2023
Foundation models for generalist medical artificial intelligence
Moor M, Banerjee O, Abad Z, Krumholz H, Leskovec J, Topol E, Rajpurkar P. Foundation models for generalist medical artificial intelligence. Nature 2023, 616: 259-265. PMID: 37045921, DOI: 10.1038/s41586-023-05881-4.Peer-Reviewed Original ResearchConceptsMedical AILarge medical datasetsMedical artificial intelligenceArtificial intelligence modelsImage annotationMedical datasetsArtificial intelligenceElectronic health recordsAI devicesIntelligence modelsTraining datasetDiverse datasetsExpressive outputHealth recordsRapid developmentDatasetFree-text explanationsMedical modalitiesNew paradigmMedical textsAITechnical capabilitiesDiverse setNewfound capabilitiesCapability
2020
Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND)
Schuemie MJ, Ryan PB, Pratt N, Chen R, You SC, Krumholz HM, Madigan D, Hripcsak G, Suchard MA. Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND). Journal Of The American Medical Informatics Association 2020, 27: 1331-1337. PMID: 32909033, PMCID: PMC7481029, DOI: 10.1093/jamia/ocaa103.Peer-Reviewed Original ResearchConceptsNetwork of databasesLarge-scale Evidence GenerationObservational Health Data SciencesObservational health care databasesHealth Data SciencesHealth care dataElectronic health recordsData sciencePublication biasPatient-level informationGeneric overviewHealth recordsMethods addressAforementioned concernsHealth care databasesAnalytic codeNetworkNew paradigmSuch dataHackingEvidence generationDissemination of evidenceHypertension treatmentResidual confoundingAdministrative claims