2016
Wide variations in blood product transfusion practices among providers who care for patients with acute leukemia in the United States
Pine AB, Lee E, Sekeres M, Steensma DP, Zelterman D, Prebet T, DeZern A, Komrokji R, Litzow M, Luger S, Stone R, Erba HP, Garcia‐Manero G, Lee AI, Podoltsev NA, Barbarotta L, Kasberg S, Hendrickson JE, Gore SD, Zeidan AM. Wide variations in blood product transfusion practices among providers who care for patients with acute leukemia in the United States. Transfusion 2016, 57: 289-295. PMID: 27878822, PMCID: PMC5309168, DOI: 10.1111/trf.13934.Peer-Reviewed Original ResearchConceptsAcute leukemiaTransfusion practiceBlood productsTransfusion patternsAL patientsHigh-quality trial evidenceBlood product transfusionBone marrow biopsyEvidence-based guidelinesClinical outcome dataRed blood cell productsBlood cell productsTransfusion goalsProduct transfusionTransfusion triggerUnnecessary transfusionsAmbulatory patientsCryoprecipitate transfusionMarrow biopsyTrial evidenceLumbar punctureSupportive managementCare settingsInvasive proceduresOutcome data
2015
Patterns of Venous Thromboembolism Prophylaxis during Inpatient Treatment of Acute Leukemia: Results of a North American Web-Based Survey
Lee E, Smith B, Merrey J, Lee A, Podoltsev N, Barbarotta L, Litzow M, Prebet T, Luger S, Gore S, Streiff M, Zeidan A. Patterns of Venous Thromboembolism Prophylaxis during Inpatient Treatment of Acute Leukemia: Results of a North American Web-Based Survey. Blood 2015, 126: 4455. DOI: 10.1182/blood.v126.23.4455.4455.Peer-Reviewed Original ResearchECOG-ACRIN Cancer Research GroupVTE prophylaxisEvidence-based guidelinesVenous thromboembolismCancer Research GroupAcute leukemiaAL patientsConsolidation therapyPharmacologic prophylaxisVTE preventionPlatelet countPractice patternsJohns Hopkins Institutional Review BoardWeb-based surveyLimited high-quality studiesPharmacologic VTE prophylaxisVTE prophylaxis practicesVenous thromboembolism prophylaxisSequential compression devicesPlatelet count thresholdQuestion web-based surveyHigh-quality studiesInstitutional review boardProphylactic anticoagulationThromboembolism prophylaxisPatterns of Venous Thromboembolism Prophylaxis During Treatment of Acute Leukemia: Results of a North American Web-Based Survey
Lee EJ, Smith BD, Merrey JW, Lee AI, Podoltsev NA, Barbarotta L, Litzow MR, Prebet T, Luger SM, Gore S, Streiff MB, Zeidan AM. Patterns of Venous Thromboembolism Prophylaxis During Treatment of Acute Leukemia: Results of a North American Web-Based Survey. Clinical Lymphoma Myeloma & Leukemia 2015, 15: 766-770.e4. PMID: 26363982, PMCID: PMC4663156, DOI: 10.1016/j.clml.2015.07.637.Peer-Reviewed Original ResearchConceptsVenous thromboembolismAcute leukemiaVTE prophylaxisPrevention of VTEPharmacologic VTE prophylaxisVenous thromboembolism prophylaxisEvidence-based guidelinesHigh-quality studiesConsolidation therapyPharmacologic prophylaxisThromboembolism prophylaxisNorth American providersVTE preventionSignificant morbidityProspective studyPatient populationHigh riskProphylaxisLower riskResponse ratePatientsWeb-based surveyLeukemiaSpectrum of practicesAmerican providers