2023
Pragmatic evaluation of events and benefits of lipid lowering in older adults (PREVENTABLE): Trial design and rationale
Joseph J, Pajewski N, Dolor R, Sellers M, Perdue L, Peeples S, Henrie A, Woolard N, Jones W, Benziger C, Orkaby A, Mixon A, VanWormer J, Shapiro M, Kistler C, Polonsky T, Chatterjee R, Chamberlain A, Forman D, Knowlton K, Gill T, Newby L, Hammill B, Cicek M, Williams N, Decker J, Ou J, Rubinstein J, Choudhary G, Gazmuri R, Schmader K, Roumie C, Vaughan C, Effron M, Cooper‐DeHoff R, Supiano M, Shah R, Whittle J, Hernandez A, Ambrosius W, Williamson J, Alexander K, Group P. Pragmatic evaluation of events and benefits of lipid lowering in older adults (PREVENTABLE): Trial design and rationale. Journal Of The American Geriatrics Society 2023, 71: 1701-1713. PMID: 37082807, PMCID: PMC10258159, DOI: 10.1111/jgs.18312.Peer-Reviewed Original ResearchConceptsOlder adultsHigh-intensity statin therapyRandomized pragmatic clinical trialCognitive testingBenefits of lipidInitiation of statinsBenefits of statinsNational Death Index searchEffect of statinsPragmatic clinical trialsCommunity-dwelling adultsMild cognitive impairmentLow participant burdenBaseline cognitive testingElectronic health recordsCardiovascular deathCardiovascular eventsCoronary revascularizationLipid panelStatin therapyStatin useUnstable anginaHeart failurePrimary outcomeMyocardial infarction
1996
Impairments in Physical Performance and Cognitive Status as Predisposing Factors for Functional Dependence Among Nondisabled Older Persons
Gill T, Williams C, Richardson E, Tinetti M. Impairments in Physical Performance and Cognitive Status as Predisposing Factors for Functional Dependence Among Nondisabled Older Persons. The Journals Of Gerontology Series A 1996, 51A: m283-m288. PMID: 8914500, DOI: 10.1093/gerona/51a.6.m283.Peer-Reviewed Original ResearchConceptsCognitive statusPhysical performanceOlder personsCommunity-living older adultsSlow functional declineWorse physical performanceCommunity-living adultsComplete outcome dataChronic conditionsPredisposing factorsFunctional declineDaily livingOutcome dataCognitive testingOlder adultsImpairmentRiskProbability sampleSubjectsStatusAdultsYearsComprehensive assessmentSimilar resultsFollow