Yale/NIDA Neuroproteomics Center Pilot Project Grants
| # | Year | Principal Investigator | Title | University | Project Title |
|---|---|---|---|---|---|
| 67 | 2024 | Mary Wang (with David Muddiman & Investigator Drew Kiraly) | Graduate Student | North Carolina State U. and Wake Forest U. | Evaluating the Relationship Between Short-Chain Fatty Acids and Related Metabolites in a Cocaine-treated Mouse Model of Substance Use Disorder by IR-MALDESI MS Imaging |
| 66 | 2024 | Tara Thompson-Felix (with Kieran O'Donnell) | Postdoctoral Associate | Yale U. | Fetal Neuroproteomic Landscape Associated with In-Utero Opioid Exposure |
| 65 | 2024 | Arnab Sengupta (with Mohini Ranganathan) | Postdoctoral Associate | Yale U. | Characterization of Proteomic Markers of Synaptic Dysfunction in Cannabis Use Disorder During Cannabis Exposure and After Abstinence, Using Plasma Derived Neuronal Extracellular Vesicles |
| 64 | 2024 | Philipp Mews | Assistant Professor | Boston U. | Epigenetic Imprints of Cocaine: Histone PTMs, Chromatin Changes, and the Link to Bipolar Disorder |
| 63 | 2024 | Bryan Killinger | Assistant Professor | Rush U.Medical Center | Mapping Addiction Signaling in the Striatum of Self-administering Mice |
| 62 | 2024 | Cheng Jiang (with Christopher Pittenger) | Associate Research Scientist | Yale U. | Stress-induced Sex- and Cell Type-specific Proteomic Changes in the Striatum: Impact on Substance Abuse |
| 61 | 2024 | Kelsea Gildawie | Assistant Professor | Simmons U. | Prenatal Exposure to Medications for Opioid Use Disorder: Sex-Dependent Effects on Adolescent Prefrontal Cortex Development |
| 60 | 2023 | Yifei Cai (with Jamie Grutzendler) | Associate Research Scientist | Yale U. | Cell-type-specific Proteomics in Human Brains Using Immunopanning and Antibody-based Proximity Labeling |
| 59 | 2023 | Soren Emerson (with Erin Calipari) | NIDA Prodoctoral Fellow | Vanderbilt U. | Investigating the Cell Type-Specific Recruitment of the SAGA Complex in Cocaine Use Disorder |
| 58 | 2023 | Nadine Kabbani | Associate Professor | George Mason U. | Sex-specific Proteomic Adaptations in Microglia in Response to Nicotine Treatment and Withdrawal |
| 57 | 2023 | Angela Redmond | Assistant Research Professor | Marshall U. | Understanding Biased CB1R Signaling Through Phospho-Proteomics |
| 56 | 2023 | Alexandra Fall (with Marco Venniro) | PhD Student | U. Maryland | Investigating the Central Amygdala Neuronal Proteome Mediating the Protective Effect of Social Reward on Incubation of Heroin Craving |
| 55 | 2023 | Isabel Gameiro-Ros (with Paul Slesinger) | Postdoctoral Fellow | Icahn School of Medicine at Mount Sinai | Proteomic Profiling of Glutamate Neurotransmission Alterations with Chronic THC and/or Ethanol Exposure in the Context of Addiction in iPSC-derived Human Excitatory Neurons |
| 54 | 2022 | Vena Martinez | Postdoctoral Associate | Yale U. | Targeted Discovery and Characterization of Opioid Use Disorder (OUD) Causal Genes Through Proteomic Analysis of Human Brain Regions |
| 53 | 2022 | Ken Loh | Assistant Professor | Yale U. | Developing new enzymatic scaffolds for proximity labeling brain regions |
| 52 | 2022 | Sarah Jefferson | Psychiatry Resident | Yale U. | Short- and Long-term Proteomic Changes in Dendritic Spines Induced by Psychedelic Compounds with Therapeutic Applications |
| 51 | 2022 | Zuhair Abdulla (with Marina Picciotto) | Postdoctoral Associate | Yale U. | Synaptoproteomic Correlates of Stress-induced Acetylcholine Release in mPFC: Mechanistic Evaluation of Depression/addiction Co-morbidity |
| 50 | 2022 | Xiaofan Li (with Paul Slesinger) | Instructor | Icahn School of Medicine at Mount Sinai | Mapping Methamphetamine-induced Changes in the GIRK Channel Interaction Proteome |
| 49 | 2022 | Candice Paulsen | Assistant Professor | Yale U. | Proteomic Analysis of Protein Partners that Govern TRPA1 Trafficking and Functionality |
| 48 | 2021 | Ethan Anderson (with Christopher Cowan) | Research Assistant Professor | Medical U. South Carolina | Phospholipase Cgamma1 in the Nucleus Accumbens Reduces Heroin-Seeking: Effects on Synaptic Phospholipids and the Synaptoproteome |
| 47 | 2021 | Anissa Bara (with Yasmin Hurd) | Postdoctoral Fellow | Icahn School of Medicine at Mount Sinai | Placenta and Neurodevelopmental Effects of in utero Cannabis Exposure |
| 46 | 2021 | Cheng Jiang (with Christopher Pittenger) | Postdoctoral Associate | Yale U. | Stress-induced Sex- and Cell Type-specific Proteomic Changes in the Striatum: Impact on Substance Abuse |
| 45 | 2021 | Pradeep Kurup (with James Bibb) | Instructor | U. Alabama | Proteomic Characterization of ?OR and Cdk5 Signaling Pathway in Rodent Nucleus Accumbens: Implications in Cocaine Addiction |
| 44 | 2021 | Yun Young Yim (with Eric Nestler) | Postdoctoral Fellow | Icahn School of Medicine at Mount Sinai | Cell-type-specific Proteomic Profiling of Synaptosomes During Early and Extended Withdrawal from Self-administered Cocaine |
| 43 | 2020 | Suhas Ganesh (with Mohini Ranganathan) | Postdoctoral Associate | Yale U. | Capturing Altered Brain Proteomic Signaling in Young Onset Cannabis Use Disorder in the Periphery Leveraging Label Free Proteomic Analysis of Neuron Derived Circulating Exosomes |
| 42 | 2020 | Rebecca Hofford | Postdoctoral Associate | Icahn School of Medicine at Mount Sinai | Investigation of the Adolescent Gut Microbiome as a Unique Driver of Protein Expression in Medial Prefrontal Cortex After Opioid Exposure |
| 41 | 2020 | Valeria Lallai | Postdoctoral Associate | U. Cal. Irvine | Proteomics of THC-mediated Changes in Extracellular Vesicle Signaling |
| 40 | 2020 | Anna Moszczynska | Associate Professor | Wayne State U. | Investigating Proteins Mediating Ubiquitin-Protein Ligase Parkin-Induced Attenuation of Methamphetamine Relapse |
| 39 | 2021 | Stephanie Puig (with Ryan Logan) | Senior Research Scientist | Boston U. | Identifying The PDGFRß Signaling Pathways That Mediate Opioid Tolerance |
| 38 | 2020 | Yotam Sagi | Senior Research Associate | Rockefeller U. | Protein Analysis from Organelles and Cellular Compartments of Neuronal Populations |
| 37 | 2021 | Summer Thompson (with Jane Taylor) | Postdoctoral Associate | Yale U. | Profiling Microbial Metabolites To Elucidate The Relationship Between SCFAs, Intestinal Permeability, and Alcohol |
| 36 | 2019 | Kristen Brennand | Associate Professor | Icahn School of Medicine at Mount Sinai | Impact of NRXN1a Alternative Splicing Changes on Synaptic Composition |
| 35 | 2019 | Yifei Cai (with Jaime Grutzendler) | Postdoctoral Associate | Yale U. | Proteomic Screening of Neuronal and Glial Subcellular Compartments Isolated by Proximity Labeling and FACS in Fixed and Fresh Brain Samples |
| 34 | 2019 | Mohammad Shahid Mansuri (with Angus Nairn) | Postdoctoral Associate | Yale U. | Ultra-deep Brain Tyrosine Phosphoproteomic Profiling by SH2-Superbinder |
| 33 | 2019 | James Quinn (with Steve Arnold) | Postdoctoral Fellow | Mass. General Hospital | Analyzing the Role of Neuropeptides in the Neurobiology and Physiology of Addiction |
| | | | | | |
| 32 | 2018 | Caleb Browne (with Eric Nestler) | Postdoctoral Fellow | Icahn School of Medicine at Mount Sinai | Proteomic Profiling of NAc Synaptosomes During Early and Extended Withdrawal from Self-administered Cocaine |
| 31 | 2018 | Ayanabha Chakraborti (with James Bibb) | Senior Research Associate | U. Alabama at Birmingham | Profiling the Nucleus Accumbens Proteome in an Experimental Model of Inflammatory Bowel Disease |
| 30 | 2018 | Tina Franklin (with Ron Duman) | Postdoctoral Associate | Yale U. | Stress-induced Dysregulation in Microglial HMGB1 Signaling |
| 29 | 2018 | Stephanie Groman (with Jane Taylor) | Associate Research Scientist | Yale U. | A "Targeted" Approach to Identify the Proteins Underlying the Biobehavioral Mechanisms of Addiction |
| 28 | 2018 | Angela Lee (with Marina Picciotto) | MD/PhD Student | Yale U. | Sex Differences in Nicotine-induced Changes of the Mouse Brain Proteome |
| 27 | 2017 | L. Devi and D. Schechtman | Professor and Assoc. Professor | Icahn School of Medicine at Mount Sinai and U. Sao Paulo, Brazil | Identification of Protein Kinase C Targets Leading to Opioid Tolerance |
| 26 | 2017 | D. Kiraly | Assistant Professor | Icahn School of Medicine at Mount Sinai | Characterization of Proteomic Changes in the Nucleus Accumbens in Response to Chronic Granulocyte-colony Stimulating Factor and Cocaine |
| 25 | 2017 | M. Girgenti | Postdoctoral Associate | Yale U. | Post Mortem Proteomic Characterization of Human Subgenual Prefrontal Cortex in Tobacco Abuse and PTSD |
| 24 | 2017 | M. Wolf and A. Li | Professor and Postdoctoral Associate | Chicago Medical School and Behavioral Neuroscience Branch, NIDA | Projection-specific Proteomics in Striatum and Its Glutamatergic Afferents in Incubation of Craving to Psychostimulants (Cocaine and Methamphetamine) |
| 23 | 2016 | T. Cijsouw (with T. Biederer) | Postdoctoral Scholar | Tufts U. | Mapping the Proteome of the Synaptic cleft Through Peroxidase-Based Reporter Proteins |
| 22 | 2016 | R. Logan | Assistant Professor | U. Pittsburgh | Identifying Circadian Regulated Proteins in Specific Cell Types of the Nucleus Accumbens involved in Cocaine Reward |
| 21 | 2016 | M. Miller (with M. Picciotto) | Postdoctoral Associate | Yale U. | A Systematic Evaluation of High-Affinity a4ß2 Nicotinic Acetylcholine Receptor Phosphorylation |
| 20 | 2017 | M. Monsey (with J. Taylor) | Postdoctoral Associate | Yale U. | Profiling the neuronal proteome of the lateral amygdala following cocaine-cue memory retrieval and systemic garcinol administration |
| 19 | 2017 | R. Taugher | Postdoctoral Fellow | U. Iowa | Role of ASIC1A in regulating the NAc proteome in both the drug naïve and cocaine withdrawn states |
| 18 | 2017 | E. Yan | Professor | Yale U. | Role of dimerization in modulating sensitivity and dynamic range of ligand sensing in family CG protein coupled receptors |
| 17 | 2015 | B. Carlyle (with A. Nairn) | Postdoctoral Associate | Yale U. | Assessing Proteomic Differences Between the Two Types of Major Cell Types of the Striatum |
| 16 | 2015 | A. Koleske | Professor | Yale U. | Mechanisms of Cocaine-Induced Dendritic Spine Refinement and Plasticity |
| 15 | 2015 | J. Uys (with P. Kalivas) | Assistant Professor | Medical U. South Carolina | Quantitative Proteomic Analysis of S-Glutathionylated Proteins after Cocaine-Induced Reinstatement |
| 14 | 2015 | J. Xu (with P. Lombroso) | Assoc. Res. Sci. | Yale U. | Post-Translational Modification of STEP61 by BDNF Signalling: Implications in Drug Abuse |
| 13 | 2012 | R. Kitchen (with A. Nairn) | Postdoctoral Associate | Yale U. | Toward Improved Label-free Quantification of MS/MS Spectra Using Predicted Proteomes |
| 12 | 2011 | S. Chandra | Assistant Professor | Yale U. | Phosphoinositides, Synaptic Signalling, Drug Addiction, and Neurodegeneration |
| 11 | 2011 | M. Koelle | Associate Professor | Yale U. | Proteomic Analysis of Lysine Acetylation of the Neural G Protein Gao and Its Role in Serotonin Signaling |
| 10 | 2011 | T. McClure-Begley (with M. Picciotto) | Postdoctoral Fellow | Yale U. | Defining the nAChR Interactome |
| 9 | 2011 | S. Sathyanesan | Assistant Professor | Yale U. | Development of Cerebrospinal Fluid Markers for Neuropsychiactric Disorders |
| 8 | 2010 | J. Bibb | Associate Professor | U. Texas Southwestern Medical Center | Phosphoprotein Analysis of the Effects of Cocaine on NMDA Receptor Regulation |
| 7 | 2010 | J. Rinehart | Assistant Professor | Yale U. | Global MRM Atlas of the Human Kinome |
| 6 | 2010 | A.J. Robison (with E. Nestler) | Postdoctoral Fellow | Icahn School of Medicine at Mount Sinai | Neuronal Subtype-Specific Effects of the Transcription Factor delta FosB on Synaptic Physiology |
| 5 | 2010 | M. Torregrossa (with J. Taylor) | Assoc. Res. Sci. | Yale U. | Identification of Proteins that are Differentially Activated by Drug Cue memory Extinction and Reconsolidation in the Amygdala and Nucleus Accumbens Using Phosphoproteomics |
| 4 | 2009 | T. Biederer | Associate Professor | Yale U. | Identification and Analysis of Protein Complexes Mediating Synapse Formation |
| 3 | 2009 | S. Chandra | Assistant Professor | Yale U. | Neuronal Substrates Required for Synapse Maintenance |
| 2 | 2009 | M. Morabito | Assistant Professor | U. Mass. | Cdk5-Dependent Post-translational Modifications of PSD-95 |
| 1 | 2009 | S. Sathyanesan | Assistant Professor | Yale U. | A Proteomics and Genomics Characterization of the Choroid Plexus: Protein and Gene Regulation by Psychotropic Drugs |