2013
Undertreatment of tobacco use relative to other chronic conditions.
Bernstein SL, Yu S, Post LA, Dziura J, Rigotti NA. Undertreatment of tobacco use relative to other chronic conditions. American Journal Of Public Health 2013, 103: e59-65. PMID: 23763395, PMCID: PMC4007856, DOI: 10.2105/ajph.2012.301112.Peer-Reviewed Original ResearchConceptsTobacco usersTobacco useOffice visitsChronic conditionsNational Ambulatory Medical Care SurveyAmbulatory Medical Care SurveyUS office visitsCommon chronic conditionsCondition-specific treatmentPharmacological treatmentCare SurveyPatient visitsTobacco dependenceBehavioral counselingEffective treatmentHypertensionHyperlipidemiaDiabetesMultivariate analysisAsthmaVisitsTreatmentDepressionOddsComparison condition
2007
A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma
Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA. A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma. New England Journal Of Medicine 2007, 357: 2016-2027. PMID: 18003958, DOI: 10.1056/nejmoa073600.Peer-Reviewed Original ResearchConceptsSerum YKL-40 levelsYKL-40 levelsSeverity of asthmaYKL-40Chitinase-like proteinsParis cohortOral corticosteroid useCohort of patientsRescue inhaler useSubgroup of patientsCirculation of patientsCorticosteroid useSevere asthmaAirway remodelingClinical characteristicsExpiratory volumeAcidic mammalian chitinasePatient populationHigh serumAsthmaImmunohistochemical analysisPatientsAnimal modelsLocus of expressionMorphometric quantitation