2024
Urine Biomarkers of Kidney Tubule Health and Risk of Incident CKD in Persons Without Diabetes: The ARIC, MESA, and REGARDS Studies
Amatruda J, Katz R, Rebholz C, Sarnak M, Gutierrez O, Schrauben S, Greenberg J, Coresh J, Cushman M, Waikar S, Parikh C, Schelling J, Jogalekar M, Bonventre J, Vasan R, Kimmel P, Ix J, Shlipak M, Consortium C. Urine Biomarkers of Kidney Tubule Health and Risk of Incident CKD in Persons Without Diabetes: The ARIC, MESA, and REGARDS Studies. Kidney Medicine 2024, 6: 100834. PMID: 38826568, PMCID: PMC11141432, DOI: 10.1016/j.xkme.2024.100834.Peer-Reviewed Original ResearchAssociated with incident chronic kidney diseaseIncident chronic kidney diseaseChronic kidney diseaseUrine MCP-1Meta-analysisUrine biomarkersMCP-1A1M concentrationsMultivariable Cox proportional hazards regressionRisk of chronic kidney diseaseRisk of incident chronic kidney diseaseCox proportional hazards regressionIndependent of eGFRPrevalent chronic kidney diseaseCohort of adultsMeta-analysis of resultsA1MLong follow-up periodEarly chronic kidney diseaseFollow-up periodProportional hazards regressionUrine A1MARIC participantsREGARDS studyHealth markers
2023
Plasma Biomarkers and Incident CKD Among Individuals Without Diabetes
Le D, Chen J, Shlipak M, Ix J, Sarnak M, Gutierrez O, Schelling J, Bonventre J, Sabbisetti V, Schrauben S, Coca S, Kimmel P, Vasan R, Grams M, Parikh C, Coresh J, Rebholz C, Consortium C. Plasma Biomarkers and Incident CKD Among Individuals Without Diabetes. Kidney Medicine 2023, 5: 100719. PMID: 37841418, PMCID: PMC10568645, DOI: 10.1016/j.xkme.2023.100719.Peer-Reviewed Original ResearchSoluble urokinase plasminogen activator receptorKidney injury molecule-1Incident chronic kidney diseaseChronic kidney diseaseLevels of kidney injury molecule-1Development of kidney diseaseMonocyte chemoattractant protein-1Kidney diseaseTNFR-2TNFR-1Development of chronic kidney diseaseConcentrations of kidney injury molecule-1Odds of incident chronic kidney diseaseAssociated with incident chronic kidney diseaseTumor necrosis factor receptor 2Urokinase plasminogen activator receptorCases of incident CKDYears of follow-upTumor necrosis factor receptor 1AbstractText Label="PLAIN-LANGUAGE SUMMARYBaseline plasma biomarkersHuman cartilage glycoprotein-39Kidney disease progressionPlasminogen activator receptorChemoattractant protein-1