2013
Attacking Breast Cancer at the Preinvasion Stage by Targeting Autophagy
Espina V, Wysolmerski J, Edmiston K, Liotta LA. Attacking Breast Cancer at the Preinvasion Stage by Targeting Autophagy. Women's Health 2013, 9: 157-170. PMID: 23477322, PMCID: PMC3779365, DOI: 10.2217/whe.13.5.BooksConceptsBreast cancerBreast cancer stem-like cellsCancer stem-like cellsBreast carcinoma cellsStem-like cellsDuctal carcinomaPreinvasive carcinomaPreinvasive neoplasmsClinical trialsIntracellular calciumSevere hypoxicTherapeutic strategiesNeoplastic cellsCarcinoma cellsMetabolic stressCarcinomaTherapyCancerCellsSurvival mechanismAutophagyNeoplasmsTrialsHypoxic
1996
Parathyroid hormone-related protein gene expression in human squamous carcinoma cells is repressed by mutant isoforms of p53.
Foley J, Wysolmerski JJ, Broadus AE, Philbrick WM. Parathyroid hormone-related protein gene expression in human squamous carcinoma cells is repressed by mutant isoforms of p53. Cancer Research 1996, 56: 4056-62. PMID: 8752179.Peer-Reviewed Original ResearchMeSH KeywordsAdenovirus E1B ProteinsCarcinoma, Squamous CellGene ExpressionGenes, p53Genes, ReporterHumansIsomerismKeratinocytesMutationParathyroid Hormone-Related ProteinPromoter Regions, GeneticProtein BiosynthesisProteinsRNA, MessengerTATA BoxTransfectionTumor Cells, CulturedTumor Suppressor Protein p53ConceptsHormone-related protein gene expressionPTHrP expression levelsSquamous carcinoma linesHormone-related proteinNormal secretory productP53 functional statusSquamous carcinoma cellsPTHrP gene expressionHuman squamous carcinoma cellsMutant p53 isoformsHumoral hypercalcemiaSquamous carcinomaFunctional statusPTHrP expressionPTHrP mRNASquamous epitheliumEndogenous mutant p53Mutant isoformsP53 isoformsCarcinoma linesWild-type p53Carcinoma cellsGene expressionCodon 248PTHrP transcripts