2024
Prediction of craving across studies: A commentary on conceptual and methodological considerations when using data-driven methods
Antons S, Yip S, Lacadie C, Dadashkarimi J, Scheinost D, Brand M, Potenza M. Prediction of craving across studies: A commentary on conceptual and methodological considerations when using data-driven methods. Journal Of Behavioral Addictions 2024, 13: 695-701. PMID: 39356557, PMCID: PMC11457034, DOI: 10.1556/2006.2024.00050.Peer-Reviewed Original ResearchConceptsAddictive behaviorsDisorders due to addictive behaviorsConnectome-based predictive modelingPrediction of cravingInvestigate neural mechanismsSubstance use disordersNeural mechanismsCravingSubstance useMethodological considerationsDisordersMethodological featuresBehaviorConceptualizationCommentaryStudyFindingsSubstancesNeural correlates of altered emotional responsivity to infant stimuli in mothers who use substances
McCurdy L, Yip S, Worhunsky P, Zhai Z, Kim S, Strathearn L, Potenza M, Mayes L, Rutherford H. Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances. Journal Of Psychiatric Research 2024, 171: 126-133. PMID: 38277872, PMCID: PMC10922955, DOI: 10.1016/j.jpsychires.2024.01.024.Peer-Reviewed Original ResearchConceptsResponses to infant stimuliInfant stimuliMaternal behaviorAffective processesBrain regionsPsychological processesEmotional responsesFunctional magnetic resonance imagingPotential neural targetsInfant emotional expressionsMaternal emotional responsivenessSubstance-use statusAssociated with difficultiesSocial-emotional developmentInfant social-emotional developmentMaternal substance useInfant facesCognitive processesImprove child outcomesEmotional expressionEmotional intensityNeural targetsSubstance useGroups of mothersChild outcomes
2023
Neural correlates of negative life events and their relationships with alcohol and cannabis use initiation
Zhao Y, Potenza M, Tapert S, Paulus M. Neural correlates of negative life events and their relationships with alcohol and cannabis use initiation. Dialogues In Clinical Neuroscience 2023, 25: 112-121. PMID: 37916739, PMCID: PMC10623894, DOI: 10.1080/19585969.2023.2252437.Peer-Reviewed Original ResearchConceptsNegative life eventsCannabis initiationGreater cortical thicknessCaudate gray matter volumeGray matter volumeDose-response relationshipOdds of alcoholLife eventsInitiation of alcoholSubstance Use InitiationCortical thicknessSubstance-naïveSuperior temporal sulcusNeural pathwaysCannabis useBrain structuresAlcohol useUse initiationAlcohol initiationSubstance use trajectoriesPoor academic performanceTemporal sulcusNeural mechanismsCannabisLinear regression modelsDiagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder
Zakiniaeiz Y, Lacadie C, Macdonald-Gagnon G, DeVito E, Potenza M. Diagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder. Drug And Alcohol Dependence 2023, 251: 110962. PMID: 37716288, PMCID: PMC10557108, DOI: 10.1016/j.drugalcdep.2023.110962.Peer-Reviewed Original ResearchConceptsCocaine use disorderCognitive controlStroop performanceIntrinsic connectivityStroop task performanceFMRI Stroop taskDiagnostic groupsUse disordersDiagnostic group differencesMain effectHealthy comparison subjectsStroop effectStroop taskBehavioral resultsTask performanceFrontal gyrusIntrinsic connectivity distributionPrefrontal cortexAuditory areasGroup differencesBrain connectivityCingulate gyrusStroopBehavioral differencesHC groupNeural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders
Mestre-Bach G, Potenza M. Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders. Dialogues In Clinical Neuroscience 2023, 25: 75-91. PMID: 37594217, PMCID: PMC10444012, DOI: 10.1080/19585969.2023.2242359.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNeural mechanismsAddictive disordersPotential neural mechanismsTreatment development effortsInternet gaming disorderBrain processesSubstance use disordersAdvanced analytic approachesGaming disorderImpulse controlTreatment developmentUse disordersPsychiatric conditionsExtant dataTreatment utilityAddictionDisordersAnalytic approachTreatment outcomesNarrative reviewIntervention administrationMedication challengePresent reviewMain modelsContextRelationships of in vivo brain norepinephrine transporter and age, BMI, and gender
Koohsari S, Sadabad F, Pittman B, Gallezot J, Carson R, van Dyck C, Li C, Potenza M, Matuskey D. Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender. Synapse 2023, 77: e22279. PMID: 37382240, PMCID: PMC10416616, DOI: 10.1002/syn.22279.Peer-Reviewed Original ResearchConceptsBody mass indexMultilinear reference tissue model 2Gender-related differencesBrain norepinephrine transportersNorepinephrine transporterAge-related declineStructural MR scansBrain regionsReference tissue model 2Mass indexRaphe nucleusLocus coeruleusOccipital cortexBMI relationshipHealthy adultsHigh-resolution research tomographAvailable radiotracersHealthy participantsMR scansAgeAnatomic templateReference regionNegative associationNet availabilityPotential ageConnectome-based prediction of craving in gambling disorder and cocaine use disorder
Antons S, Yip S, Lacadie C, Dadashkarimi J, Scheinost D, Brand M, Potenza M. Connectome-based prediction of craving in gambling disorder and cocaine use disorder. Dialogues In Clinical Neuroscience 2023, 25: 33-42. PMID: 37190759, PMCID: PMC10190201, DOI: 10.1080/19585969.2023.2208586.Peer-Reviewed Original ResearchConceptsCocaine use disorderGambling disorderBehavioral addictionsCue-reactivity taskComponents of memoryGeneral neural mechanismCommon neural networkFunctional magnetic resonanceMedial frontal regionsDefault mode networkFeatures of addictionAutobiographical memoryValence ratingsMeta-analytic dataPrefrontal regionsNeural mechanismsPrefrontal cortexFronto-parietalFrontal regionsMotor imageryMotor/Diverse sampleLimbic networkNeural connectivityCravingTransdiagnostic Connectome-Based Prediction of Craving
Garrison K, Sinha R, Potenza M, Gao S, Liang Q, Lacadie C, Scheinost D. Transdiagnostic Connectome-Based Prediction of Craving. American Journal Of Psychiatry 2023, 180: 445-453. PMID: 36987598, DOI: 10.1176/appi.ajp.21121207.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingImagery conditionFunctional connectomeSelf-reported cravingStudy of motivationDefault mode networkFunctional connectivity dataIndependent samplesKey phenomenological featuresNeural signaturesTransdiagnostic sampleTransdiagnostic perspectiveMode networkMotivated behaviorCentral constructAddictive disordersHuman behaviorConnectivity dataPhenomenological featuresStrongest predictorCravingTaskSubstance use-related disordersConnectomeIndividualsYouth Screen Media Activity Patterns and Associations With Behavioral Developmental Measures and Resting-state Brain Functional Connectivity
Song K, Zhang J, Zhou N, Fu Y, Zou B, Xu L, Wang Z, Li X, Zhao Y, Potenza M, Fang X, Zhang J. Youth Screen Media Activity Patterns and Associations With Behavioral Developmental Measures and Resting-state Brain Functional Connectivity. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: 1051-1063. PMID: 36963562, PMCID: PMC10509312, DOI: 10.1016/j.jaac.2023.02.014.Peer-Reviewed Original ResearchConceptsBrain functional connectivityResting-state brain functional connectivityDevelopmental measuresFunctional connectivityHuman participantsTotal behavioral problemsPsychotic-like experiencesPoorer neurocognitive performanceHuman Connectome ProjectCognitive processesAdolescent brainYouth developmentABCD dataHigh impulsivityNeurocognitive performanceBrain measuresPunishment/Behavioral problemsConnectome ProjectLate childhoodLinear mixed effectsBrain areasYouth lifeIndependent samplesParticipantsBrain structural co-development is associated with internalizing symptoms two years later in the ABCD cohort
Zhao Y, Paulus M, Potenza M. Brain structural co-development is associated with internalizing symptoms two years later in the ABCD cohort. Journal Of Behavioral Addictions 2023, 12: 80-93. PMID: 36940096, PMCID: PMC10260217, DOI: 10.1556/2006.2023.00006.Peer-Reviewed Original ResearchConceptsScreen media activitiesGray matter volumeInternalizing problemsTwo yearsSymptoms two yearsTwo-year followInferior temporal regionsCortical thickness measuresHours/dayLongitudinal brain imagingInternalizing psychopathologyABCD cohortSmall effect sizesFuture internalizing problemsInternalizing behaviorsExternalizing psychopathologyInferior parietalMediation analysisBrain patternsBrain featuresGreater riskLinear mixed-effects modelsTemporal regionsAge 9Thickness measuresIndependent component analysis for internet gaming disorder
Mestre-Bach G, Granero R, Fernández-Aranda F, Jiménez-Murcia S, Potenza M. Independent component analysis for internet gaming disorder. Dialogues In Clinical Neuroscience 2023, 25: 14-23. PMID: 36817972, PMCID: PMC9930851, DOI: 10.1080/19585969.2023.2168135.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPotential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions
Mestre-Bach G, Potenza M. Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions. Nutrients 2023, 15: 827. PMID: 36839185, PMCID: PMC9962023, DOI: 10.3390/nu15040827.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInternet gaming disorderGambling disorderVentral striatumBehavioral addictionsBinge Eating DisorderReward processingEating DisordersGaming disorderReward systemTreatment implicationsBrain regionsBrain changesTreatment-related changesAddictionDisordersBingePotential biological markersPossible biomarkersBiological markersMore evidenceSpecific roleProcessingInterventionImplicationsCircuitry
2022
Neural activations to loss anticipation mediates the association between difficulties in emotion regulation and screen media activities among early adolescent youth: A moderating role for depression
Zhang J, Zhou N, Song K, Zou B, Xu L, Fu Y, Geng X, Wang Z, Li X, Potenza M, Nan Y, Zhang J. Neural activations to loss anticipation mediates the association between difficulties in emotion regulation and screen media activities among early adolescent youth: A moderating role for depression. Developmental Cognitive Neuroscience 2022, 58: 101186. PMID: 36516611, PMCID: PMC9764194, DOI: 10.1016/j.dcn.2022.101186.Peer-Reviewed Original ResearchConceptsReward/loss processingDorsolateral prefrontal cortexProcessing of emotionsScreen media activitiesAnterior insulaLoss processingEmotion regulationBrain activationRight dorsolateral prefrontal cortexMonetary incentive delay taskDepressive symptomsNegative emotional situationsEarly adolescent youthIncentive delay taskNegative emotional statesLeft anterior insulaPotential mediating factorsAI activationNeural correlatesFMRI scanningDelay taskEmotional situationsEmotional statesLoss anticipationMediation modelDisrupted network integration and segregation involving the default mode network in autism spectrum disorder
Yang B, Wang M, Zhou W, Wang X, Chen S, Potenza M, Yuan L, Dong G. Disrupted network integration and segregation involving the default mode network in autism spectrum disorder. Journal Of Affective Disorders 2022, 323: 309-319. PMID: 36455716, DOI: 10.1016/j.jad.2022.11.083.Peer-Reviewed Original ResearchBayesian network mediation analysis with application to the brain functional connectome
Zhao Y, Chen T, Cai J, Lichenstein S, Potenza M, Yip S. Bayesian network mediation analysis with application to the brain functional connectome. Statistics In Medicine 2022, 41: 3991-4005. PMID: 35795965, PMCID: PMC10131252, DOI: 10.1002/sim.9488.Peer-Reviewed Original ResearchConceptsStochastic block modelBayesian paradigmBrain functional connectomeBlock modelConnectivity weightsFunctional connectomeNetwork measurementsEffect componentApproach applicationBlock allocationOpioid abstinenceAnalytic approachNetwork neurosciencePractical illustrationTherapeutic interventionsMediation analysisNeural circuitsNetwork structureBrain functioningMediatorsFunctional networksFeature selectionApplicationsModelNetwork
2019
Neural Correlates of Personalized Spiritual Experiences
Miller L, Balodis IM, McClintock CH, Xu J, Lacadie CM, Sinha R, Potenza MN. Neural Correlates of Personalized Spiritual Experiences. Cerebral Cortex 2019, 29: 2331-2338. PMID: 29846531, PMCID: PMC6519691, DOI: 10.1093/cercor/bhy102.Peer-Reviewed Original ResearchConceptsInferior parietal lobuleNeural correlatesNeural mechanismsSpiritual experiencesLeft inferior parietal lobuleUnderlying neural mechanismsPerceptual processingEmotional processingSense of unionBrain correlatesParietal lobuleStress cuesCuesCorrelatesReduced activitySelfExperienceHuman beingsProcessingMedial thalamusTaskSpiritual conditionSenseDifferent traditionsCaudate
2018
fMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals
DeVito EE, Kober H, Carroll KM, Potenza MN. fMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals. Addictive Behaviors 2018, 89: 10-14. PMID: 30240978, PMCID: PMC6374034, DOI: 10.1016/j.addbeh.2018.09.005.Peer-Reviewed Original ResearchConceptsCocaine use disorderStroop effectBehavioral treatmentComputer-based cognitive behavioral therapyColor-word Stroop taskCognitive neuroscience methodsCognitive behavioral therapyCocaine-dependent individualsCocaine abstinenceCognitive controlStroop taskNeuroscience methodsMethadone-maintained individualsTreatment abstinenceLingual gyrusStroopCingulate gyrusUse disordersCocaine usersTreatment mechanismsAbstinenceBetter treatment outcomesPreliminary findingsGyrusParticipantsGender-related functional connectivity and craving during gaming and immediate abstinence during a mandatory break: Implications for development and progression of internet gaming disorder
Dong G, Wang Z, Wang Y, Du X, Potenza MN. Gender-related functional connectivity and craving during gaming and immediate abstinence during a mandatory break: Implications for development and progression of internet gaming disorder. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2018, 88: 1-10. PMID: 29684536, DOI: 10.1016/j.pnpbp.2018.04.009.Peer-Reviewed Original Research
2017
White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine
Morie KP, Yip SW, Zhai ZW, Xu J, Hamilton KR, Sinha R, Mayes LC, Potenza MN. White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine. Drug And Alcohol Dependence 2017, 174: 23-29. PMID: 28292689, PMCID: PMC5555052, DOI: 10.1016/j.drugalcdep.2017.01.011.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureSuperior longitudinal fasciculusPCE adolescentsCrossing-fiber modelsGroup differencesWhole-brain investigationNon-exposed youthWhole-brain analysisSignificant group differencesAltered white matter developmentLeft superior longitudinal fasciculusRisk-taking behaviorNeurobiological underpinningsWhite matter developmentWhite matter microstructureSubstance useWhite matter differencesWhite matter regionsAdolescentsDiffusion-weighted imaging dataCocaine exposureLongitudinal cohortBilateral cingulumCorpus callosumROI analysis