2018
Stress and Addiction
Sinha R. Stress and Addiction. 2018, 299-311. DOI: 10.4324/9781315689197-25.Peer-Reviewed Original ResearchExecutive control functionsNegative emotional statesChronic stressEarly life stressCortical brain regionsEmotional statesAddiction vulnerabilityStressful situationsMesolimbic dopamine pathwayLife stressAddiction severityBrain regionsType of adaptationDrug useDopamine pathwayAlters activityRelapse riskEmotionsIndividualsDistressControl functionsAddictionAbuseBehaviorStress
2017
Chapter 69 Patient Responses to Guanfacine in Cocaine Addiction
Milivojevic V, Sinha R, Fox H. Chapter 69 Patient Responses to Guanfacine in Cocaine Addiction. 2017, 679-688. DOI: 10.1016/b978-0-12-803750-8.00069-5.ChaptersAnxiety pathophysiologyDrugs of abuseNeural stress systemsDrug-seeking behaviorEmotional controlDrug seekingRecent research findingsChronic stress stateNegative consequencesCocaine addictionCocaine dependenceStress systemResearch findingsLong-term agentsCocaine useDrug useAbuseGuanfacineCravingSeekingStress sensitivityAddictionAbilityRobust adaptationOwn laboratory
2005
96 Alcohol Abuse and Eating Disorders
Schwartz M, Sinha R. 96 Alcohol Abuse and Eating Disorders. 2005, 1263-1275. DOI: 10.1016/b978-012564370-2/50098-2.Peer-Reviewed Original ResearchAlcohol abusePossible etiological factorsClinical treatment researchRelevant control groupsEtiological factorsTreatment approachesControl groupBulimia nervosaAnorexia nervosaClinical settingPatientsSignificant subgroupEating DisordersDisordersOverall rateTreatment researchCommunity sampleTreatmentNervosaAbuseEDPrevalenceChapter 3.7 Stress and drug abuse
Sinha R. Chapter 3.7 Stress and drug abuse. Techniques In The Behavioral And Neural Sciences 2005, 15: 333-356. DOI: 10.1016/s0921-0709(05)80063-x.Peer-Reviewed Original ResearchRole of stressAddictive processDrug abuseMost major theoriesDrug-seeking behaviorStress-related copingFuture researchModels of addictionHuman laboratory studiesField of addictionSubstantial preclinical dataChronic drug abuseDrug useTreatment developmentMajor theoriesCurrent knowledge baseStress exposureAbuseLittle direct evidenceAddictionEmpirical evidencePreclinical dataCopingEpidemiological studiesClinical observations
2001
How does stress increase risk of drug abuse and relapse?
Sinha R. How does stress increase risk of drug abuse and relapse? Psychopharmacology 2001, 158: 343-359. PMID: 11797055, DOI: 10.1007/s002130100917.Peer-Reviewed Original ResearchConceptsDrug abuseSubstance abuseMost major theoriesHuman laboratory studiesField of addictionDrug seekingDrug useTreatment developmentMajor theoriesAbuse altersStress exposureVulnerable individualsHuman researchAbuseAddictsEmpirical evidencePreclinical evidenceClinical observationsRelapseAnimal studiesPreclinical researchSeekingGreater understandingAddictionResearch