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Marco Galimberti, PhD, postdoctoral associate, and Joel Gelernter, MD, Foundations Fund Professor of Psychiatry and Professor of Genetics and of Neuroscience, are first and senior authors, respectively, of a paper on Molecular Psychiatry that investigates the genetic architecture and causal relationships between cannabis use disorder and lifetime cannabis use with risk for developing substance use disorders and substance use traits.
- December 07, 2023
A study led by VA Connecticut Healthcare Center/Yale researchers reveals ancestries around the world possess a shared genetic architecture for problematic alcohol use – habitual heavy drinking, accompanied by harmful consequences. Hang Zhou, PhD, assistant professor of psychiatry and of biomedical informatics & data science at Yale School of Medicine and VA Connecticut, and Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, and professor of genetics and of neuroscience at Yale School of Medicine and VA Connecticut, were first and senior authors, respectively.
- September 22, 2023Source: Psychological Medicine
Peter Na, MD, MPH, assistant professor of psychiatry, and Robert Pietrzak, PhD, MPH, professor of psychiatry and of public health, led a research team that examined the psychosocial moderators of high alcohol consumption determined by polygenic risk in military veterans.
- October 27, 2022
A new study led by Yale scientists has identified genetic risk factors associated with habitual heavy drinking.
- February 20, 2022Source: Translational Psychiatry
Several Yale researchers, including first author Janitza Montalvo-Ortiz, PhD, and senior author Robert Pietrzak, PhD, MPH, conducted the largest epi-genomewide association study of post-traumatic stress disorder in veterans. Their findings were published in Translational Psychiatry.
- September 20, 2020Source: Brain & Behavior Research Foundation
A genome-wide analysis of over 435,000 individuals of European ancestry has revealed 19 new locations in the human genome where common DNA variations significantly raise risk for problematic drinking. It also linked pathological drinking with elevated risk of many psychiatric disorders, including depression and schizophrenia.
- September 03, 2020
Joel Gelernter, MD, Foundations Fund Professor of Psychiatry and Professor of Genetics and of Neuroscience; and Renato Polimanti, PhD, Assistant Professor of Psychiatry, will co-lead the journal Complex Psychiatry, which recently changed its name from Molecular Neuropsychiatry.
- April 02, 2019
Heavy drinkers and alcoholics share genetic similarities but also exhibit key differences, a massive new genome-wide analysis published April 2 in the journal Nature Communications found.
- September 04, 2018
Eight Yale neuroscientists have been awarded research grants through the Brain & Behavior Research Foundation’s NARSAD Young Investigator Grant Program.
- October 26, 2017
A gene variant involved in brain development is strongly associated with the risk of developing both major depression and alcoholism in African Americans, according to a new genome-wide association study (GWAS) by Yale and University of Pennsylvania researchers, published Oct. 25 in the journal JAMA Psychiatry.