2019
Adherence to HIV treatment regimens: systematic literature review and meta-analysis
Altice F, Evuarherhe O, Shina S, Carter G, Beaubrun AC. Adherence to HIV treatment regimens: systematic literature review and meta-analysis. Patient Preference And Adherence 2019, 13: 475-490. PMID: 31040651, PMCID: PMC6452814, DOI: 10.2147/ppa.s192735.Peer-Reviewed Original ResearchViral suppressionTreatment adherenceAntiretroviral therapySystematic reviewART adherence levelsComplete treatment regimenHigher adherence ratesHuman immunodeficiency virusSuboptimal treatment adherenceHigh treatment adherenceLevel of adherenceObservational settingTablet regimensPill burdenART adherenceRegimen complexityTablet burdenTreatment regimenImmunodeficiency virusAdherence ratesHIV treatmentObservational studyAdherence levelsMeta-AnalysisViral transmission
2016
Cost-Effectiveness of Single- Versus Generic Multiple-Tablet Regimens for Treatment of HIV-1 Infection in the United States
Sweet DE, Altice FL, Cohen CJ, Vandewalle B. Cost-Effectiveness of Single- Versus Generic Multiple-Tablet Regimens for Treatment of HIV-1 Infection in the United States. PLOS ONE 2016, 11: e0147821. PMID: 26808503, PMCID: PMC4725959, DOI: 10.1371/journal.pone.0147821.Peer-Reviewed Original ResearchConceptsSingle-tablet regimensSubstantial price reductionsTenofovir disoproxil fumarate/emtricitabineCost-effectiveness thresholdIncremental cost-effectiveness ratioGeneric medicationsDaily single-tablet regimensDisoproxil fumarate/emtricitabineCost-effectiveness ratioElvitegravir/cobicistatCombination antiretroviral therapyHIV-1 patientsSingle-tablet regimenHigher inpatient costsHIV-1 infectionIncremental lifetime costPrice reductionEconomic outcomesMicrosimulation modelSuch policiesGeneric lamivudineTablet regimensAntiretroviral therapyU.S. settingsComplex regimens