2022
Effect of Implementation Facilitation to Promote Adoption of Medications for Addiction Treatment in US HIV Clinics
Edelman EJ, Gan G, Dziura J, Esserman D, Porter E, Becker WC, Chan PA, Cornman DH, Helfrich CD, Reynolds J, Yager JE, Morford KL, Muvvala SB, Fiellin DA. Effect of Implementation Facilitation to Promote Adoption of Medications for Addiction Treatment in US HIV Clinics. JAMA Network Open 2022, 5: e2236904. PMID: 36251291, PMCID: PMC9577676, DOI: 10.1001/jamanetworkopen.2022.36904.Peer-Reviewed Original ResearchConceptsTobacco use disorderHIV clinicOpioid use disorderUse disordersAlcohol use disorderAddiction treatmentControl periodImplementation facilitationAdoption of medicationsMulticomponent implementation strategyProvision of MOUDUS HIV clinicsMaintenance periodElectronic health record dataHealth record dataEvaluation periodAdult patientsMean ageClinical trialsMAIN OUTCOMEClinicMOUDPatientsDisordersPatient incentives
2021
Direct observation in a large-scale randomized trial of parent training in children with autism spectrum disorder and disruptive behavior
Swiezy N, Smith T, Johnson CR, Bearss K, Lecavalier L, Drill R, Warner D, Deng Y, Xu Y, Dziura J, Handen B, Scahill L. Direct observation in a large-scale randomized trial of parent training in children with autism spectrum disorder and disruptive behavior. Research In Autism Spectrum Disorders 2021, 89: 101879. PMID: 34950225, PMCID: PMC8691726, DOI: 10.1016/j.rasd.2021.101879.Peer-Reviewed Original ResearchAutism spectrum disorderDisruptive behaviorParent trainingSpectrum disorderParent ratingsParentchild interactionChild behaviorObservation measuresResource-intensive effortsChild participantsParent educationYoung childrenSame measuresLaboratory settingChildrenSOAP dataPrimary measureMeasuresModerate levelsTrainingPrimary purposeDisordersStudy entry criteriaBehaviorOutcome measures
2017
An Interventionist Adherence Scale for a Specialized Brief Negotiation Interview Focused on Treatment Engagement for Opioid use Disorders
Pantalon MV, Dziura J, Li FY, Owens PH, O'Connor PG, D'Onofrio G. An Interventionist Adherence Scale for a Specialized Brief Negotiation Interview Focused on Treatment Engagement for Opioid use Disorders. Substance Abuse 2017, 38: 191-199. PMID: 28398192, PMCID: PMC7222694, DOI: 10.1080/08897077.2017.1294548.Peer-Reviewed Original ResearchConceptsTreatment engagementPsychometric propertiesUse disordersPredictive validityBrief Negotiation InterviewGood internal consistencyEnhance motivationBrief interventionDiscriminant validityFair predictive validitySkill performanceValid measureInternal consistencyExcellent interrater reliabilityControl encountersBASFactor itemsMotivationEngagementDisordersCritical actionsOpioid use disorderValidityRatersItems
2015
Extended-Release Guanfacine for Hyperactivity in Children With Autism Spectrum Disorder
Scahill L, McCracken JT, King BH, Rockhill C, Shah B, Politte L, Sanders R, Minjarez M, Cowen J, Mullett J, Page C, Ward D, Deng Y, Loo S, Dziura J, McDougle CJ. Extended-Release Guanfacine for Hyperactivity in Children With Autism Spectrum Disorder. American Journal Of Psychiatry 2015, 172: 1197-1206. PMID: 26315981, DOI: 10.1176/appi.ajp.2015.15010055.Peer-Reviewed Original ResearchConceptsExtended-release guanfacineModal doseGuanfacine groupWeek 8Common adverse eventsAutism spectrum disorderWeeks of treatmentAttention deficit hyperactivity disorderDeficit hyperactivity disorderPlacebo groupAdverse eventsBlood pressurePlacebo subjectsClinical trialsSpectrum disorderPlaceboGuanfacineHyperactivityPulse rateHyperactivity disorderGroup differencesMotor planningWeeksBrief cognitive batteryDisorders
2012
Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials
Scahill L, Hallett V, Aman MG, McDougle CJ, Eugene Arnold L, McCracken JT, Tierney E, Deng Y, Dziura J, Vitiello B, the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network). Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials. Journal Of Autism And Developmental Disorders 2012, 43: 739-746. PMID: 23104617, PMCID: PMC3886122, DOI: 10.1007/s10803-012-1689-3.Peer-Reviewed Original ResearchConceptsSocial Withdrawal subscaleSocial disabilityWithdrawal subscaleAcute treatment trialsWeeks of treatmentDouble-blind conditionsAutism spectrum disorderMedication trialsActive treatmentTreatment trialsSpectrum disorderNetwork trialSecondary analysisRisperidoneTrialsPlaceboDisabilityParent trainingSubjectsDisordersTreatmentSubscalesUseful measureResearch UnitWeeks
2008
Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders
Scahill L, Aman MG, McDougle CJ, Arnold LE, McCracken JT, Handen B, Johnson C, Dziura J, Butter E, Sukhodolsky D, Swiezy N, Mulick J, Stigler K, Bearss K, Ritz L, Wagner A, Vitiello B. Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders. Journal Of Autism And Developmental Disorders 2008, 39: 720-729. PMID: 19096921, PMCID: PMC4807607, DOI: 10.1007/s10803-008-0675-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAggressionBehavior TherapyChildChild Development Disorders, PervasiveCombined Modality TherapyDopamine AntagonistsFemaleHumansMaleOutpatientsParent-Child RelationsParentsPatient CompliancePersonality AssessmentPsychiatric Status Rating ScalesRisperidoneSelf-Injurious BehaviorTreatment OutcomeConceptsParent trainingAdaptive functioningPervasive developmental disorderMeasures of noncomplianceBehavioral interventionsSymptom reductionDevelopmental disordersTraining targetClinical treatment targetsTrial design challengesTreatment targetsFunctioningTrainingFunctional improvementLow doseTreatment groupsMedicationsClinical practiceTantrumsAggressionBeneficial effectsIrritabilityChildrenNoncomplianceDisorders