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All Publications

Representative Publications

Zimmermann M*, Zimmermann-Kogadeeva M*, Wegmann R, Goodman AL: Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature. 2019 Jun 3. doi: 10.1038/s41586-019-1291-3. PMID: 31158845 (* equal contribution)

Zimmermann M*, Zimmermann-Kogadeeva M*, Wegmann R, Goodman AL: Separating host and microbiome contributions to drug pharmacokinetics and toxicity. Science. 2019 Feb 8;363(6427). pii: eaat9931. doi: 10.1126/science.aat9931. Epub 2019 Feb 7. PMID: 30733391 (* equal contribution)

Wexler AG, Schofield WB, Degnan PH, Folta-Stogniew E, Barry NA, Goodman AL: Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins. ELife. 2018 Sep 18;7. pii: e37138. doi: 10.7554/eLife.37138. PMID: 30226189

Schofield WB*, Zimmermann-Kogadeeva M*, Zimmermann M, Barry NA, Goodman AL: The Stringent Response Determines the Ability of a Commensal Bacterium to Survive Starvation and to Persist in the Gut. Cell Host Microbe. 24(1) p120-132 (2018). PMID: 30008292 (* equal contribution)

Lim B, Zimmermann M, Barry NA, Goodman AL: Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut. Cell. 169(3) p547-558 (2017). PMID: 28431252

Wexler AG, Bao Y, Whitney JC, Bobay LM, Xavier JB, Schofield WB, Barry NA, Russell AB, Tran BQ, Goo YA, Goodlett DR, Ochman H, Mougous JD, Goodman AL: Human symbionts inject and neutralize antibacterial toxins to persist in the gut. PNAS. 133(13) p3638-44 (2016). PMID: 26957597

Cullen TW, Schofield WB, Barry NA, Putnam EE, Rundell EA, Trent MS, Degnan PH, Booth CJ, Yu H, Goodman AL: Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation. Science. 347(6218) p170-175 (2015). PMID: 25574022

Goodman AL, Kallstrom G, Faith JJ, Reyes A, Moore A, Dantas G, Gordon JI: Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. PNAS. 108(15) p6252-6257 (2011). PMID: 21436049

Goodman AL, McNulty NP, Zhao Y, Leip D, Mitra RD, Lozupone CA, Knight R, Gordon JI: Identifying genetic determinants needed to establish a human gut symbiont in its habitat. Cell Host Microbe. 6(3) p279-289 (2009). PMID: 19748469

Goodman AL, Kulasekara B, Rietsch A, Boyd D, Smith RS, Lory S: A signaling network reciprocally regulates genes associated with acute infection and chronic persistence in Pseudomonas aeruginosa. Dev Cell. 7(5) p745-754 (2004). PMID: 15525535

Recent Reviews

Wexler AG, Goodman AL: An insider's perspective: Bacteroides as a window into the microbiome. Nat Microbiol. 2:17026 p1-11 (2017). PMID: 28440278

Dantas G, Sommer MO, Degnan PH, Goodman AL: Experimental approaches for defining the functional roles of microbes in the human gut. Ann Rev Microbiol. 67 p459-475 (2013). PMID: 24024637