2024
Memory-related brain potentials for visual objects in early AD show impairment and compensatory mechanisms
Xia J, Kutas M, Salmon D, Stoermann A, Rigatuso S, Farias S, Edland S, Brewer J, Olichney J. Memory-related brain potentials for visual objects in early AD show impairment and compensatory mechanisms. Cerebral Cortex 2024, 34: bhae398. PMID: 39390709, DOI: 10.1093/cercor/bhae398.Peer-Reviewed Original ResearchConceptsEvent-related brain potentialsAmnestic mild cognitive impairmentHippocampal occupancyBrain potentialsMemory abilityNegative ERP effectExecutive function abilitiesVisual memory abilityImpaired episodic memoryVerbal memory abilitiesAlzheimer's diseaseInvestigate neural mechanismsObject recognition taskVisual object recognitionVisual object recognition taskCognitively unimpaired participantsMild cognitive impairmentERP effectsNeuropsychological measuresExecutive functionEpisodic memoryHippocampal functionCompensatory mechanismsVisual memoryNeural mechanisms
2023
CSF tau markers are associated with fine memory discrimination in older adults with amnestic MCI in the EXERT trial
Fenton L, Aslanyan V, Jacobs D, Salmon D, Brewer J, Rissman R, Feldman H, Shadyab A, LaCroix A, Baker L, Pa J. CSF tau markers are associated with fine memory discrimination in older adults with amnestic MCI in the EXERT trial. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.080157.Peer-Reviewed Original ResearchAmnestic mild cognitive impairmentMemory discriminationOlder adultsMemory testLogical memoryHippocampal volumeAuditory Verbal Learning TestLogical memory testVerbal Learning TestBehavioral pattern separationVerbal memory testsMedial temporal lobeLarger hippocampal volumesMemory measuresList learningStory recallLearning TestObject taskMemory assessmentCognitive performanceMild cognitive impairmentPattern separationCognitive AssessmentStructural brain imagesTemporal lobe