Publications
2024
- Wnt Signaling in Atherosclerosis: Mechanisms to Therapeutic Implications.Afroz R, Goodwin JE. Biomedicines. 2024 Jan 25; 2024 Jan 25. PMID: 38397878.
2023
- Lessons Learned from the Connecticut Response to COVID-19 in Nursing Homes during the First 2 Years of the Pandemic.Goodwin J, Harizaj A, Armstrong J, Maloney M, Ehrlich H, Leung V, Parikh S. J Am Med Dir Assoc. 2023 Oct; 2023 Aug 14. PMID: 37591486.
- Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in db/db mice.Srivastava SP, Goodwin JE. Am J Physiol Renal Physiol. 2023 Oct 1; 2023 Aug 17. PMID: 37589053.
- Endothelial Dysfunction in Cardiorenal Conditions: Implications of Endothelial Glucocorticoid Receptor-Wnt Signaling.Akhter MS, Goodwin JE. Int J Mol Sci. 2023 Sep 19; 2023 Sep 19. PMID: 37762564.
- Editorial: Steroid hormone receptors in cardiometabolic disease.Goodwin J, Odermatt A, Morgan R, Nixon M. Front Endocrinol (Lausanne). 2023; 2023 Jul 19. PMID: 37538788.
- Tracking antimalarial drug resistance using mosquito blood meals: a cross-sectional study.Ehrlich HY, Somé AF, Bazié T, Ebou CN, Dembélé EL, Balma R, Goodwin J, Wade M, Bei AK, Ouédraogo JB, Foy BD, Dabiré RK, Parikh S. Lancet Microbe. 2023 Jun; 2023 Apr 20. PMID: 37086737.
- Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in db/db mice.Srivastava SP, Goodwin JE. bioRxiv. 2023 Mar 23; 2023 Mar 23. PMID: 36993478.
- Hypomorphic PKD1 Alleles Impact Disease Variability in Autosomal Dominant Polycystic Kidney Disease.Gulati A, Dahl NK, Hartung EA, Clark SL, Moudgil A, Goodwin J, Somlo S. Kidney360. 2023 Mar 1. PMID: 36706243.
- Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda.Kay K, Goodwin J, Ehrlich H, Ou J, Freeman T, Wang K, Li F, Wade M, French J, Huang L, Aweeka F, Mwebaza N, Kajubi R, Riggs M, Ruiz-Garcia A, Parikh S. Clin Pharmacol Ther. 2023 Mar; 2022 Nov 14. PMID: 36260349.
- The Impact of Extended Treatment With Artemether-lumefantrine on Antimalarial Exposure and Reinfection Risks in Ugandan Children With Uncomplicated Malaria: A Randomized Controlled Trial.Whalen ME, Kajubi R, Goodwin J, Orukan F, Colt M, Huang L, Richards K, Wang K, Li F, Mwebaza N, Aweeka FT, Parikh S. Clin Infect Dis. 2023 Feb 8. PMID: 36130191.
2022
- Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5.Mangou K, Moore AJ, Thiam LG, Ba A, Orfanó A, Desamours I, Ndegwa DN, Goodwin J, Guo Y, Sheng Z, Patel SD, Diallo F, Sene SD, Pouye MN, Faye AT, Thiam A, Nunez V, Diagne CT, Sadio BD, Shapiro L, Faye O, Mbengue A, Bei AK. Sci Rep. 2022 Nov 12; 2022 Nov 12. PMID: 36371450.
- Clinical characteristics of Plasmodium falciparum infection among symptomatic patients presenting to a major urban military hospital in Cameroon.Hodson DZ, Mbarga Etoundi Y, Mbatou Nghokeng N, Mohamadou Poulibe R, Magne Djoko S, Goodwin J, Cheteug Nguesta G, Nganso T, Armstrong JN, Andrews JJ, Zhang E, Wade M, Eboumbou Moukoko CE, Boum Y 2nd, Parikh S. Malar J. 2022 Oct 22; 2022 Oct 22. PMID: 36273147.
- Fanconi syndrome, nephrotic-range proteinuria, and hypoalbuminemia in a newborn-Occam's razor or Hickam's dictum? Answers.Nugent JT, Reardon J, Crana C, Greenberg JH, Warejko JK, Goodwin JE. Pediatr Nephrol. 2022 Jan; 2021 Oct 11. PMID: 34633532.
- Fanconi syndrome, nephrotic-range proteinuria, and hypoalbuminemia in a newborn-Occam's razor or Hickam's dictum? Questions.Nugent JT, Reardon J, Crana C, Greenberg JH, Warejko JK, Goodwin JE. Pediatr Nephrol. 2022 Jan; 2021 Oct 11. PMID: 34633531.
2021
- Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus.Srivastava SP, Zhou H, Setia O, Dardik A, Fernandez-Hernando C, Goodwin J. J Am Heart Assoc. 2021 Aug 3; 2021 Jul 26. PMID: 34308664.
- Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway.Liu B, Zhou H, Zhang T, Gao X, Tao B, Xing H, Zhuang Z, Dardik A, Kyriakides TR, Goodwin JE. Angiogenesis. 2021 Aug; 2021 Mar 2. PMID: 33650028.
- Coronavirus Disease (COVID)-19 and Diabetic Kidney Disease.Srivastava SP, Srivastava R, Chand S, Goodwin JE. Pharmaceuticals (Basel). 2021 Jul 30; 2021 Jul 30. PMID: 34451848.
- Editorial: Combating Diabetes and Diabetic Kidney Disease.Srivastava SP, Kanasaki K, Goodwin JE. Front Pharmacol. 2021; 2021 Jul 8. PMID: 34305620.
- Interactions among Long Non-Coding RNAs and microRNAs Influence Disease Phenotype in Diabetes and Diabetic Kidney Disease.Srivastava SP, Goodwin JE, Tripathi P, Kanasaki K, Koya D. Int J Mol Sci. 2021 Jun 2; 2021 Jun 2. PMID: 34199672.
- Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys.Srivastava SP, Li J, Takagaki Y, Kitada M, Goodwin JE, Kanasaki K, Koya D. iScience. 2021 May 21; 2021 Apr 6. PMID: 33981977.
- Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy.Srivastava SP, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, Dardik A, Fernandez-Hernando C, Goodwin J. Nat Commun. 2021 Apr 22; 2021 Apr 22. PMID: 33888696.
2020
- Loss of Mitochondrial Control Impacts Renal Health.Srivastava SP, Kanasaki K, Goodwin JE. Front Pharmacol. 2020; 2020 Dec 9. PMID: 33362536.
- Metabolic reprogramming by N-acetyl-seryl-aspartyl-lysyl-proline protects against diabetic kidney disease.Srivastava SP, Goodwin JE, Kanasaki K, Koya D. Br J Pharmacol. 2020 Aug; 2020 Jun 22. PMID: 32352559.
- Cancer Biology and Prevention in Diabetes.Srivastava SP, Goodwin JE. Cells. 2020 Jun 2; 2020 Jun 2. PMID: 32498358.
- Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs.Srivastava SP, Goodwin JE, Kanasaki K, Koya D. Genes (Basel). 2020 Feb 18; 2020 Feb 18. PMID: 32085655.
- Endothelial cell-glucocorticoid receptor interactions and regulation of Wnt signaling.Zhou H, Mehta S, Srivastava SP, Grabinska K, Zhang X, Wong C, Hedayat A, Perrotta P, Fernández-Hernando C, Sessa WC, Goodwin JE. JCI Insight. 2020 Feb 13; 2020 Feb 13. PMID: 32051336.
- The Effect of Glucocorticoids on Angiogenesis in the Treatment of Solid Tumors.Liu B, Goodwin JE. J Cell Signal. 2020. PMID: 32728672.
2019
- Diagnosis, Treatment, and Outcomes in Children With Congenital Nephrogenic Diabetes Insipidus: A Pediatric Nephrology Research Consortium Study.D'Alessandri-Silva C, Carpenter M, Ayoob R, Barcia J, Chishti A, Constantinescu A, Dell KM, Goodwin J, Hashmat S, Iragorri S, Kaspar C, Mason S, Misurac JM, Muff-Luett M, Sethna C, Shah S, Weng P, Greenbaum LA, Mahan JD. Front Pediatr. 2019; 2020 Jan 21. PMID: 32039113.
- Characterization of Circular RNA and microRNA Profiles in Septic Myocardial Depression: a Lipopolysaccharide-Induced Rat Septic Shock Model.Zhang TN, Yang N, Goodwin JE, Mahrer K, Li D, Xia J, Wen R, Zhou H, Zhang T, Song WL, Liu CF. Inflammation. 2019 Dec. PMID: 31332662.
- The Glucocorticoid Receptor in Cardiovascular Health and Disease.Liu B, Zhang TN, Knight JK, Goodwin JE. Cells. 2019 Oct 9; 2019 Oct 9. PMID: 31601045.
- Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression.Zhang TN, Goodwin JE, Liu B, Li D, Wen R, Yang N, Xia J, Zhou H, Zhang T, Song WL, Liu CF. Mol Ther Nucleic Acids. 2019 Sep 6; 2019 Aug 5. PMID: 31472370.
- microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney.Srivastava SP, Hedayat AF, Kanasaki K, Goodwin JE. Front Pharmacol. 2019; 2019 Aug 16. PMID: 31474862.
- Role of the glucocorticoid receptor in glomerular disease.Goodwin JE. Am J Physiol Renal Physiol. 2019 Jul 1; 2019 Jun 5. PMID: 31166704.
2018
- SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis.Srivastava SP, Li J, Kitada M, Fujita H, Yamada Y, Goodwin JE, Kanasaki K, Koya D. Cell Death Dis. 2018 Sep 24; 2018 Sep 24. PMID: 30250024.
2017
- Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury.Zhou H, Tian X, Tufro A, Moeckel G, Ishibe S, Goodwin J. Sci Rep. 2017 Aug 29; 2017 Aug 29. PMID: 28852159.
2015
- Endothelial glucocorticoid receptor suppresses atherogenesis--brief report.Goodwin JE, Zhang X, Rotllan N, Feng Y, Zhou H, Fernández-Hernando C, Yu J, Sessa WC. Arterioscler Thromb Vasc Biol. 2015 Apr; 2015 Feb 19. PMID: 25810297.
- Glucocorticoids and the Cardiovascular System.Goodwin JE. Adv Exp Med Biol. 2015. PMID: 26216000.
2014
- Loss of the endothelial glucocorticoid receptor prevents the therapeutic protection afforded by dexamethasone after LPS.Goodwin JE, Feng Y, Velazquez H, Zhou H, Sessa WC. PLoS One. 2014; 2014 Oct 9. PMID: 25299055.
2013
- Abdominal distention and renal failure in a neonate.Bedri B, Goodwin JE. BMJ Case Rep. 2013 Feb 20; 2013 Feb 20. PMID: 23429016.
- Endothelial glucocorticoid receptor is required for protection against sepsis.Goodwin JE, Feng Y, Velazquez H, Sessa WC. Proc Natl Acad Sci U S A. 2013 Jan 2; 2012 Dec 17. PMID: 23248291.
2012
- Glucocorticoid-induced hypertension.Goodwin JE, Geller DS. Pediatr Nephrol. 2012 Jul; 2011 Jul 9. PMID: 21744056.
2011
- Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension.Goodwin JE, Zhang J, Gonzalez D, Albinsson S, Geller DS. J Hypertens. 2011 Jul. PMID: 21659825.
2010
- The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension.Goodwin JE, Zhang J, Velazquez H, Geller DS. Biochem Biophys Res Commun. 2010 Apr 2; 2010 Feb 24. PMID: 20188070.
2009
- Characterization of a novel gain of function glucocorticoid receptor knock-in mouse.Zhang J, Ge R, Matte-Martone C, Goodwin J, Shlomchik WD, Mamula MJ, Kooshkabadi A, Hardy MP, Geller D. J Biol Chem. 2009 Mar 6; 2008 Nov 18. PMID: 19017639.
2008
- A critical role for vascular smooth muscle in acute glucocorticoid-induced hypertension.Goodwin JE, Zhang J, Geller DS. J Am Soc Nephrol. 2008 Jul; 2008 Apr 23. PMID: 18434569.
Book Chapters
Goodwin JE. (2017) Endothelial Dysfunction and Vascular Remodeling in Hypertension. In: Flynn J, Ingelfinger JR, Redwine K (Eds.) Pediatric Hypertension, Springer International Publishing AG, DOI: 10.1007/978-3-319-31420-4_41.
Geller DS and Goodwin JE: Monogenic Disorders of Blood Pressure Regulation. In: Dominiczak AF, Connell JM (Eds.) Handbook of Hypertension, 2007; Vol 24, 29-47.