YCC Publications 2024

December 17, 2024

Cancer research

Recent cancer-related publications by Yale Cancer Center members and Yale School of Medicine affiliates

DECEMBER

Perioperative safety of risk-reducing mastectomy. Knoedler S, Diatta F, Kasparbauer F, Knoedler L, Kim BS, Pomahac B, Kauke-Navarro M. Br J Cancer. 2024 Dec;131(11):1721-1723.

Phosphoenolpyruvate carboxykinase-2 (PCK2) is a therapeutic target in triple-negative breast cancer. Gunasekharan V, Lin HK, Marczyk M, Rios-Hoyo A, Campos GE, Shan NL, Ahmed M, Umlauf S, Gareiss P, Raaisa R, Williams R, Cardone R, Siebel S, Kibbey R, Surovtseva YV, Pusztai L. Breast Cancer Res Treat. 2024 Dec;208(3):657-671.

Brief Report: Should a prior cancer history be reevaluated as an exclusion for clinical trial participation? Ayoade O, Canavan ME, Caturegli G, Boffa DJ. Lung Cancer. 2024 Dec;198:108032.

Comprehensive functional evaluation of head and neck squamous cell carcinoma with BH3-profiling demonstrates apoptotic competency and therapeutic efficacy of BH3-mimetics. Li D, Lopez A, Shrivastava N, Chan W, Thomas C, Burk R, Segall J, Augustine S, Rosenblatt G, Mehta V, Schiff BA, Smith RV, Prystowsky MB, Schlecht NF, Guha C, Gavathiotis E, Ow TJ. Oral Oncol. 2024 Dec;159:107069.

NOVEMBER

Factors influencing timely diagnosis in neurolymphomatosis. Doubrovinskaia S, Egert A, Karschnia P, Scheffler GT, Traub BL, Galluzzo D, Huttner A, Fulbright RK, Baehring JM, Kaulen LD. J Neurooncol. 2024 Nov;170(2):309-317.

Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020. Ajjawi I, Loeb S, Cooperberg MR, Catalona WJ, Gross CP, Ma X, Leapman MS. JAMA. 2024 Nov 20:e2420580.

Vaping and tumor metastasis: current insights and progress. Xi Y, Yang L, Burtness B, Wang H. Cancer Metastasis Rev. 2024 Nov 25;44(1):4.

By Any Other Name: Bowel Dysfunction After Proctectomy for Cancer and Its Predictive Factors in Administrative Databases. Leeds IL, Coppersmith NA, Moore MS, Saleh A, Cruickshank K, Pantel H, Reddy V, Mongiu AK. J Surg Res. 2024 Nov;303:342-351.

Risk Score for Hepatocellular Cancer in Adults Without Viral Hepatitis or Cirrhosis. Ilagan-Ying YC, Gordon KS, Tate JP, Lim JK, Torgersen J, Lo Re V 3rd, Justice AC, Taddei TH. JAMA Netw Open. 2024 Nov 4;7(11):e2443608.

ASO Visual Abstract: Series on the Lancet Oncology Commission on Global Cancer Surgery : Action 1-Clinical Care and Access to Cancer Surgery. Are C, Schissel M, Murthy S. Ann Surg Oncol. 2024 Nov 13.

The Association Between Medical Insurance, Access to Care, and Outcomes for Patients with Uveal Melanoma in the United States. Marks VA, Williams BK Jr, Leapman MS, Shields CL. Semin Ophthalmol. 2024 Nov 9:1-12.

PARG inhibition induces nuclear aggregation of PARylated PARP1. Paradkar S, Purcell J, Cui A, Friedman S, Noronha KJ, Murray MA, Sundaram RK, Bindra RS, Jensen RB. Structure. 2024 Nov 7;32(11):2083-2093.e5.

Single‑center, retrospective, evaluator‑blinded, pilot and pivotal clinical trials: Assessing the mirCaP Kit (hsv2‑miR‑H9/hsa‑miR‑3659) as a diagnostic marker for prostate cancer in patients with PSA levels in the gray zone. Kim WT, Kim K, Kang HW, Byun YJ, Piao XM, Kim YJ, Lee SC, Yun SJ, Ha YS, Kim J, Kim IY. Oncol Letters. 2024 Oct 23;29(1):23

A landmark federal interagency collaboration to promote data science in health care: Million Veteran Program-Computational Health Analytics for Medical Precision to Improve Outcomes Now. Justice AC, McMahon B, Madduri R, Crivelli S, Damrauer S, Cho K, Ramoni R, Muralidhar S. JAMIA Open. 2024 Nov 6;7(4):ooae126

Radiomics-driven personalized radiotherapy for primary and recurrent tumors: A general review with a focus on reirradiation. Beddok A, Orlhac F, Rozenblum L, Calugaru V, Créhange G, Dercle L, Nioche C, Thariat J, Marin T, El Fakhri G, Buvat I. Cancer Radiother. 2024 Nov;28(6-7):597-602.

OCTOBER

Safe and Effective Treatment of Refractory Cancer Pain with Chronic Oral Ketamine: A Case Series,
Dmitry Kozhevnikov, DO, FACP, Lava Kareem, PharmD, and Trinh Bui Palliative Medicine Reports. doi.org/10.1089/pmr.2024.0049

Doing Justice: Ethical Considerations Identifying and Researching Transgender and Gender Diverse People in Insurance Claims Data. Alpert AB, Babbs G, Sanaeikia R, Ellison J, Hughes L, Herington J, Dembroff R. J Med Syst. 2024 Oct 12;48(1):96. doi: 10.1007/s10916-024-02111-w. PMID: 39394534; PMCID: PMC11469973.

Acyl-CoA Synthetase Medium-Chain Family Member 5-Mediated Fatty Acid Metabolism Dysregulation Promotes the Progression of Hepatocellular Carcinoma. Yang L, Pham K, Xi Y, Jiang S, Robertson KD, Liu C. Am J Pathol. 2024 Oct;194(10):1951-1966.

The science and practice of imaging-based screening: What the radiologist needs to know. Milch HS, Haramati LB. Clin Imaging. 2024 Oct;114:110266.

Patterns of Physical Therapy Referral and Subsequent Attendance Among Childhood Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy at a Regional Childhood Cancer Survivorship Clinic. Kang L, Kadan-Lottick NS, Rotatori J, Kujawski SE, Messerschmidt E, Auerbach C, Balsamo LM, Lustberg MB, Ma X, Rodwin RL. Semin Oncol Nurs. 2024 Oct;40(5):151716.

Multimodality Treatment for Locally Advanced Gastric Adenocarcinoma, Thejal Srikumar, Raghav Sundar, Surgical Clinics of North America, 2024, ISSN 0039-6109, https://doi.org/10.1016/j.suc.2024.06.007

Disentangling gender, sex, and biology: a mixed methods study of gender identity data collection tools. Ash B. Alpert, Tresne Hernandez, Roman Ruddick, Charlie Manzano, Spencer Adams, Lex Rivers, Alixida Ramos-Pibernus, Jae Sevelius, Tonia Poteat, Juno Obedin-Maliver, Ethan C. Cicero, Asa Radix, Elle Lett, Don Operario, Ben Chapman, Marsha Wittink, AnaPaula Cupertino, Gabriel R. Murchison, Marcella Nunez-Smith, Francisco Cartujano-Barrera. Patient Education and Counseling, 2024, 108473, ISSN 0738-3991 .

Diagnostic experiences of Black and White patients with uterine cancer: A qualitative study. Britton MC, Izampuye E, Clark M, Ornstein RA, Nunez-Smith M, Wright JD, Xu X. Gynecol Oncol. 2024 Oct 2;191:67-73.

Safe and Effective Treatment of Refractory Cancer Pain with Chronic Oral Ketamine: A Case Series .Palliative Medicine Reports 2024 5:1, 475-480

Selective Estrogen Receptor Degraders (SERDs) Taylor, M., Kahn, A. & Foldi, J. Curr Breast Cancer Rep 16, 402–416 (2024). https://doi.org/10.1007/s12609-024-00563-0

TROPHY-U-01 Cohort 2: A Phase II Study of Sacituzumab Govitecan in Cisplatin-Ineligible Patients With Metastatic Urothelial Cancer Progressing After Previous Checkpoint Inhibitor Therapy. Petrylak DP, Tagawa ST, Jain RK, Bupathi M, Balar A, Kalebasty AR, George S, Palmbos P, Nordquist L, Davis N, Ramamurthy C, Sternberg CN, Loriot Y, Agarwal N, Park C, Tonelli J, Vance M, Zhou H, Grivas P. J Clin Oncol. 2024 Oct 10;42(29):3410-3420.

Efficacy and Safety of Sacituzumab Govitecan in Patients With Advanced Solid Tumors (TROPiCS-03): Analysis in Patients With Advanced Endometrial Cancer. Santin AD, Corr BR, Spira A, Willmott L, Butrynski J, Tse KY, Patel J, Mekan S, Wu T, Lin KW, Kuo P, Dumbrava EE. J Clin Oncol. 2024 Oct 10;42(29):3421-3429.

Bacterial small molecule metabolites implicated in gastrointestinal cancer development. Turocy T, Crawford JM. Nat Rev Microbiol. 2024 Oct 7.

Unmet needs in cervical cancer - can biological therapies plug the gap? Greenman M, Chang YE, McNamara B, Mutlu L, Santin AD. Expert Opin Biol Ther. 2024 Oct;24(10):995-1003. doi: 10.1080/14712598.2024.2408754. Epub 2024 Sep 25. PMID: 39311611.

SEPTEMBER

Mutational Features and Tumor Microenvironment Alterations in High-Grade Appendiceal Cancers Treated With Iterative Hyperthermic Intraperitoneal Chemotherapy. Su DG, Dhiman A, Bansal VV, Zha Y, Shergill A, Polite B, Alpert L, Turaga KK, Eng OS. JCO Precis Oncol. 2024 Sep;8:e2400149.

National Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer. Kim LS, Moore MS, Schneider E, Canner J, Ayyala H, Chen J, Anant P, Graetz E, Lynch MA, Zanieski G, Gillego A, Valero MG, Proussaloglou EM, Berger ER, Golshan M, Greenup RA, Park TS. Ann Surg Oncol. 2024 Sep 25.

An elevated rate of whole-genome duplications in cancers from Black patients. Brown LM, Hagenson RA, Koklič T, Urbančič I, Qiao L, Strancar J, Sheltzer JM. Nat Commun. 2024 Sep 19;15(1):8218.

Collapsed State Mediates the Low Fidelity of the DNA Polymerase β I260 Mutant. Biochemistry. Fijen C, Chavira C, Alnajjar K, Sawyer DL, Sweasy JB. 2024 Oct 1;63(19):2414-2424. doi: 10.1021/acs.biochem.4c00263. Epub 2024 Sep 19.

tural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer. Lindsay ME, de Oliveira S, Sciacca K, Lindvall C, Ananth PJ. JCO Clin Cancer Inform. 2024 Sep;8:e2400134.

Keep It Moving: Physical Activity in the Prevention of Obesity-Driven Pancreatic Cancer. Sogunro A, Muzumdar MD. Cancer Res. 2024 Sep 16;84(18):2935-2937.

Pancreatic Cysts. Gonda TA, Cahen DL, Farrell JJ. N Engl J Med. 2024 Sep 5;391(9):832-843. doi: 10.1056/NEJMra2309041. PMID: 39231345.

Adaptation of the socioecological model to address disparities in engagement of Black men in prostate cancer genetic testing. Leader AE, Rebbeck TR, Oh WK, Patel AV, Winer EP, Bailey LO, Gomella LG, Lumpkins CY, Garraway IP, Aiello LB, Baskin ML, Cheng HH, Cooney KA, Ganzak A, George DJ, Halabi S, Hathaway F, Healy C, Kim JW, Leapman MS, Loeb S, Maxwell KN, McNair C, Morgan TM, Prindeville B, Soule HR, Steward WL, Suttiratana SC, Taplin ME, Yamoah K, Fortune T, Bennett K, Blanding-Godbolt J, Gross L, Giri VN. BMC Public Health. 2024 Sep 18;24(1):2533.

Quantitative Measurement of HER2 Expression in Non-Small Cell Lung Cancer With a High-Sensitivity Assay. Liu M, Vathiotis I, Robbins CJ, Chan NNN, Moutafi M, Burela S, Xirou V, Schalper KA, Herbst RS, Syrigos K, Rimm DL. Mod Pathol. 2024 Sep;37(9):100556.

Patterns of brain metastases response to immunotherapy with pembrolizumab. Mahajan A, Goldberg SL, Weiss SA, Tran T, Singh K, Joshi K, Aboian MS, Kluger HM, Chiang VL. J Neurooncol. 2024 Sep;169(3):555-561. d

Incidence of Pathologic Nodal Disease in Clinically Node-Negative, Microinvasive or T1a Breast Cancers. Dey P, Kc M, Proussaloglou EM, Khubchandani JA, Kim L, Zanieski G, Park T, Lynch M, Gillego A, Valero M, Schneider E, Golshan M, Greenup RA, Berger ER. Ann Surg Oncol. 2024 Sep 6.

Structural insights into the role and targeting of EGFRvIII. Bagchi A, Stayrook SE, Xenaki KT, Starbird CA, Doulkeridou S, El Khoulati R, Roovers RC, Schmitz KR, van Bergen En Henegouwen PMP, Ferguson KM. Structure. 2024 Sep 5;32(9):1367-1380.e6.

Foundational Models for Pathology and Endoscopy Images: Application for Gastric Inflammation. Kerdegari H, Higgins K, Veselkov D, Laponogov I, Polaka I, Coimbra M, Pescino JA, Leja M, Dinis-Ribeiro M, Fleitas Kanonnikoff T, Veselkov K. Diagnostics (Basel). 2024 Aug 30;14(17):1912.

Clinical and Histologic Variants of CD8+ Cutaneous T-Cell Lymphomas. Swallow MA, Micevic G, Zhou A, Carlson KR, Foss FM, Girardi M. Cancers (Basel). 2024 Sep 5;16(17):3087.

Evaluating Treatment Patterns and the Role of Neoadjuvant Chemotherapy in Plasmacytoid Urothelial Carcinoma: Insights from a Combined National and Institutional Series. Rahman S, Kong V, Jalfon M, Hesse D, Kim J, Wright JL, Adeniran A, Humphrey P, Martin DT, Ghali F.. Cancers (Basel). 2024 Sep 1;16(17):3050.

Inhibition of lysine acetyltransferase KAT6 in ER⁺HER2^- metastatic breast cancer: a phase 1 trial. Mukohara T, Park YH, Sommerhalder D, Yonemori K, Hamilton E, Kim SB, Kim JH, Iwata H, Yamashita T, Layman RM, Mita M, Clay T, Chae YS, Oakman C, Yan F, Kim GM, Im SA, Lindeman GJ, Rugo HS, Liyanage M, Saul M, Le Corre C, Skoura A, Liu L, Li M, LoRusso PM. Nat Med. 2024 Aug;30(8):2371.

Evaluating differences in receipt of survivorship care plan among cancer survivors with and without disabilities. Sarkar S, Zaidi M, Raziani Y, Poghosyan H. Support Care Cancer. 2024 Sep 5;32(10):637. doi: 10.1007/s00520-024-08796-6. PMID: 39235704.

Cost trends of metastatic renal cell carcinoma therapy: the impact of oral anticancer agents and immunotherapy. Forman R, Long JB, Westvold SJ, Agnish K, Mcmanus HD, Leapman MS, Hurwitz ME, Spees LP, Wheeler SB, Gross CP, Dinan MA. JNCI Cancer Spectr. 2024 Sep 2;8(5):pkae067.

EIF1AX mutation in thyroid nodules: a histopathologic analysis of 56 cases in the context of institutional practices. Abi-Raad R, Xu B, Gilani S, Ghossein RA, Prasad ML. EIF1AX mutation in thyroid nodules: a histopathologic analysis of 56 cases in the context of institutional practices. Virchows Arch. 2024 Sep 3.

AUGUST

Comparison of incident breast cancer cases in the largest national US tumor registries. Plichta JK, Thomas SM, Chanenchuk TC, Chan K, Hyslop T, Hwang ES, Greenup RA. Cancer. 2024 Aug 18.

Surgical management of rare tumors (Part 1). Stetson A, Saluja S, Cameron DB, Mansfield SA, Polites SF, Honeyman JN, Dahl JP, Austin MT, Aldrink JH, Christison-Lagay ER. Pediatr Blood Cancer. 2024 Aug 26:e31287.

Associations amongst genes, molecules, cells, and organs in breast cancer metastasis. Nathanson SD, Dieterich LC, Zhang XH, Chitale DA, Pusztai L, Reynaud E, Wu YH, Ríos-Hoyo A. Clin Exp Metastasis. 2024 Aug;41(4):417-437.

Progress in Lung Cancer Screening Adoption. Richman IB, Gross CP. JAMA Intern Med. 2024 Aug 1;184(8):902-903. doi: 10.1001/jamainternmed.2024.1673.

Devimistat (CPI-613) With Modified Fluorouarcil, Oxaliplatin, Irinotecan, and Leucovorin (FFX) Versus FFX for Patients With Metastatic Adenocarcinoma of the Pancreas: The Phase III AVENGER 500 Study. Philip PA, Sahai V, Bahary N, Mahipal A, Kasi A, Rocha Lima CMS, Alistar AT, Oberstein PE, Golan T, Metges JP, Lacy J, Fountzilas C, Lopez CD, Ducreux M, Hammel P, Salem M, Bajor D, Benson AB, Luther S, Pardee T, Van Cutsem E. J Clin Oncol. 2024 Aug 1:JCO2302659.

Associations amongst genes, molecules, cells, and organs in breast cancer metastasis.Nathanson SD, Dieterich LC, Zhang XH, Chitale DA, Pusztai L, Reynaud E, Wu YH, Ríos-Hoyo A. Clin Exp Metastasis. 2024 Aug;41(4):417-437.

BCAM (basal cell adhesion molecule) protein expression in different tumor populations. Burela S, He M, Trontzas IP, Gavrielatou N, Schalper KA, Langermann S, Flies DB, Rimm DL, Aung TN. Discov Oncol. 2024 Aug 29;15(1):381.

Shades of Gray: Do Never Smokers Benefit From Lung Cancer Screening Programs? Woodard GA, Jablons DM. J Thorac Oncol. 2024 Aug;19(8):1135-1137.

Cancer Metrics on Subsequent Screening Rounds: Another Piece in the Complicated Puzzle. Hooley R, Philpotts L. Radiology. 2024 Jul;312(1):e241540

CAR-T and CAR-NK as cellular cancer immunotherapy for solid tumors. Peng L, Sferruzza G, Yang L, Zhou L, Chen S. Cell Mol Immunol. 2024 Aug 12.

Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study. Puklin LS, Irwin ML, Sanft T, Ferrucci LM, Harrigan M, McGowan C, Cartmel B, Zupa M, Winer EP, Deyling M, Ligibel JA, Basen-Engquist K, Spiegelman D, Sharifi M. Support Care Cancer. 2024 Aug 14;32(9):590.

The physical landscape of CAR-T synapse. Xiong Y, Libby KA, Su X. Biophys J. 2024 Aug 6;123(15):2199-2210.

Adaption and National Validation of a Tool for Predicting Mortality from Other Causes Among Men with Nonmetastatic Prostate Cancer. Justice, AC, Tate, JP, Howland, F, Gaziano, JM, Kelley, MJ, Mcmahon, B, Haiman, C, Wadia, R, Madduri, R, Danciu, I, Leppert, JT, Leapman, MS, Thurtle, D, Gnanapragasam, VJ. (2024) European Urology Oncology 7 (4) 923-932

Neoadjuvant Chemotherapy and Immunotherapy for Estrogen Receptor-Positive Human Epidermal Growth Factor 2-Negative Breast Cancer. Ríos-Hoyo A, Cobain E, Huppert LA, Beitsch PD, Buchholz TA, Esserman L, van 't Veer LJ, Rugo HS, Pusztai L. J Clin Oncol. 2024 Aug 1;42(22):2632-2636.

Enhanced intratumoral delivery of immunomodulator MPLA via hyperbranched polyglycerol-coated biodegradable nanoparticles. Chang J, Shin K, Lewis JM, Suh HW, Lee J, Damsky W, Xu S, Bosenberg M, Saltzman WM, Girardi M. J Invest Dermatol. 2024 Aug 7:S0022-202X(24)01983-3.

Cost trends of Metastatic Renal Cell Carcinoma Therapy: the impact of oral anticancer agents and immunotherapy. Forman R, Long JB, Westvold SJ, Agnish K, McManus HD, Leapman MS, Hurwitz ME, Spees LP, Wheeler SB, Gross CP, Dinan MA. JNCI Cancer Spectr. 2024 Aug 12:pkae067.

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights. Rose MG, Kennedy EB, Abou-Alfa GK, Finn RS, Gade T, Kelley RK, Taddei T, Gordan JD. JCO Oncol Pract. 2024 Aug;20(8):1035-1039.

Impact of Social Needs and Identity Experiences on the Burden of Illness in Patients with Multiple Myeloma: A Mixed-Methods Study. Neparidze N, Godara A, Lin D, Le HH, Fixler K, Shea L, Everson S, Brittle C, Brunisholz KD. Healthcare (Basel). 2024 Aug 20;12(16):1660.

Perioperative Modified FOLFIRINOX for Resectable Pancreatic Cancer: A Nonrandomized Controlled Trial. Cecchini M, Salem RR, Robert M, Czerniak S, Blaha O, Zelterman D, Rajaei M, Townsend JP, Cai G, Chowdhury S, Yugawa D, Tseng R, Mejia Arbelaez C, Jiao J, Shroyer K, Thumar J, Kortmansky J, Zaheer W, Fischbach N, Persico J, Stein S, Khan SA, Cha C, Billingsley KG, Kunstman JW, Johung KL, Wiess C, Muzumdar MD, Spickard E, Aushev VN, Laliotis G, Jurdi A, Liu MC, Escobar-Hoyos L, Lacy J. JAMA Oncol. 2024 Aug 1;10(8):1027-1035.

Immunotherapy For US Patients With Metastatic Cancer at the End of Life-Reply. Kerekes D, Khan S. JAMA Oncol. 2024 Aug 1;10(8):1134.

JULY

Underuse of Postoperative Radiation After Nipple-Sparing Mastectomy for Standard Radiation Indications. Talcott WJ, Marta GN, Moran MS. Adv Radiat Oncol. 2024 Jul 14;9(9):101569

A Brief Report of Lung Cancer Screening Utilization Before, During, and in the Later Stages of the COVID-19 Pandemic in the United States. Poghosyan H, Sarkar S, Richman I, Pietrzak RH, Carter-Bawa L, Cooley ME. JTO Clin Res Rep. 2024 Jul 6;5(9):100705.

Cancer Metrics on Subsequent Screening Rounds: Another Piece in the Complicated Puzzle. Radiology. Hooley R, Philpotts L. 2024 Jul;312(1):e241540.

Peripheral Blood Extracellular Vesicle RNA Profiling: The Next Step in Cancer Liquid Biopsies. Ann Surg Oncol. Hu R, Korutla L, Vallabhajosyula P. 2024 Jul;31(7):4179-4181.

Proofreading the way: immune checkpoint inhibitors in polymerase ε/polymerase δ (POLE/POLD1)-altered colorectal cancer. Cecchini M, Sundar R. Ann Oncol. 2024 Jul;35(7):582-584.

Systemic Anticancer Therapy and Overall Survival in Patients With Very Advanced Solid Tumors. Canavan, ME, Wang X, Ascha MS, Miksad RA, Showalter TN, Calip GS, Gross CP, Adelson KB.. JAMA Oncol. 2024 Jul 1;10(7):887-895.

Antineoplastic Therapy Administration Safety Standards for Adult and Pediatric Oncology: ASCO-ONS Standards. Siegel RD, LeFebvre KB, Temin S, Evers A, Barbarotta L, Bowman RM, Chan A, Dougherty DW, Ganio M, Hunter B, Klein M, Miller TP, Mulvey TM, Ouzts A, Polovich M, Salazar-Abshire M, Stenstrup EZ, Sydenstricker CM, Tsai S, Oslen MM. JCO Oncol Pract. 2024 May 22:OP2400216.

Cathepsin B Nuclear Flux in a DNA-Guided “Antinuclear Missile” Cancer Therapy Fei Cao, Caroline Tang, Xiaoyong Chen, Zewei Tu, Ying Jin, Olivia M. Turk, Robert N. Nishimura, Allen Ebens, Valentina Dubljevic, James A. Campbell, Jiangbing Zhou and James E. Hansen ACS Central Science

A crisis in clinical research. Hong DS, LoRusso P, Sznol M. J Immunother Cancer. 2024 Jul 11;12(7):e008520.

Phase 2 Trial of the Farnesyltransferase Inhibitor Tipifarnib for Relapsed/Refractory Peripheral T Cell Lymphoma. Witzig TE, Sokol L, Kim WS, de la Cruz F, Martin Garcia-Sancho AM, Advani RH, Roncero Vidal JM, De Oña R, Marin-Niebla A, Izquierdo AR, Terol MJ MD, Domingo-Domenech E, Saunders A, Bendris N, Mackey J, Leoni M, Foss FM. Blood Adv. 2024 Jul 11

A single arm phase 2 clinical trial of YIV-906 with neoadjuvant concurrent chemo-radiation therapy in patients with locally advanced rectal cancer. Verma N, Johung KL, Kortmansky J, Zaheer W, Lacy J, Cecchini M, Stein S, Cheng YC, Lam W, Liu SH, Reddy V, Hochster H, Higgins SA. J Gastrointest Oncol. 2024 Jun 30

Providing 0.1 Full-Time Equivalent (FTE) Support to Fellowship Core Faculty Improves Faculty Involvement in Fellowship Education and Recruitment. Butt A, Christian J, Kress A, Lu BY, Hurwitz ME, Goldberg SB, Podoltsev NA, Gilkes L, Lee AI. J Cancer Educ. 2024 Jun

Surgical Outcomes and Utilization of Laparoscopic Versus Robotic Techniques for Elective Colectomy in Asian American and Native Hawaiian-Pacific Islanders (AAPI) Diagnosed With Colon Cancer. Ahuja V, Murthy SS, Leeds IL, Paredes LG, Su DG, Tsutsumi A, Perkal MF, King JT Jr. J Surg Res. 2024 Jul 30;302:40-46.

Modern Management of Gastric Neuroendocrine Neoplasms. Kunstman JW, Nagar A, Gibson J, Kunz PL. Curr Treat Options Oncol. 2024 Jul 31.

Causes of death and patterns of metastatic disease at the end of life for patients with advanced melanoma in the immunotherapy era. Lee DY, McNamara M, Yang A, Yaskolko M, Kluger H, Tran T, Olino K, Clune J, Sznol M, Ishizuka JJ. Pigment Cell Melanoma Res. 2024 Jul 28.

Incorporating prior information in gene expression network-based cancer heterogeneity analysis. Li R, Xu S, Li Y, Tang Z, Feng D, Cai J, Ma S. Biostatistics. 2024 Jul 29:kxae028.

CTHRC1+ fibroblasts and SPP1+ macrophages synergistically contribute to pro-tumorigenic tumor microenvironment in pancreatic ductal adenocarcinoma. Li E, Cheung HCZ, Ma S. Sci Rep. 2024 Jul 29;14(1):17412.

Acyl-CoA Synthetase Medium Chain Family Member 5 Mediated Fatty Acid Metabolism Dysregulation Promotes the Progression of Hepatocellular Carcinoma.Yang L, Pham K, Xi Y, Jiang S, Robertson K, Liu C. Am J Pathol. 2024 Jul 26:S0002-9440(24)00244-X.

Hypoxia-inducible factor 1alpha and vascular endothelial growth factor in Glioblastoma Multiforme: a systematic review going beyond pathologic implications. Vageli DP, Doukas PG, Goupou K, Benos AD, Astara K, Zacharouli K, Sotiriou S, Ioannou M. Oncol Res. 2024 Jul 17;32(8):1239-1256.

Asparagine synthetase and G-protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer. Lu L, Zhang Q, Aladelokun O, Berardi D, Shen X, Marin A, Garcia-Milian R, Roper J, Khan SA, Johnson CH. Int J Cancer. 2024 Jul 22.

Blood magnesium level and risk of hepatocellular carcinoma in a prospective liver cirrhosis cohort.Zhang X, Zhao L, Dai Q, Hou T, Danford CJ, Lai M, Zhang X. Cancer Epidemiol Biomarkers Prev. 2024 Jul 22.

Outcomes of repeat conventional transarterial chemoembolization in patients with liver metastases.Ghabili K, Windham-Herman AM, Konstantinidis M, Murali N, Borde T, Adam LC, Laage-Gaupp F, Lin M, Chapiro J, Georgiades C, Nezami N. Ann Hepatol. 2024 Jul 19:101529.

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.Valdez CN, Sánchez-Zuno GA, Osmani L, Ibrahim W, Galan A, Bacchiocchi A, Halaban R, Kulkarni RP, Kang I, Bucala R, Tran T. Oncotarget. 2024 Jul 19;15:507-520.

Sensitive detection of synthetic response to cancer immunotherapy driven by gene paralog pairs. Dong C, Zhang F, He E, Ren P, Verma N, Zhu X, Feng D, Zhao H, Chen S. bioRxiv [Preprint]. 2024 Jul 4:2024.07.02.601809.

Peripheral blood immune parameters, response, and adverse events after neoadjuvant chemotherapy plus durvalumab in early-stage triple-negative breast cancer. Foldi J, Blenman KRM, Marczyk M, Gunasekharan V, Polanska A, Gee R, Davis M, Kahn AM, Silber A, Pusztai L. Breast Cancer Res Treat. 2024 Jul 13.

Costs of care during chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell lymphomas. Di M, Potnis KC, Long JB, Isufi I, Foss F, Seropian S, Gross CP, Huntington SF. JNCI Cancer Spectr. 2024 Jul 1;8(4):pkae059.

JUNE

Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy.Diaz GM, Webb LT, Rabil MJ, Lokeshwar SD, Choksi AU, Leapman MS, Sprenkle PC. Curr Urol Rep. 2024 Oct;25(10):243-252. Epub 2024 Jun 19.

Association between pelvic lymph node dissection and survival among patients with prostate cancer treated with radical prostatectomy. Kim IE Jr, Wang AH, Corpuz GS, Sprenkle PC, Leapman MS, Brito JM, Renzulli J, Kim IY. Prostate Int. 2024 Jun;12(2):70-78.

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.Rosenberg JE, Mamtani R, Sonpavde GP, Loriot Y, Duran I, Lee JL, Matsubara N, Vulsteke C, Castellano D, Sridhar SS, Pappot H, Gurney H, Bedke J, van der Heijden MS, Galli L, Keam B, Masumori N, Meran J, O'Donnell PH, Park SH, Grande E, Sengeløv L, Uemura H, Skaltsa K, Campbell M, Matsangou M, Wu C, Hepp Z, McKay C, Powles T, Petrylak DP. Eur Urol. 2024 Jun;85(6):574-585.

Translation of Epigenetics in Cell-Free DNA Liquid Biopsy Technology and Precision Oncology. Tan WY, Nagabhyrava S, Ang-Olson O, Das P, Ladel L, Sailo B, He L, Sharma A, Ahuja N. Curr Issues Mol Biol. 2024 Jun 27;46(7):6533-6565.

Overexpression of Malat1 drives metastasis through inflammatory reprogramming of the tumor microenvironment. Martinez-Terroba E, Plasek-Hegde LM, Chiotakakos I, Li V, de Miguel FJ, Robles-Oteiza C, Tyagi A, Politi K, Zamudio JR, Dimitrova N. Sci Immunol. 2024 Jun 14;9(96):eadh5462.

Partial Hepatectomy and Ablation for Survival of Early-Stage Hepatocellular Carcinoma Patients: A Bayesian Emulation Analysis. Wang J, Im Y, Wang R, Ma S. Life (Basel). 2024 May 22;14(6):661.

High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC). Moutafi MK, Bates KM, Aung TN, Milian RG, Xirou V, Vathiotis IA, Gavrielatou N, Angelakis A, Schalper KA, Salichos L, Rimm DL. . J Immunother Cancer. 2024 Jun 10;12(6):e009039.

Adjuvant Trastuzumab Emtansine Versus Paclitaxel Plus Trastuzumab for Stage I Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: 5-Year Results and Correlative Analyses From ATEMPT. Tarantino P, Tayob N, Villacampa G, Dang C, Yardley DA, Isakoff SJ, Valero V, Faggen M, Mulvey T, Bose R, Weckstein D, Wolff AC, Reeder-Hayes K, Rugo HS, Ramaswamy B, Zuckerman D, Hart L, Gadi VK, Constantine M, Cheng K, Garrett AM, Marcom PK, Albain K, DeFusco P, Tung N, Ardman B, Nanda R, Jankowitz RC, Rimawi M, Abramson V, Pohlmann PR, Van Poznak C, Forero-Torres A, Liu MC, Ruddy KJ, Waks AG, DeMeo M, Burstein HJ, Partridge AH, Dell'Orto P, Russo L, Krause E, Newhouse DJ, Kurt BB, Mittendorf EA, Schneider B, Prat A, Winer EP, Krop IE, Tolaney SM; Consortium of the TBCRC Translational Investigators; TBCRC Translational Investigators. J Clin Oncol. 2024 Jun 27:JCO2302170.

Rare Drivers at Low Prevalence with High Cancer Effects in T-Cell and B-Cell Pediatric Acute Lymphoblastic Leukemia. Mandell JD, Diviti S, Xu M, Townsend JP. Int J Mol Sci. 2024 Jun 15;25(12):6589.

Surgical and Endoscopic Management of Clinical T1b Esophageal Cancer. Ayoade OF, Canavan ME, De Santis WP, Zhan PL, Boffa DJ. J Thorac Cardiovasc Surg. 2024 Jun 24:S0022-5223(24)00533-6.

In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy. Peng L, Renauer PA, Sferruzza G, Yang L, Zou Y, Fang Z, Park JJ, Chow RD, Zhang Y, Lin Q, Bai M, Sanchez A, Zhang Y, Lam SZ, Ye L, Chen S. Nat Biotechnol. 2024 Jun 25.

MAY

Trends and predictors of Quality of Life in lung cancer survivors. Bade BC, Zhao J, Li F, Tanoue L, Lazowski H, Alfano CM, Silvestri GA, Irwin ML. Lung Cancer. 2024 May;191:107793.

ASO Author Reflections: "Peace of Mind" After Surgery for Breast Cancer: Implications for Preference-Sensitive Shared Decision Making. Hamid SA, Schultz KS, Greenup RA. ASO Author Reflections: "Peace of Mind" After Surgery for Breast Cancer: Implications for Preference-Sensitive Shared Decision Making. Ann Surg Oncol. 2024 May;31(8):5209-5210.

Event-free survival by residual cancer burden with pembrolizumab in early-stage TNBC: exploratory analysis from KEYNOTE-522 Pusztai L, Denkert C, O'Shaughnessy J, Cortes J, Dent R, McArthur H, Kümmel S, Bergh J, Park YH, Hui R, Harbeck N, Takahashi M, Untch M, Fasching PA, Cardoso F, Zhu Y, Pan W, Tryfonidis K, Schmid P. Ann Oncol. 2024 May;35(5):429-436.

Digital Interventions to Support Lung Cancer Screening: A Systematic Review.Odole IP, Andersen M, Richman IB. Am J Prev Med. 2024 May;66(5):899-908. doi: 10.1016/j.amepre.2024.01.007. Epub 2024 Jan 20. PMID: 38246408.

Cancer and incarceration: a call for action. Richman IB, Gross CP, Wang EA. Lancet Oncol. 2024 May;25(5):530-531.

Promise and Perils of Large Language Models for Cancer Survivorship and Supportive Care. Bitterman DS, Downing A, Maués J, Lustberg M. J Clin Oncol. 2024 May 10;42(14):1607-1611.

Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomes. Saliby RM, Labaki C, Jammihal TR, Xie W, Sun M, Shah V, Saad E, Kane MH, Kashima S, Sadak K, El Zarif T, Poduval D, Motzer RJ, Powles T, Rini BI, Albiges L, Pal SK, McGregor BA, McKay RR, Signoretti S, Van Allen EM, Shukla SA, Choueiri TK, Braun DA. Cancer Cell. 2024 May 13;42(5):732-735.

TREM2 function in glioblastoma immune microenvironment: Can we distinguish reality from illusion? Ghosh S, Rothlin CV. Neuro Oncol. 2024 May 3;26(5):840-842

Approach to immunotherapy for HCC in the liver transplant population. Block PD, Strazzabosco M, Jaffe A. Clin Liver Dis (Hoboken). 2024 May 3;23(1):e0158.

An algorithm for standardization of tumor Infiltrating lymphocyte evaluation in head and neck cancers. Xirou V, Moutafi M, Bai Y, Nwe Aung T, Burela S, Liu M, Kimple RJ, Shabbir Ahmed F, Schultz B, Flieder D, Connolly DC, Psyrri A, Burtness B, Rimm DL. Oral Oncol. 2024 May;152:106750.

Event-free survival by residual cancer burden with pembrolizumab in early-stage TNBC: exploratory analysis from KEYNOTE-522. MAPusztai L, Denkert C, O'Shaughnessy J, Cortes J, Dent R, McArthur H, Kümmel S, Bergh J, Park YH, Hui R, Harbeck N, Takahashi M, Untch M, Fasching PA, Cardoso F, Zhu Y, Pan W, Tryfonidis K, Schmid P. Ann Oncol. 2024 May;35(5):429-436.

Exploring new perspectives in immunology. Medzhitov R, Iwasaki A. Cell. 2024 Apr 25;187(9):2079-2094. doi: 10.1016/j.cell.2024.03.038. PMID: 38670066.

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update. Gordan JD, Kennedy EB, Abou-Alfa GK, Beal E, Finn RS, Gade TP, Goff L, Gupta S, Guy J, Hoang HT, Iyer R, Jaiyesimi I, Jhawer M, Karippot A, Kaseb AO, Kelley RK, Kortmansky J, Leaf A, Remak WM, Sohal DPS, Taddei TH, Wilson Woods A, Yarchoan M, Rose MG. J Clin Oncol. 2024 May 20;42(15):1830-1850.

The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the Revisions of the T-Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Lung Cancer.Van Schil PE, Asamura H, Nishimura KK, Rami-Porta R, Kim YT, Bertoglio P, Cangir AK, Donington J, Fang W, Giroux DJ, Lievens Y, Liu H, Lyons G, Sakai S, Travis WD, Ugalde P, Jeffrey Yang CF, Yotsukura M, Detterbeck F; Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions. J Thorac Oncol. 2024 May;19(5):749-765.

So Now We Know-Reflections on the Extent of Resection for Stage I Lung Cancer. Detterbeck F, Ely S, Udelsman B, Blasberg J, Boffa D, Dhanasopon A, Mase V, Woodard G. Clin Lung Cancer. 2024 May;25(3):e113-e123.

The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the Revisions of the T-Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Lung Cancer. Van Schil PE, Asamura H, Nishimura KK, Rami-Porta R, Kim YT, Bertoglio P, Cangir AK, Donington J, Fang W, Giroux DJ, Lievens Y, Liu H, Lyons G, Sakai S, Travis WD, Ugalde P, Jeffrey Yang CF, Yotsukura M, Detterbeck F; Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions. J Thorac Oncol. 2024 May;19(5):749-765.

ARID1A in Gynecologic Precancers and Cancers. Morgan JE, Jaferi N, Shonibare Z, Huang GS. Reprod Sci. 2024 May 13.

Should the TNM Staging of NSCLC Evolve Beyond Anatomical Descriptors? Woodard GA, Dacic S. J Thorac Oncol. 2024 May;19(5):663-665

Digital Interventions to Support Lung Cancer Screening: A Systematic Review. Odole IP, Andersen M, Richman IB.. Am J Prev Med. 2024 May;66(5):899-908.

Peripheral Blood Extracellular Vesicle RNA Profiling: The Next Step in Cancer Liquid Biopsies. Hu R, Korutla L, Vallabhajosyula P. Ann Surg Oncol. 2024 May 16.

Melanoma tumour-infiltrating T-lymphocyte therapy heralds the era of cell-based immunotherapies for solid tumours. Talty R, Richmond R, Micevic G. Br J Dermatol. 2024 May 17;190(6):779-781.

Disparities in stage at diagnosis among breast cancer molecular subtypes in China. Zeng H, Wu S, Ma F, Ji JS, Lu L, Ran X, Shi J, Li D, An L, Zheng R, Zhang S, Chen W, Wei W, He Y, He J. Cancer Med. 2023 May;12(9):10865-10876.

The enduring neutrophil-stroma dance of multiple myeloma. Cerezo-Wallis D, Ballesteros I. Nat Immunol. 2024 May;25(5):731-732.

APRIL

Use of surveillance mammography among older patients with a history of breast cancer. Berger E, Long JB, Sheffrin M, Lindsay M, Richman IB. J Geriatr Oncol. 2024 Apr;15(3):101686.

Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity. Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris PC, Pearson MJ, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely MD, Zhang Y, Zhang J, Ji L, Flies DB, Liu L, Langermann S, LaRochelle WJ, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper KA, Sanmamed MF, Chen L. Sci Immunol. 2024 Apr 26;9(94):eadh2334.

Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring. Sun J, Esplugues E, Bort A, Cardelo MP, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Nat Metab. 2024 Apr;6(4):741-763.

De-Escalated Therapy and Early Treatment of Recurrences in HPV-Associated Head and Neck Cancer: The Potential for Biomarkers to Revolutionize Personalized Therapy. Yarbrough WG, Schrank TP, Burtness BA, Issaeva N. Viruses. 2024 Mar 29;16(4):536.

Real-world patterns and sequences of targeted therapy use in chronic lymphocytic leukemia and small lymphocytic lymphoma in the United States: a longitudinal study. Huntington SF, Cheng WY, Sarpong EM, Leng S, Farooqui MZH, Agu US, Catillon M, Lejeune D, Downes N, Matay L, Duh MS, De Nigris E. Leuk Lymphoma. 2024 May 2:1-11.

Immunometabolism of CD8⁺ T cell differentiation in cancer. Shi H, Chen S, Chi H. Trends Cancer. 2024 Apr 30:S2405-8033(24)00059-1. Epub ahead of print. PMID: 38693002.

Challenges in management of older patients with chronic myeloid leukemia. Stempel JM, Shallis RM, Wong R, Podoltsev NA. Leuk Lymphoma. 2024 Apr 23:1-14.

Area Vulnerability and Disparities in Therapy for Patients With Metastatic Renal Cell Carcinoma. Rahman SN, Long JB, Westvold SJ, Leapman MS, Spees LP, Hurwitz ME, McManus HD, Gross CP, Wheeler SB, Dinan MA JAMA Netw Open. 2024 Apr 1;7(4):e248747.

Cost-effectiveness of adding quizartinib to induction chemotherapy for patients with FLT3-mutant acute myeloid leukemia. Bewersdorf JP, Patel KK, Shallis RM, Podoltsev NA, Kewan T, Stempel J, Mendez L, Stahl M, Stein EM, Huntington SF, Goshua G, Zeidan AM. Leuk Lymphoma. 2024 Apr 22:1-9.

Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation. Xin T, Gallini S, Wei H, Gonzalez DG, Matte-Martone C, Machida H, Fujiwara H, Pasolli HA, Suozzi KC, Gonzalez LE, Regot S, Greco V. Nat Cell Biol. 2024 Apr 30.

Trends and predictors of Quality of Life in lung cancer survivors. Bade BC, Zhao J, Li F, Tanoue L, Lazowski H, Alfano CM, Silvestri GA, Irwin ML. Lung Cancer. 2024 Apr 16;191:107793.

A retrospective cohort study describing chemotherapy-induced peripheral neuropathy in Non-Hodgkin lymphoma patients treated with EPOCH ± R: does HIV status matter? McNally GA, Aossey CM, Wiczer T, Sinnott LT, Lustberg M, Baiocchi RA, Lustberg M. Leuk Lymphoma. 2024 Apr 22:1-7.

MARCH

A Randomized, Noninferiority Trial of a Pretest, Patient-Driven Genetic Education Webtool Versus Genetic Counseling for Prostate Cancer Germline Testing. Loeb S, Keith SW, Cheng HH, Leader AE, Gross L, Sanchez Nolasco T, Byrne N, Hartman R, Brown LH, Pieczonka CM, Gomella LG, Kelly WK, Lallas CD, Handley N, Mille PJ, Mark JR, Brown GA, Chopra S, McClellan A, Wise DR, Hollifield L, Giri VN. JCO Precis Oncol. 2024 Mar;8:e2300552.

Estimating Breast Cancer Overdiagnosis After Screening Mammography Among Older Women in the United States. Richman IB, Gross CP. Ann Intern Med. 2024 Mar;177(3):403-404.

De novo-designed transmembrane proteins bind and regulate a cytokine receptor. Mravic M, He L, Kratochvil HT, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF. Nat Chem Biol. 2024 Mar 13. doi: 10.1038/s41589-024-01562-z. Epub ahead of print.

Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial. Puklin LS, Ferrucci LM, Harrigan M, McGowan C, Zupa M, Cartmel B, Li FY, Ligibel JA, Spiegelman D, Sharifi M, Sanft T, Irwin ML. Cancer. 2024 Mar 12. doi: 10.1002/cncr.35280. Epub ahead of print.

Impact of ¹⁸F-FDG PET Intensity Normalization on Radiomic Features of Oropharyngeal Squamous Cell Carcinomas and Machine Learning-Generated Biomarkers. Haider SP, Zeevi T, Sharaf K, Gross M, Mahajan A, Kann BH, Judson BL, Prasad ML, Burtness B, Aboian M, Canis M, Reichel CA, Baumeister P, Payabvash S. J Nucl Med. 2024 Mar 21:jnumed.123.266637. Online ahead of print.

Oncology hospitalist impact on hospice utilization. Prsic E, Morris JC, Adelson KB, Parker NA, Gombos EA, Kottarathara MJ, Novosel M, Castillo L, Gould Rothberg BE. Cancer. 2023 Dec 1;129(23):3797-3804.

A Comparison Between In-Person and Virtual Communication Skills OSCE for Medical Students. Choi A, Murtha TD, Morrison LJ, Talwalkar JS. J Med Educ Curric Dev. 2024 Mar 25;11:23821205241241375.

The Right Dose: Results of a Patient Advocate-Led Survey of Individuals With Metastatic Breast Cancer Regarding Treatment-Related Side Effects and Views About Dosage Assessment to Optimize Quality of Life. Loeser A, Kim JS, Peppercorn J, Burkard ME, Niemierko A, Juric D, Kalinsky K, Rugo H, Glenn L, Hodgdon C, Maues J, Johnson S, Padron N, Parekh K, Lustberg M, Bardia A. JCO Oncol Pract. 2024 Mar 22:OP2300539. Epub ahead of print.

Impact of the Breast Cancer Index for Extended Endocrine Decision-Making: First Results of the Prospective BCI Registry Study. Sanft TB, Wong J, O'Neal B, Siuliukina N, Jankowitz RC, Pegram MD, Fox JR, Zhang Y, Treuner K, O'Shaughnessy JA. J Natl Compr Canc Netw. 2024 Mar 4;22(2):99-107.

Renovating the Commission on Cancer's Quality Measure Portfolio. Boffa DJ, Lum SS, Palis B, McCabe R, Park KU, Siddiqui MM, Facktor M, Mullet T, Nelson H. Ann Surg. 2024 Mar 28. Online ahead of print.

EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling. Hu Z, Chen PH, Li W, Krone M, Zheng S, Saarbach J, Velasco IU, Hines J, Liu Y, Crews CM. Sci Adv. 2024 Mar 29;10(13):eadj7251.

How Far We've Come. Sznol M, Weber JS. Cancer J. 2024 Mar-Apr 01;30(2):47.

Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma. Su DG, Schoenfeld DA, Ibrahim W, Cabrejo R, Djureinovic D, Baumann R, Rimm DL, Khan SA, Halaban R, Kluger HM, Olino K, Galan A, Clune J. J Immunother Cancer. 2024 Mar 21;12(3):e008646.

Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape. Boddu PC, Gupta AK, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Mol Cell. 2024 Mar 22:S1097-2765(24)00175-8. Online ahead of print

Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group. Tabor JK, Dincer A, O'Brien J, Lei H, Vetsa S, Vasandani S, Jalal MI, Yalcin K, Morales-Valero SF, Marianayagam N, Alanya H, Elsamadicy AA, Millares Chavez MA, Aguilera SM, Mishra-Gorur K, McGuone D, Fulbright RK, Jin L, Erson-Omay EZ, Günel M, Moliterno J. J Neurosurg. 2024 Mar 22:1-9.

Clinical Outcomes Among Immunotherapy-Treated Patients With Primary Cardiac Soft Tissue Sarcomas: A Multicenter Retrospective Study. Nassar AH, El-Am E, Denu R, Abou Alaiwi S, El Zarif T, Macaron W, Abdel-Wahab N, Desai A, Smith C, Parikh K, Abbasi M, Bou Farhat E, Williams JM, Collins JD, Al-Hader A, McKay RR, Malvar C, Sabra M, Zhong C, El Alam R, Chehab O, Lima J, Phan M, Dalla Pria HF, Trevino A, Neilan TG, Kwan JM, Ravi V, Deshpande H, Demetri G, Choueiri TK, Naqash AR. JACC CardioOncol. 2024 Jan 16;6(1):71-79.

Clinical activity, pharmacokinetics, and pharmacodynamics of oral hypomethylating agents for myelodysplastic syndromes/neoplasms and acute myeloid leukemia: A multidisciplinary review. Haumschild R, Kennerly-Shah J, Barbarotta L, Zeidan AM. J Oncol Pharm Pract. 2024 Mar 21:10781552241238979.

Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer. Yu JB, DeStephano DM, Jeffers B, Horowitz DP, Soulos PR, Gross CP, Cheng SK. J Clin Oncol. 2024 Mar 20:JCO2301604.

JANUARY

JAMA Oncology kicked off 2024 for YCC with Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US. The study’s senior author, Dr. Sajid Khan, is section chief of hepato-pancreato-biliary (HPB) and mixed tumors at Yale School of Medicine. The study drew headlines on OncLive, Medscape, the Cancer Network and others and a JAMA Oncology podcast.

In other publication news, a chance encounter at the recent Stand Up To Cancer (SU2C) meeting in San Diego led to Yale’s Alessandro Santin, MD, learning he and the gynecologic oncology research/clinical team had been named in an article in a July 2023 issue of Medicine. The article, Bibliometric and visualized analysis of the top-100 highly cited articles on immunotherapy for endometrial cancer, concluded: “The attention of researchers from different countries to EC immunotherapy, especially immunosuppressants, has brought a breakthrough in this field.” Yale was singled out for ranking first, followed by MSKCC, for citations in endometrial cancer immunotherapy research worldwide in the period studied.

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth. Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna RS, Traina KA, Robles-Oteíza C, Ayeni D, Kwong EM, Levy S, Globig AM, Nobari MM, Cheng GZ, Leibel SL, Homer RJ, Shaw RJ, Metallo CM, Politi K, Kaech SM. Cancer Discov. 2024 Jan 25:OF1-OF22

Neutrophils in Physiology and Pathology Aroca-Crevillén A, Vicanolo T, Ovadia S, Hidalgo A. Annu Rev Pathol. 2024 Jan 24;19:227-259

Transmembrane pH gradient imaging in rodent glioma models Mishra SK, Santana JG, Mihailovic J, Hyder F, Coman D. NMR Biomed. 2024 Jan 23:e5102

Cell surface RNAs control neutrophil recruitment Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan SA, Kumar P, Hidalgo A, Wu D, Lu J. Cell. 2024 Jan 17:S0092-8674(23)01443-5

Consolidation Osimertinib versus Durvalumab versus Observation following Concurrent Chemoradiation in Unresectable EGFR-Mutant Non-Small-Cell Lung Cancer: A Multicenter Retrospective Cohort Study. Nassar AH, Kim SY, Aredo JV, Feng J, Shepherd F, Xu C, Kaldas D, Gray JE, Dilling TJ, Neal JW, Wakelee HA, Liu Y, Lin SH, Abuali T, Amini A, Nie Y, Patil T, Lobachov A, Bar J, Fitzgerald B, Fujiwara Y, Marron TU, Thummalapalli R, Yu H, Owen DH, Sharp J, Farid S, Rocha P, Arriola E, D'Aiello A, Cheng H, Whitaker R, Parikh K, Ashara Y, Chen L, Sankar K, Harris JP, Nagasaka M, Ayanambakkam A, Manana AI, Ragavan M, Lin JJ, Piotrowska Z, Wilgucki M, Reuss J, Luders H, Grohe C, Espinar JB, Feiner E, Punekar SR, Gupta S, Leal T, Kwiatkowski DJ, Mak RH, Adib E, Naqash AR, Goldberg SB. J Thorac Oncol. 2024 Jan 24:S1556-0864(24)00032-7.

Sensitizing the Efficiency of ICIs by Neoantigen mRNA Vaccines for HCC Treatment Han R, Wang Y, Lu L. Pharmaceutics. 2023 Dec 29;16(1):59

Endoscopic Ultrasound in Cancer Staging Aslanian HR, Muniraj T, Nagar A, Parsons D. Gastrointest Endosc Clin N Am. 2024 Jan; 34(1):37-49.

Multi-Institutional Outcomes of Dorsal Onlay Buccal Mucosal Graft Urethroplasty in Patients With Postprostatectomy, Postradiation Anastomotic Stenosis. Sterling J, Simhan J, Flynn BJ, Rusilko P, Franca WA, Ramirez EA, Angulo JC, Martins FE, Patel HV, Higgins M, Swerdloff D, Nikolavsky D. J Urol. 2024 Jan 26:101097JU0000000000003848

Evaluating an Enterprise-Wide Initiative to enhance healthcare coordination for rural women Veterans using the RE-AIM framework. Relyea MR, Kinney RL, DeRycke EC, Haskell S, Mattocks KM, Bastian LA. Front Health Serv. 2024 Jan 12;3:1237701

Medical Physics Training and Education: Learning From the Past and Looking to the Future. Bertholet J, Al Hallaq H, Toma-Dasu I, Ingledew PA, Carlson DJ. Int J Radiat Oncol Biol Phys. 2023 Dec 1;117(5):1039-1044.

Precision Oncology in Gastrointestinal and Colorectal Cancer Surgery H. G. McDonald, D. M. Kerekes, J. Kim and S. A. Khan. Surgical Oncology Clinics of North America 2024

Randomized placebo-controlled, double-blind clinical trial of nanoemulsion curcumin in women with aromatase inhibitor-induced arthropathy: an Alliance/NCORP pilot trial. Lustberg M, Fan-Havard P, Wong FL, Hill K, Phelps MA, Herrera KW, Tsai NC, Synold T, Feng Y, Kalu C, Sedrak MS, Yee LD. Breast Cancer Res Treat. 2024 Jan 27.

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