2022
Clinic-Integrated Mobile Health Intervention (“JomPrEP” App) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Protocol for an Intervention Development and Multiphase Trial
Shrestha R, Wickersham J, Khati A, Azwa I, Ni Z, Kamarulzaman A, Sullivan P, Jadkarim L, Eger W, Gautam K, Altice F. Clinic-Integrated Mobile Health Intervention (“JomPrEP” App) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Protocol for an Intervention Development and Multiphase Trial. JMIR Research Protocols 2022, 11: e43318. PMID: 36542425, PMCID: PMC9813821, DOI: 10.2196/43318.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERPre-exposure prophylaxisHIV prevention servicesHIV testingMalaysian MSMPhase IHIV preventionPrevention servicesLarge-scale efficacy trialsHIV prevention resourcesMobile health interventionsHIV prevention effortsCare delivery servicesHealth care delivery servicesMultiphase trialPrEP servicesMiddle-income countriesHIV epidemicEfficacy trialsTrial designPrevention strategiesEntrenched stigmaHealth outcomesReal-world settingHealth interventions
2020
Hazardous alcohol use, antiretroviral therapy receipt, and viral suppression in people living with HIV who inject drugs in the United States, India, Russia, and Vietnam.
Wagman JA, Wynn A, Matsuzaki M, Gnatienko N, Metsch LR, Del Rio C, Feaster DJ, Nance RM, Whitney BM, Delaney JAC, Kahana SY, Crane HM, Chandler RK, Elliott JC, Altice F, Lucas GM, Mehta SH, Hirsch-Moverman Y, El-Sadr WM, Vu Q, Nguyen Thanh B, Springer SA, Tsui JI, Samet JH. Hazardous alcohol use, antiretroviral therapy receipt, and viral suppression in people living with HIV who inject drugs in the United States, India, Russia, and Vietnam. AIDS 2020, 34: 2285-2294. PMID: 33048870, PMCID: PMC7951611, DOI: 10.1097/qad.0000000000002716.Peer-Reviewed Original ResearchConceptsHazardous alcohol useFormer injection drug useART receiptViral suppressionInjection drug useLow-middle income countriesAlcohol useAntiretroviral therapyMiddle-income countriesDrug useAlcohol Use Disorders Identification Test (AUDIT) scoresHIV viral suppressionAlcohol Use Disorders Identification TestDisorders Identification TestTherapy receiptHIV continuumMean ageHigh-income countriesCare outcomesLogistic regressionUpper middle-income countriesPLHIVDrugsIdentification TestHIV
2017
Primary healthcare-based integrated care with opioid agonist treatment: First experience from Ukraine
Morozova O, Dvoriak S, Pykalo I, Altice FL. Primary healthcare-based integrated care with opioid agonist treatment: First experience from Ukraine. Drug And Alcohol Dependence 2017, 173: 132-138. PMID: 28242537, PMCID: PMC5545131, DOI: 10.1016/j.drugalcdep.2016.12.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCross-Sectional StudiesDelivery of Health Care, IntegratedFemaleHealth Services ResearchHIV InfectionsHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient DropoutsPatient SatisfactionPilot ProjectsPrimary Health CareQuality of LifeSubstance Abuse, IntravenousUkraineConceptsOpioid agonist therapyPrimary healthcare clinicsIntegrated carePHC staffHIV patientsHIV epidemicOAT patientsOpioid agonist treatmentStandard of careAddiction treatment settingsAgonist therapyObservational cohortMiddle-income countriesAgonist treatmentPrimary careComprehensive healthcare servicesPWIDHealthcare clinicsAddiction clinicPatientsTreatment settingsDrug usersPilot studyCareHealthcare services
2016
Community-Based Interventions to Improve and Sustain Antiretroviral Therapy Adherence, Retention in HIV Care and Clinical Outcomes in Low- and Middle-Income Countries for Achieving the UNAIDS 90-90-90 Targets
Nachega JB, Adetokunboh O, Uthman OA, Knowlton AW, Altice FL, Schechter M, Galárraga O, Geng E, Peltzer K, Chang LW, Van Cutsem G, Jaffar SS, Ford N, Mellins CA, Remien RH, Mills EJ. Community-Based Interventions to Improve and Sustain Antiretroviral Therapy Adherence, Retention in HIV Care and Clinical Outcomes in Low- and Middle-Income Countries for Achieving the UNAIDS 90-90-90 Targets. Current HIV/AIDS Reports 2016, 13: 241-255. PMID: 27475643, PMCID: PMC5357578, DOI: 10.1007/s11904-016-0325-9.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsCommunity Health CentersCross-Sectional StudiesDeveloping CountriesHealth EducationHealth Services AccessibilityHIV InfectionsHumansMedication AdherenceObservational Studies as TopicPatient DropoutsRandomized Controlled Trials as TopicSustained Virologic ResponseUnited NationsConceptsHealth facility-based interventionsFacility-based interventionsAntiretroviral therapy adherenceCommunity-based interventionsVirologic suppressionCohort studyMiddle-income countriesClinical outcomesTherapy adherenceRelative riskComparable outcomesCommunity-based ART delivery modelTreatment engagementART delivery modelsFacility-based modelsComparative cohort studyRelevant clinical outcomesRandom-effects modelLeast comparable outcomesStable HIVCause mortalityHIV careART adherenceUNAIDS 90ART deliveryClinical care of incarcerated people with HIV, viral hepatitis, or tuberculosis
Rich JD, Beckwith CG, Macmadu A, Marshall BDL, Brinkley-Rubinstein L, Amon JJ, Milloy MJ, King MRF, Sanchez J, Atwoli L, Altice FL. Clinical care of incarcerated people with HIV, viral hepatitis, or tuberculosis. The Lancet 2016, 388: 1103-1114. PMID: 27427452, PMCID: PMC5504684, DOI: 10.1016/s0140-6736(16)30379-8.Peer-Reviewed Original ResearchConceptsClinical careCommunity-based health careJail settingsHealth careDelivery of careCommunity-based treatmentProvision of treatmentHIV/AIDSPrison health careHepatitis BViral hepatitisMiddle-income countriesC virusClinical managementHigh-income countriesGeneral populationMedical careMental illnessInfectious diseasesOptimal deliverySubstance useCareTransmissible diseasesHIVTuberculosis
2014
Latent tuberculosis infection in a Malaysian prison: implications for a comprehensive integrated control program in prisons
Al-Darraji HA, Kamarulzaman A, Altice FL. Latent tuberculosis infection in a Malaysian prison: implications for a comprehensive integrated control program in prisons. BMC Public Health 2014, 14: 22. PMID: 24405607, PMCID: PMC3907782, DOI: 10.1186/1471-2458-14-22.Peer-Reviewed Original ResearchConceptsTuberculin skin testLatent TB infectionNational TB incidence rateMalaysia's largest prisonSubstance abuse componentLatent tuberculosis infectionTB incidence rateTB control programsPPD RT 23Overall national rateProblem of tuberculosisLargest prisonLogistic regression modelsHIV-uninfectedIntegrated tuberculosisMethodsFrom JulyConclusionsThe prevalenceTB infectionActive tuberculosisTB screeningTST positivityMiddle-income countriesTuberculosis infectionHIV statusSkin test
2013
Integration of health services improves multiple healthcare outcomes among HIV-infected people who inject drugs in Ukraine
Bachireddy C, Soule MC, Izenberg JM, Dvoryak S, Dumchev K, Altice FL. Integration of health services improves multiple healthcare outcomes among HIV-infected people who inject drugs in Ukraine. Drug And Alcohol Dependence 2013, 134: 106-114. PMID: 24128379, PMCID: PMC3865106, DOI: 10.1016/j.drugalcdep.2013.09.020.Peer-Reviewed Original ResearchConceptsOpioid substitution therapyOpioid-dependent PWIDIsoniazid preventive therapyHealth-related qualityNeedles/syringesHIV-endemic regionsComposite scoreCross-sectional studyHealthcare quality indicatorsAntiretroviral therapyTuberculosis servicesPreventive therapySecondary outcomesHigher HRQoLMiddle-income countriesPrimary outcomePoor outcomeSubstitution therapyPotential confoundersTuberculosis treatmentHIV epidemicHIVHealth servicesPWIDOutreach settings
2012
Isoniazid preventive therapy in correctional facilities: a systematic review [Review article]
Al-Darraji HA, Kamarulzaman A, Altice FL. Isoniazid preventive therapy in correctional facilities: a systematic review [Review article]. The International Journal Of Tuberculosis And Lung Disease 2012, 16: 871-879. PMID: 22410101, DOI: 10.5588/ijtld.11.0447.Peer-Reviewed Original ResearchConceptsIsoniazid preventive therapyIPT initiationPreventive therapySystematic reviewHuman immunodeficiency virus statusCompletion ratesPrevalent adverse reactionsCorrectional facilitiesIPT effectivenessTreatment interruptionActive tuberculosisViral hepatitisMiddle-income countriesTB controlAdverse reactionsRisk factorsVirus statusEligible studiesCommunity settingsTuberculosisLow-income countriesMajor causeJail settingsAdverse effectsInternational recommendations