2024
Impact of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Chronic Kidney Disease: A Middle East and Africa Perspective
Elkeraie A, Al-Ghamdi S, Abu-Alfa A, Alotaibi T, AlSaedi A, AlSuwaida A, Arici M, Ecder T, Ghnaimat M, Hafez M, Hassan M, Sqalli T. Impact of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Chronic Kidney Disease: A Middle East and Africa Perspective. International Journal Of Nephrology And Renovascular Disease 2024, 17: 1-16. PMID: 38196830, PMCID: PMC10771977, DOI: 10.2147/ijnrd.s430532.Peer-Reviewed Original ResearchChronic kidney diseaseSodium-glucose cotransporter 2 inhibitorsCotransporter 2 inhibitorsDiabetes mellitusKidney diseaseType 2 diabetes mellitusMajor public health concernAldosterone system inhibitorsBetter clinical outcomesCause of deathPublic health concernNephrology referralCKD managementClinical outcomesSystem inhibitorsCardioprotective propertiesEarly initiationTreatment pathwaysConsensus recommendationsHigh riskPatientsBetter careHealth concernEarly detectionHypertension
1997
Sodium-hydrogen exchange isoform expression in blood cells: implications for studies in diabetes mellitus
Rutherford P, Pizzonia J, Abu-Alfa A, Biemesderfer D, Reilly R, Aronson P. Sodium-hydrogen exchange isoform expression in blood cells: implications for studies in diabetes mellitus. Experimental And Clinical Endocrinology & Diabetes 1997, 105: 13-16. PMID: 9288535, DOI: 10.1055/s-0029-1211787.Peer-Reviewed Original ResearchConceptsPeripheral blood cellsPeripheral blood cell preparationsDiabetes mellitusBlood cell preparationsBlood cellsNHE activityPathophysiological roleNa-H exchange activityNHE-1Vascular smooth muscle cell proliferationNHE-3Smooth muscle cell proliferationProgressive renal impairmentNHE isoformsVascular smooth muscleDirect pathophysiological roleCell preparationsMuscle cell proliferationPlatelet membranesNa-H exchangeRenal proximal tubulesNHE isoforms 1Sodium-hydrogen exchangeRenal impairmentNondiabetic controls