2022
Kappa opioid receptor antagonism protects working memory performance from mild stress exposure in Rhesus macaques
Wallace T, Martin W, Arnsten A. Kappa opioid receptor antagonism protects working memory performance from mild stress exposure in Rhesus macaques. Neurobiology Of Stress 2022, 21: 100493. PMID: 36532373, PMCID: PMC9755019, DOI: 10.1016/j.ynstr.2022.100493.Peer-Reviewed Original ResearchKappa-opioid receptorsKOR systemKappa opioid receptor antagonismNeurobehavioral disordersStress exposureSelective KOR antagonistOpioid receptor antagonismClinical evidence pointsBenzodiazepine inverse agonistStress-induced dysfunctionMild stress exposureKOR antagonistsReceptor antagonismMesocortical pathwayOpioid receptorsTherapeutic benefitKOR activityInverse agonistKOR expressionReceptor systemRhesus macaquesMild stress responseBrain networksEvidence pointsFunctional influence
2014
Catecholamine influences on prefrontal cortex circuits and function
Arnsten A, Berridge C. Catecholamine influences on prefrontal cortex circuits and function. 2014, 161-173. DOI: 10.1017/cbo9781139035491.015.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderHyperactivity disorderManagement of ADHDDiagnosis of ADHDChronic neurobehavioral disorderPrefrontal cortex circuitCatecholamine influenceCortex circuitTreatment modalitiesPsychiatric illnessNeurobehavioral disordersClinical optionBipolar disorderSocial workersDisordersRecent researchDiagnosisAdultsChildrenDevelopmental processesDistractibilityImpulsivityPsychologistsComorbiditiesWorld-renowned experts