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  • Suspect cells' 'neighbor' implicated in colorectal cancer

    Cancer researchers have zeroed in on a tightly sequestered group of stem cells within the intestine as suspects in the development of colon cancer but have been unable to explain exactly how genetic mutations within those stem cells can cause tumors of the digestive track.

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  • How T Cells Make Sure They Have Quiet Time

    All cells, like all people, need “quiet” time to function properly, and this is particularly true of T cells, one of the immune system’s main weapons. They must be ready for activation at all times, and primed to divide more rapidly than almost any cell in the body.

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  • Humanized Mice Lead to Breakthroughs in Blood Cancers

    Humanized mice created at Yale are opening new avenues of research into cancers caused by disorders in the production of blood, such as acute myelogenous leukemia (AML) and myelodysplastic syndromes (MDS). Until recently, such research was hindered because human blood stem cells are difficult to grow in cell cultures or to engraft in mice.

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  • Mechanical forces impact immune response in the lungs

    Mechanical forces impact immune response in the lungs By Ziba Kashef August 21, 2019 Share this with Facebook Share this with Twitter Share this with LinkedIn Share this with Email Print this 3d rendered medically accurate illustration of a mans lung (© When the body is fending off an infection, there are changes in temperature, pH balance, and metabolism. Yale researchers wondered if yet other factors might come into play, and in a recent study, confirmed that mechanical forces also influence the immune response.

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  • Yale scientists study genes misidentified as ‘non-protein coding’

    The human genome contains regions that “code” for proteins, which means they have instructions to make protein molecules with specific functions in the body. But Yale researchers have discovered several protein-coding genes that were misidentified as non-protein-coding, and one in particular that plays a key role in the immune system.

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