Hongyan Hao
Postdoctoral Associate in NeuroscienceAbout
Research
Publications
2026
Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin
Li D, Wang X, Hao H, Eden J, Hu B, Walsh E, Parson M, Hamill S, Li Y, Chen G, Burke J, De Camilli P, Reinisch K. Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin. Molecular Cell 2026, 86: 2843-2857.e10. PMID: 42413490, PMCID: PMC13430412, DOI: 10.1016/j.molcel.2026.06.028.Peer-Reviewed Original Research
2025
Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo
Ding X, Hao H, Elnatan D, Alinaya P, Kalra S, Kaur A, Kumari S, Holt L, Luxton G, Starr D. Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo. Science Advances 2025, 11: eadx0952. PMID: 40929259, PMCID: PMC12422203, DOI: 10.1126/sciadv.adx0952.Peer-Reviewed Original Research
2024
Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport
Wu Y, Ding C, Sharif B, Weinreb A, Swaim G, Hao H, Yogev S, Watanabe S, Hammarlund M. Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport. Journal Of Cell Biology 2024, 223: e202305105. PMID: 38470363, PMCID: PMC10932739, DOI: 10.1083/jcb.202305105.Peer-Reviewed Original Research
2022
The ANC-1 (Nesprin-1/2) organelle-anchoring protein functions through mitochondria to polarize axon growth in response to SLT-1
Fischer N, Friedman V, Martinez-Reyes M, Hao H, Chowdhury T, Starr D, Quinn C. The ANC-1 (Nesprin-1/2) organelle-anchoring protein functions through mitochondria to polarize axon growth in response to SLT-1. PLOS Genetics 2022, 18: e1010521. PMID: 36409768, PMCID: PMC9721489, DOI: 10.1371/journal.pgen.1010521.Peer-Reviewed Original Research
2019
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis
Ji Y, Hao H, Reynolds K, McMahon M, Zhou C. Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. Cells 2019, 8: 1173. PMID: 31569501, PMCID: PMC6829301, DOI: 10.3390/cells8101173.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRole of KASH domain lengths in the regulation of LINC complexes
Jahed Z, Hao H, Thakkar V, Vu U, Valdez V, Rathish A, Tolentino C, Kim S, Fadavi D, Starr D, Mofrad M. Role of KASH domain lengths in the regulation of LINC complexes. Molecular Biology Of The Cell 2019, 30: 2076-2086. PMID: 30995155, PMCID: PMC6727767, DOI: 10.1091/mbc.e19-02-0079.Peer-Reviewed Original ResearchSUN/KASH interactions facilitate force transmission across the nuclear envelope
Hao H, Starr D. SUN/KASH interactions facilitate force transmission across the nuclear envelope. Nucleus 2019, 10: 73-80. PMID: 30888237, PMCID: PMC6527376, DOI: 10.1080/19491034.2019.1595313.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning
Cain N, Jahed Z, Schoenhofen A, Valdez V, Elkin B, Hao H, Harris N, Herrera L, Woolums B, Mofrad M, Luxton G, Starr D. Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning. Current Biology 2018, 28: 3086-3097.e4. PMID: 30245107, PMCID: PMC6219386, DOI: 10.1016/j.cub.2018.08.001.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsBiological TransportCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsCell NucleusCytoskeletonIntracellular Signaling Peptides and ProteinsMembrane ProteinsMiceMicrotubulesNIH 3T3 CellsNuclear EnvelopeNuclear MatrixNuclear ProteinsProtein Structure, TertiaryProtein Transport
2015
Nuclear‐localized AtHSPR links abscisic acid‐dependent salt tolerance and antioxidant defense in Arabidopsis
Yang T, Zhang L, Hao H, Zhang P, Zhu H, Cheng W, Wang Y, Wang X, Wang C. Nuclear‐localized AtHSPR links abscisic acid‐dependent salt tolerance and antioxidant defense in Arabidopsis. The Plant Journal 2015, 84: 1274-1294. PMID: 26603028, DOI: 10.1111/tpj.13080.Peer-Reviewed Original Research
2014
Cloning and characterization of a novel Athspr promoter specifically active in vascular tissue
Zhang L, Yang T, Li X, Hao H, Xu S, Cheng W, Sun Y, Wang C. Cloning and characterization of a novel Athspr promoter specifically active in vascular tissue. Plant Physiology And Biochemistry 2014, 78: 88-96. PMID: 24675528, DOI: 10.1016/j.plaphy.2014.02.019.Peer-Reviewed Original ResearchArabidopsisArabidopsis ProteinsBase SequenceCambiumCloning, MolecularDNA, PlantGene Expression Regulation, PlantGenes, PlantGlucuronidaseGreen Fluorescent ProteinsHistocytochemistryMicroscopy, FluorescenceMolecular Sequence DataMutationPlant RootsPlant Vascular BundlePlants, Genetically ModifiedPromoter Regions, GeneticRegulatory Sequences, Nucleic AcidSeedlings
News
News
- July 29, 2026
New Insights into Proteins Linked to Neurodegeneration
- April 09, 2026
Meet our Speakers: Dr. Emmanuelle Bayer, Research Director, Laboratory of Membrane Biogenesis, CNRS-Bordeaux University
- May 14, 2024
#TraineeTuesday: Hongyan Hao, PhD
- May 03, 2024
Hao, Chen, and Bhaskar Honored With 2024 Kavli Postdoctoral Fellowship
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100 College Street
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Fl 3rd
New Haven, CT 06510