Anh Phu
About
Research
Publications
Featured Publications
ApoE expression in macrophages communicates immunometabolic signaling that controls hyperlipidemia-driven hematopoiesis & inflammation via extracellular vesicles.
Phu TA, Ng M, Vu NK, Gao AS, Raffai RL. ApoE expression in macrophages communicates immunometabolic signaling that controls hyperlipidemia-driven hematopoiesis & inflammation via extracellular vesicles. J Extracell Vesicles 2023, 12: e12345. PMID: 37593979, DOI: 10.1002/jev2.12345.Peer-Reviewed Original ResearchIL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity.
Phu TA, Ng M, Vu NK, Bouchareychas L, Raffai RL. IL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity. Molecular Therapy : The Journal Of The American Society Of Gene Therapy 2022, 30: 2274-2297. PMID: 35292359, DOI: 10.1016/j.ymthe.2022.03.008.Peer-Reviewed Original ResearchApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia.
Phu TA, Vu NK, Ng M, Gao AS, Stoolman JS, Chandel NS, Raffai RL. ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia. Cell Rep 2023, 42: 113206. PMID: 37824329, DOI: 10.1016/j.celrep.2023.113206.Peer-Reviewed Original Research
2026
Association between Genetic Variants of Uncertain Significance in Thoracic Aortic Disease and Outcomes Following Aortic Surgery.
Dankwa S, Phu TA, Erez E, Hameed I, Higaki ARA, Wang K, Khosla P, Ahmad D, Cupo M, Jallow M, Lee C, Lei Y, Talapaneni S, Ofori KA, Darby F, Shobayo TO, Verma S, Asmelash S, Naidoo T, Assi R, Vallabhajosyula P. Association between Genetic Variants of Uncertain Significance in Thoracic Aortic Disease and Outcomes Following Aortic Surgery. Ann Thorac Surg 2026 PMID: 42722264, DOI: 10.1016/j.athoracsur.2026.08.025.Peer-Reviewed Original ResearchM2 macrophage exosomes reverse heart failure post-myocardial infarction by suppressing type 1 interferon signaling in myeloid cells.
Ng M, Gao AS, Phu TA, Vu NK, Raffai RL. M2 macrophage exosomes reverse heart failure post-myocardial infarction by suppressing type 1 interferon signaling in myeloid cells. Mol Ther 2026, 34: 494-510. PMID: 41047630, DOI: 10.1016/j.ymthe.2025.10.010.Peer-Reviewed Original Research
2024
Label-free single-vesicle based surface enhanced Raman spectroscopy: A robust approach for investigating the biomolecular composition of small extracellular vesicles.
Liu Z, Ng M, Srivastava S, Li T, Liu J, Phu TA, Mateescu B, Wang YT, Tsai CF, Liu T, Raffai RL, Xie YH. Label-free single-vesicle based surface enhanced Raman spectroscopy: A robust approach for investigating the biomolecular composition of small extracellular vesicles. PLoS One 2024, 19: e0305418. PMID: 38889139, DOI: 10.1371/journal.pone.0305418.Peer-Reviewed Original Research
2023
Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes.
Liu M, Ng M, Phu T, Bouchareychas L, Feeley BT, Kim HT, Raffai RL, Liu X. Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes. Stem Cell Res Ther 2023, 14: 321. PMID: 37936229, DOI: 10.1186/s13287-023-03555-6.Peer-Reviewed Original ResearchExomap1 mouse: a transgenic model for in vivo studies of exosome biology.
Fordjour FK, Abuelreich S, Hong X, Chatterjee E, Lallai V, Ng M, Saftics A, Deng F, Carnel-Amar N, Wakimoto H, Shimizu K, Bautista M, Phu TA, Vu NK, Geiger PC, Raffai RL, Fowler CD, Das S, Christenson LK, Jovanovic-Talisman T, Gould SJ. Exomap1 mouse: a transgenic model for in vivo studies of exosome biology. BioRxiv 2023 PMID: 37398219, DOI: 10.1101/2023.05.29.542707.Peer-Reviewed Original ResearchPatients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes.
Lopez JL, Ramirez JL, Phu TA, Duong P, Bouchareychas L, Kuhrau CR, Lin PY, Eckalbar WL, Barczak AJ, Rudolph JD, Maliskova L, Conte MS, Vartanian SM, Raffai RL, Oskowitz AZ. Patients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes. PLoS One 2023, 18: e0281371. PMID: 36787323, DOI: 10.1371/journal.pone.0281371.Peer-Reviewed Original ResearchExomap1 mouse: A transgenic model for in vivo studies of exosome biology
Fordjour FK, Abuelreich S, Hong X, Chatterjee E, Lallai V, Ng M, Saftics A, Deng F, Carnel-Amar N, Wakimoto H, Shimizu K, Bautista M, Phu TA, Vu NK, Geiger PC, Raffai RL, Fowler CD, Das S, Christenson LK, Jovanovic-Talisman T, Gould SJ. Exomap1 mouse: a transgenic model for in vivo studies of exosome biology. Extracellular Vesicle 2023 , DOI: https://doi.org/10.1016/j.vesic.2023.100030.Peer-Reviewed Original Research