDysphoric arousalDSM-5 posttraumatic stress disorderDSM-5 PTSD symptomsDistinct underlying processesSelf-report measuresGeneralized anxiety symptomsSuperior model fitPhysical health functioningCore defining featuresStructural equation modelingWorse emotional functioningAnxious arousalSymptoms of depressionNegative affectIntrusion symptomsGreater avoidanceEmotional functioningStress disorderAnxiety symptomsPTSD ChecklistIntrusion factorCross-sectional designGeneralized anxiety
2022
Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma
Harnett N, Dumornay N, Delity M, Sanchez L, Mohiuddin K, Musey P, Seamon M, McLean S, Kessler R, Koenen K, Beaudoin F, Lebois L, van Rooij S, Sampson N, Michopoulos V, Maples-Keller J, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, McGrath M, Hudak L, Pascual J, House S, An X, Stevens J, Neylan T, Jovanovic T, Linnstaedt S, Germine L, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Smoller J, Luna B, Harte S, Elliott J, Ressler K. Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma. Psychological Medicine 2022, 53: 2553-2562. PMID: 35094717, PMCID: PMC9339026, DOI: 10.1017/s0033291721004475.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPrevious trauma exposureTrauma exposurePosttraumatic depressionPrior differencesChildhood emotional abusePrior trauma exposureSelf-report assessmentsWhite participantsPosttraumatic stressStress disorderAnxiety symptomsEmotional abuseLife stressorsPTSD ratesEarly aftermathPosttraumatic dysfunctionAnxietySymptom trajectoriesRecent traumaEthnic differencesAURORA studyParticipantsSymptom recoveryRecent research
2015
Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study
Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, Lautenschlager NT, Restrepo C, Martins RN, Masters CL, Villemagne VL, Rowe CC, Maruff P. Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study. JAMA Psychiatry 2015, 72: 284-291. PMID: 25629787, DOI: 10.1001/jamapsychiatry.2014.2476.Peer-Reviewed Original ResearchConceptsPreclinical Alzheimer's diseaseSubjective memory complaintsElevated anxiety symptomsVerbal memoryExecutive functionGlobal cognitionAnxiety symptomsCognitive declineCognitive changesMemory complaintsAβ statusDepressive symptomsLow anxiety groupComprehensive neuropsychological evaluationHigh anxiety groupRole of anxietyFlorbetapir F 18Visual memoryCognitive domainsVisuospatial abilitiesMild cognitive impairmentNeuropsychological evaluationCognitive functionProspective cohort studyMore rapid decline