2019
Self-reported antiretroviral therapy adherence and viral load in criminal justice-involved populations
Cunningham WE, Nance RM, Golin CE, Flynn P, Knight K, Beckwith CG, Kuo I, Spaulding A, Taxman FS, Altice F, Delaney JA, Crane HM, Springer SA. Self-reported antiretroviral therapy adherence and viral load in criminal justice-involved populations. BMC Infectious Diseases 2019, 19: 913. PMID: 31664910, PMCID: PMC6819597, DOI: 10.1186/s12879-019-4443-z.Peer-Reviewed Original ResearchConceptsViral loadART adherenceAdherence measuresSelf-reported antiretroviral therapy (ART) adherenceCriminal justice-involved populationsSelf-reported ART adherenceLogistic regressionSelf-reported health statusContinuum of HIVDetectable viral loadPlasma viral loadAIDS Research NetworkAntiretroviral therapy adherenceAssociation of adherenceHealth status levelsVisual analog scaleViral load dataMixed-effects logistic regressionMixed effects linear regressionEffects linear regressionJustice-involved populationsEffects logistic regressionVL outcomesCD4 countART dosesEvaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine
Ranjit YS, Azbel L, Krishnan A, Altice FL, Meyer JP. Evaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine. AIDS Care 2019, 31: 793-797. PMID: 30701981, PMCID: PMC6510603, DOI: 10.1080/09540121.2019.1573969.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiretroviral Therapy, Highly ActiveAzerbaijanCommunicable DiseasesComorbidityContinuity of Patient CareFemaleHealth Services AccessibilityHepatitis CHIV InfectionsHumansKyrgyzstanMaleMental DisordersMiddle AgedPrevalencePrisonersPrisonsSubstance-Related DisordersSurveys and QuestionnairesSyphilisUkraineConceptsAlcohol use disorderAntiretroviral therapyHIV preventionHIV riskHIV care continuumCells/μLHigh-risk groupComorbid substance useEffective HIV preventionGlobal HIV preventionHigh rateHepatitis CIncarcerated womenHIV testingHIV incidenceHIV prevalencePsychiatric comorbidityDrug injectionRepresentative sampleCare continuumRisk groupsPsychiatric disordersMost womenUse disordersTreatment interventions
2018
Adherence to Antiretroviral Therapy Among Incarcerated Persons with HIV: Associations with Methadone and Perceived Safety
Culbert GJ, Waluyo A, Wang M, Putri TA, Bazazi AR, Altice FL. Adherence to Antiretroviral Therapy Among Incarcerated Persons with HIV: Associations with Methadone and Perceived Safety. AIDS And Behavior 2018, 23: 2048-2058. PMID: 30465106, PMCID: PMC6698149, DOI: 10.1007/s10461-018-2344-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiretroviral Therapy, Highly ActiveCross-Sectional StudiesHIVHIV InfectionsHumansIndonesiaMaleMedication AdherenceMethadoneOdds RatioOpiate Substitution TreatmentPrisonersSubstance-Related DisordersConceptsAntiretroviral therapyART adherenceART utilizationMethadone utilizationHIV status disclosureHealth service satisfactionStatus disclosureMedical treatmentDrug dependencyPWHAdherenceMost participantsHIVMethadoneTherapyChance locusSafetyAdequate supportHigh levelsPerceived SafetyPersonal safety
2017
Predictors of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study
Loeliger KB, Altice FL, Desai MM, Ciarleglio MM, Gallagher C, Meyer JP. Predictors of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study. The Lancet HIV 2017, 5: e96-e106. PMID: 29191440, PMCID: PMC5807129, DOI: 10.1016/s2352-3018(17)30209-6.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveContinuity of Patient CareFemaleHIV InfectionsHumansMaleOutcome Assessment, Health CarePopulation SurveillancePrisonersPrisonsRetrospective StudiesTreatment OutcomeViral LoadConceptsHIV treatment outcomesHIV careViral suppressionTreatment outcomesPoor HIV treatment outcomesMore medical comorbiditiesPost-release linkagePredictors of linkageRetrospective cohort studyDetectable viral loadCase management servicesCase management dataTransitional case managementHealth care goalsAntiretroviral therapyMedical comorbiditiesCohort studyRetrospective cohortDays of releaseViral loadPharmacy databasePsychiatric comorbidityUS National InstitutesCase management needsHispanic ethnicity
2015
The Influence of Medication Attitudes on Utilization of Antiretroviral Therapy (ART) in Indonesian Prisons
Culbert GJ, Bazazi AR, Waluyo A, Murni A, Muchransyah AP, Iriyanti M, Finnahari, Polonsky M, Levy J, Altice FL. The Influence of Medication Attitudes on Utilization of Antiretroviral Therapy (ART) in Indonesian Prisons. AIDS And Behavior 2015, 20: 1026-1038. PMID: 26400080, PMCID: PMC4805506, DOI: 10.1007/s10461-015-1198-4.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART utilizationIndonesian prisonersMedication attitudesIndonesian prisonsHalf of participantsHIV medicationsHIV stigmaART efficacyMultivariate analysisEligibility guidelinesHIVAdverse effectsMixed-method studyTherapyART attitudesMale prisonersParticipantsMedicationsSocial marketingStructured surveyNegative attitudesCorrelates and Experiences of HIV Stigma in Prisoners Living With HIV in Indonesia: A Mixed-Method Analysis
Culbert GJ, Earnshaw VA, Wulanyani NM, Wegman MP, Waluyo A, Altice FL. Correlates and Experiences of HIV Stigma in Prisoners Living With HIV in Indonesia: A Mixed-Method Analysis. Journal Of The Association Of Nurses In AIDS Care 2015, 26: 743-757. PMID: 26304049, PMCID: PMC4600662, DOI: 10.1016/j.jana.2015.07.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveHIV InfectionsHumansIndonesiaInterviews as TopicMaleMiddle AgedPrincipal Component AnalysisPrisonersPrisonsPsychiatric Status Rating ScalesQualitative ResearchSelf DisclosureSexual PartnersSocial DiscriminationSocial StigmaSurveys and QuestionnairesTruth DisclosureConceptsHIV stigmaExperiences of stigmaDrug-related offensesMixed-methods analysisDepth interviewsSyndemic natureLargest prisonFamily membersPrisonersHIV statusIndonesiaDrug useStigmaIncarcerationCurrent incarcerationGroup of HIVMale HIVStigma SurveyHIV treatmentExperienceHIVPrisonOffensesPrevention goalsStigma levels
2012
Absence of Antiretroviral Therapy and Other Risk Factors for Morbidity and Mortality in Malaysian Compulsory Drug Detention and Rehabilitation Centers
Fu JJ, Bazazi AR, Altice FL, Mohamed MN, Kamarulzaman A. Absence of Antiretroviral Therapy and Other Risk Factors for Morbidity and Mortality in Malaysian Compulsory Drug Detention and Rehabilitation Centers. PLOS ONE 2012, 7: e44249. PMID: 23028508, PMCID: PMC3445567, DOI: 10.1371/journal.pone.0044249.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiretroviral Therapy, Highly ActiveHealth Services AccessibilityHIV InfectionsHumansMalaysiaMaleMorbidityRehabilitation CentersSubstance-Related DisordersConceptsCompulsory drug detentionAntiretroviral therapyRehabilitation centerMedical careUntreated medical conditionsOpioid substitution therapyUnmet health needsPercent of participantsActive tuberculosisEvidence-based drug policyOpioid dependenceSubstitution therapyRisk factorsClinical assessmentMedical conditionsHigh riskHIVDrug useHealth statusHealth needsSuicidal ideationTherapyMale detaineesMost participantsCareSurvival from XDR-TB Is Associated with Modifiable Clinical Characteristics in Rural South Africa
Shenoi SV, Brooks RP, Barbour R, Altice FL, Zelterman D, Moll AP, Master I, van der Merwe TL, Friedland GH. Survival from XDR-TB Is Associated with Modifiable Clinical Characteristics in Rural South Africa. PLOS ONE 2012, 7: e31786. PMID: 22412840, PMCID: PMC3295798, DOI: 10.1371/journal.pone.0031786.Peer-Reviewed Original ResearchConceptsXDR-TB patientsDrug-resistant tuberculosisRetrospective case-control studyXDR-TB casesCommunity-based hospitalCase-control studyGlobal public healthHIV coinfectionMicrobiological correlatesModifiable factorsAvailable interventionsRural South AfricaControl studyPatientsTuberculosisPublic healthSurvivorsSurvivalDaysHospitalMortality
2011
Medication Persistence of HIV-infected Drug Users on Directly Administered Antiretroviral Therapy
Ing EC, Bae JW, Maru DS, Altice FL. Medication Persistence of HIV-infected Drug Users on Directly Administered Antiretroviral Therapy. AIDS And Behavior 2011, 17: 113-121. PMID: 22105340, DOI: 10.1007/s10461-011-0082-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBehavior, AddictiveCD4 Lymphocyte CountConnecticutDirectly Observed TherapyDrug UsersFemaleHIV InfectionsHumansInterviews as TopicKaplan-Meier EstimateMaleMedication AdherenceProportional Hazards ModelsRandomized Controlled Trials as TopicRNA, ViralSeverity of Illness IndexSubstance Abuse, IntravenousTreatment OutcomeViral LoadConceptsDrug usersAntiretroviral therapyPatterns of medicationInjection drug useMedication-taking behaviorHigher depressive symptomsVirological outcomesMedication persistenceRegimen changeMore episodesDepressive symptomsHigher addiction severityDrug useSignificant associationConsecutive daysHIVAddiction severityMedicationsMEMS dataTherapyDaysEpisodesParticipantsRegimensDAARTComputer-Based Intervention in HIV Clinical Care Setting Improves Antiretroviral Adherence: The LifeWindows Project
Fisher JD, Amico KR, Fisher WA, Cornman DH, Shuper PA, Trayling C, Redding C, Barta W, Lemieux AF, Altice FL, Dieckhaus K, Friedland G, for the LifeWindows Team. Computer-Based Intervention in HIV Clinical Care Setting Improves Antiretroviral Adherence: The LifeWindows Project. AIDS And Behavior 2011, 15: 1635. PMID: 21452051, DOI: 10.1007/s10461-011-9926-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveComputersConnecticutFemaleHIV InfectionsHumansMaleMedication AdherenceMiddle AgedPatient Education as TopicSoftwareUser-Computer InterfaceViral LoadConceptsHIV clinical care settingsAdherence support interventionsClinical care sitesClinical care settingsHIV careCare visitsAntiretroviral adherenceControl armCare settingsCare sitesProtocol interventionTreat sampleProtocol sampleSupport interventionsComputer-based interventionsIntervention impactControl participantsInterventionAdherenceHIVPatientsCareHigh levelsClinicARVImproving Adherence to HIV Quality of Care Indicators in Persons With Opioid Dependence: The Role of Buprenorphine
Korthuis PT, Fiellin DA, Fu R, Lum PJ, Altice FL, Sohler N, Tozzi MJ, Asch SM, Botsko M, Fishl M, Flanigan TP, Boverman J, McCarty D. Improving Adherence to HIV Quality of Care Indicators in Persons With Opioid Dependence: The Role of Buprenorphine. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 56: s83-s90. PMID: 21317600, PMCID: PMC3066190, DOI: 10.1097/qai.0b013e31820bc9a5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBuprenorphineBuprenorphine, Naloxone Drug CombinationCohort StudiesFemaleGuideline AdherenceHIV InfectionsHumansMaleMiddle AgedMultivariate AnalysisNaloxoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPractice Guidelines as TopicQuality of Health CareConceptsBUP/NXHIV careOpioid dependenceHIV qualitySummary quality scoresCare indicatorsBuprenorphine/naloxone maintenance therapyHigh-quality HIV careOpioid-dependent HIVRole of buprenorphineObservational cohort studyOpioid-dependent patientsQuality scoresNondependent patientsHIV clinicMaintenance therapyCohort studyBuprenorphine treatmentClinical outcomesMultivariable analysisMedical recordsPatientsCareMonthsHIV
2010
A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization
Azar MM, Springer SA, Meyer JP, Altice FL. A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug And Alcohol Dependence 2010, 112: 178-193. PMID: 20705402, PMCID: PMC2997193, DOI: 10.1016/j.drugalcdep.2010.06.014.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHealth care utilizationHIV treatment outcomesAlcohol use disorderPoor HIV treatment outcomesCare utilizationTreatment outcomesAntiretroviral therapyUse disordersImpact of AUDHealth service utilizationHIV/AIDSCD4 countHIV statusMedication adherenceService utilizationDATA SYNTHESISAnimal studiesElectronic databasesSystematic reviewAlcohol useTherapyPrimary articlesGoogle ScholarAdherenceOutcomesNeurocognitive Impairment and HIV Risk Factors: A Reciprocal Relationship
Anand P, Springer SA, Copenhaver MM, Altice FL. Neurocognitive Impairment and HIV Risk Factors: A Reciprocal Relationship. AIDS And Behavior 2010, 14: 1213-1226. PMID: 20232242, PMCID: PMC2906682, DOI: 10.1007/s10461-010-9684-1.Peer-Reviewed Original ResearchMeSH KeywordsAntiretroviral Therapy, Highly ActiveCognition DisordersHIV InfectionsHumansMedication AdherenceRisk FactorsRisk-TakingSubstance-Related DisordersConceptsRisk reduction interventionsMedication adherenceCognitive impairmentRisk behaviorsHIV risk factorsHIV risk behaviorsImpact of HIVEffectiveness of interventionsSuboptimal adherenceRisk factorsNeurocognitive impairmentMental illnessCognitive functionSubstance abuseImpairmentAdherenceHIVInterventionReciprocal relationshipRiskSignificant barriersPreparing for highly active antiretroviral therapy rollout in rural South Africa: an assessment using the information, motivation, and behavioral skills model
Simon MD, Altice FL, Moll AP, Shange M, Friedland GH. Preparing for highly active antiretroviral therapy rollout in rural South Africa: an assessment using the information, motivation, and behavioral skills model. AIDS Care 2010, 22: 462-474. PMID: 20204909, DOI: 10.1080/09540120903220253.Peer-Reviewed Original ResearchConceptsActive antiretroviral therapy rolloutAntiretroviral therapy rolloutHIV/AIDSHAART rolloutHAART outcomesFolk remediesHIV treatment optimismMedication-taking behaviorOverall correct scoreBetter treatment outcomesResource-limited settingsBehavioral skills modelCommunity-based assessmentHAART initiationHIV optimismHIV testingHIV serostatusTreatment optimismTreatment outcomesSide effectsRural South AfricaCondom useHAARTTugela FerryYoung adults
2007
Initiation, Adherence, and Retention in a Randomized Controlled Trial of Directly Administered Antiretroviral Therapy
Maru DS, Bruce RD, Walton M, Mezger JA, Springer SA, Shield D, Altice FL. Initiation, Adherence, and Retention in a Randomized Controlled Trial of Directly Administered Antiretroviral Therapy. AIDS And Behavior 2007, 12: 284-293. PMID: 18085432, PMCID: PMC2693908, DOI: 10.1007/s10461-007-9336-2.Peer-Reviewed Original ResearchConceptsSelf-administered therapyAntiretroviral therapyDrug usersComposite adherence scorePresence of depressionDrug treatment programsControlled TrialsSix-month periodAdherence scoreOwn medicationsHealth outcomesDAARTMajor causeTherapyAdherenceDiscontinuationHIVSuccessful program designTrialsParticipantsHospitalizationMedicationsLack of willingnessVisitsSuperiority of Directly Administered Antiretroviral Therapy over Self-Administered Therapy among HIV-Infected Drug Users: A Prospective, Randomized, Controlled Trial
Altice FL, Maru DS, Bruce RD, Springer SA, Friedland GH. Superiority of Directly Administered Antiretroviral Therapy over Self-Administered Therapy among HIV-Infected Drug Users: A Prospective, Randomized, Controlled Trial. Clinical Infectious Diseases 2007, 45: 770-778. PMID: 17712763, PMCID: PMC2693907, DOI: 10.1086/521166.Peer-Reviewed Original ResearchConceptsHIV-1 RNA levelsSelf-administered therapyT-lymphocyte countsDrug usersAntiretroviral therapyLymphocyte countRNA levelsPrimary outcomeProportion of patientsGreater mean reductionHIV treatment programsLog10 copies/Human immunodeficiency virusCopies/mLDAART groupVirologic outcomesSecondary outcomesControlled TrialsImmunodeficiency virusPoor adherenceTreatment adherenceEntry criteriaTreat approachCopies/Mean changeAntiretroviral Treatment Regimen Outcomes Among HIV-Infected Prisoners
Springer SA, Friedland GH, Doros G, Pesanti E, Altice FL. Antiretroviral Treatment Regimen Outcomes Among HIV-Infected Prisoners. HIV Research & Clinical Practice 2007, 8: 205-212. PMID: 17720660, PMCID: PMC2409059, DOI: 10.1310/hct0804-205.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyImmunological outcomesHIV-1 RNA levelsCells/mulActive antiretroviral therapyEffective antiretroviral therapyRetrospective cohort studyDuration of therapyKaplan-Meier curvesHIV-1 RNAProportion of subjectsHAART strategyTriple NRTICohort studyCopies/Incarceration periodsTreatment strategiesHigh prevalenceMean changeStudy groupNRTIsHIVTherapyRNA levelsLaboratory data
2006
Buprenorphine and HIV Primary Care: New Opportunities for Integrated Treatment
Khalsa J, Vocci F, Altice F, Fiellin D, Miller V. Buprenorphine and HIV Primary Care: New Opportunities for Integrated Treatment. Clinical Infectious Diseases 2006, 43: s169-s172. PMID: 17109302, DOI: 10.1086/508179.BooksMeSH KeywordsAntiretroviral Therapy, Highly ActiveBuprenorphineDelivery of Health Care, IntegratedFemaleFollow-Up StudiesHealth Services ResearchHIV InfectionsHumansIncidenceMaleNarcotic AntagonistsOpioid-Related DisordersPrimary Health CarePrimary PreventionRisk AssessmentSurvival AnalysisTreatment OutcomeUnited StatesConceptsHuman immunodeficiency virusDrug abuseCare settingsTreatment of HIVHIV primary care settingPrimary HIV care settingsMental Health Services AdministrationHIV primary careProvision of buprenorphineActive antiretroviral therapyHIV care settingsPrimary care settingCollaborative HIV ResearchHealth Services AdministrationAddiction/dependenceAntiretroviral therapyHIV infectionImmunodeficiency syndromeImmunodeficiency virusPrimary careSuccessful treatmentDrug abusersHIV researchDisease controlSubstance abuseRandomized, Controlled Trials of Directly Administered Antiretroviral Therapy for HIV-Infected Patients: Questions about Study Population and Analytical Approach
Smith-Rohrberg D, Altice FL. Randomized, Controlled Trials of Directly Administered Antiretroviral Therapy for HIV-Infected Patients: Questions about Study Population and Analytical Approach. Clinical Infectious Diseases 2006, 43: 1221-1222. PMID: 17029149, DOI: 10.1086/508357.Peer-Reviewed Original ResearchMeSH KeywordsAntiretroviral Therapy, Highly ActiveCase ManagementCase-Control StudiesClinical Trials as TopicFemaleHIV InfectionsHumansPatient CompliancePregnancyRandomized Controlled Trials as TopicModels for Integrating Buprenorphine Therapy into the Primary HIV Care Setting
Basu S, Rohrberg D, Bruce RD, Altice FL. Models for Integrating Buprenorphine Therapy into the Primary HIV Care Setting. Clinical Infectious Diseases 2006, 42: 716-721. PMID: 16447120, DOI: 10.1086/500200.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBuprenorphineHIV InfectionsHumansNarcotic AntagonistsOpioid-Related DisordersPrimary Health CareConceptsBuprenorphine maintenance therapyHIV care settingsMaintenance therapyHIV servicesCare settingsPrimary HIV care settingsSite specialistHIV care providersInjection drug useHuman immunodeficiency virusNegative clinical outcomesPrimary care modelDrug treatment modelAntiretroviral therapyHIV careBuprenorphine therapyClinical outcomesImmunodeficiency virusClinic settingOpiate useCare modelCare providersOpiate dependenceDrug useTherapy services