Statistical assessment of biomarker replicability using MAJAR method
Xie Y, Zhai S, Jiang W, Zhao H, Mehrotra D, Shen J. Statistical assessment of biomarker replicability using MAJAR method. Statistical Methods In Medical Research 2023, 32: 1961-1972. PMID: 37519295, DOI: 10.1177/09622802231188519.Peer-Reviewed Original ResearchConceptsBayesian false discovery rateDifferent data generation processesNovel statistical frameworkExtensive simulation studyExpectation-maximization algorithmStatistical frameworkComputational efficiencyGWAS summary statistics dataSimulation studyData generation processStatistical assessmentSimulation resultsStatistical powerFalse discovery rateResponse predictionSummary statistics dataDiscovery rateSample sizeLimited powerOutliersAlgorithmGeneration processRobustnessPowerSmall sample size
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