2019
1346-P: Longitudinal Evaluation of Cognitive Functioning in Young Children with Type 1 Diabetes: Persistent Effects on IQ and Vocabulary
WEINZIMER S, AMBROSINO J, CATO A, JO B, ENGLERT K, WHITE N, ARBELAEZ A, HERSHEY T, FOX L, TSALIKIAN E, TANSEY M, BUCKINGHAM B, AYE T, WILSON D, TAMBORLANE W, REISS A, MAURAS N. 1346-P: Longitudinal Evaluation of Cognitive Functioning in Young Children with Type 1 Diabetes: Persistent Effects on IQ and Vocabulary. Diabetes 2019, 68 DOI: 10.2337/db19-1346-p.Peer-Reviewed Original ResearchSpouse/partnerFull Scale IQVerbal IQSignificant cognitive differencesYoung childrenResearch supportCognitive differencesCognitive functioningCognitive dataProcessing speedParental IQNeuropsychological testingIQBrain maturationLower scoresSelfVocabularyHuman developmentChildrenCritical periodLongitudinal evaluationMixed effectsCognitionPartnersVIQ
2016
Compensatory Hyperconnectivity in Developing Brains of Young Children With Type 1 Diabetes
Saggar M, Tsalikian E, Mauras N, Mazaika P, White NH, Weinzimer S, Buckingham B, Hershey T, Reiss AL. Compensatory Hyperconnectivity in Developing Brains of Young Children With Type 1 Diabetes. Diabetes 2016, 66: 754-762. PMID: 27702833, PMCID: PMC5319714, DOI: 10.2337/db16-0414.Peer-Reviewed Original ResearchConceptsControl subjectsIntrinsic connectivityAge-matched control subjectsYoung childrenBrain intrinsic connectivityResting-state functional MRI dataType 1 diabetesSeed-based analysisCognitive functioningBlood glucoseSustained dysregulationOverall group differencesLarge multisite studyT1DYounger ageFunctional MRI dataCognitive deficitsType 1Cognitive functionObserved positive associationDiabetesMultisite studyCompensatory roleGroup differencesBrain